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Filtering by: Creator Nandpuri, Karam Singh Remove constraint Creator: Nandpuri, Karam Singh Decade 1990-1999 Remove constraint Decade: 1990-1999

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Enzyme associations in deoxyribonucleotide biosynthesis : anti-idiotypic antibodies as probes for direct protein-protein interactions

Creator:

Young, James Patrick

Abstract:

The ability to faithfully replicate DNA is dependent upon the maintenance and regulation of its precursors, the deoxyribonucleoside triphosphates. Enzymes encoded by the bacteriophage T4 have been widely used as models of biochemical processes. A body of evidence supports the concept that the bacteriophage T4 enzymes involved in deoxyribonucleotide biosynthesis...

Resource Type:

Dissertation
Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:

Hanson, Eric Scott

Resource Type:

Dissertation

Full Text:

aspects of the molecular biology of T4 has recently been published (Karam, 1994). Following adsorption of
Protein-protein interactions in the bacteriophage T4-coded dCTPase-dUTPase

Creator:

Ungermann, Christian

Resource Type:

Masters Thesis
Mutagenic mechanisms associated with perturbations of DNA precursor biosynthesis in phage T4

Creator:

Ji, Jiuping

Abstract:

A crucial factor in determining the accuracy of DNA replication is maintenance of a balanced supply of deoxyribonucleoside triphosphates (dNTPs) at replication forks. Perturbation of dNTP biosynthesis can induce dNTP pool imbalance with deleterious genetic consequences, including increased mutagenesis, recombination, chromosomal abnormalities and cell death. Using the T4 bacteriophage system,...

Resource Type:

Dissertation
Nucleoside diphosphokinase of Escherichia coli and its interactions with bacteriophage T4 proteins of DNA synthesis

Creator:

Ray, Nancy Bisset

Resource Type:

Dissertation
Host kinases involved in DNA precursor biosynthesis during bacteriophage T4 infection

Creator:

Bernard, Mark Aguirre

Abstract:

Although the Escherichia coli host has almost all of the enzymes necessary to synthesize nucleotides needed for bacteriophage T4 DNA replication, phage genes expressed early in infection encode enzymes for de novo DNA precursor biosynthesis and salvage from degraded host DNA. Eight early enzymes and two host enzymes comprise the...

Resource Type:

Dissertation

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Academic Affiliation

Biochemistry and Biophysics5

Advisor

Mathews, Christopher K.6

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 1991 to 1999

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Committee Member

Barofsky, Douglas1
Bayne, Christopher J.1
Hays, J.1
Ho, Shing1
Leong, Jo-Ann1
more Committee Members »

Creator

Bernard, Mark Aguirre1
Hanson, Eric Scott1
Ji, Jiuping1
Ray, Nancy Bisset1
Ungermann, Christian1
more Creators »

Date

Date range begin – Date range end

Current results range from 1990 to 1998

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Decade

1990-1999[remove]6

Degree Field

Biochemistry and Biophysics5
Genetics1

Degree Level

Doctoral5
Master's1

Degree Name

Doctor of Philosophy (Ph.D.)5
Master of Science (M.S.)1

Language

English [eng]6

License

All rights reserved1

Non-Academic Affiliation

Oregon State University. Graduate School6

Peer Reviewed

No6

Resource Type

Dissertation5
Masters Thesis1

Rights Statement

Copyright Not Evaluated5
In Copyright1

Subject

Bacteriophage T46
DNA -- Synthesis4
Escherichia coli -- Genetics3
Proteins -- Reactivity2
Anti-idiotypic antibodies1
more Subjects »

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