Water availability is a critical limiting element in semi-arid ecosystem productivity and presents particular challenges in Sahelian countries such as Senegal. The landscapes are characterized by the presence of two common semi-arid shrubs (Piliostigma reticulatum and Guiera senegalensis), both of which may be important hydraulic regulators in these water-limited ecosystems....
The purpose of this study was to investigate the knowledge base and instructional
practices of two highly qualified experienced secondary mathematics teachers within
the context of their classrooms during a unit in a geometry class. Data collected from
interviews, classroom observations, pre and post-observation questionnaires, and
detailed analyses of several...
The purpose of this study was to develop a profile
of Christian College physical education faculty members
regarding their academic preparation, professional
experience, and selected duties, as well as to identify
important components of graduate preparation at the
doctoral level for future faculty at these
institutions.
A survey instrument was...
Many Hymenoptera, with their painful stings and noxious chemical defenses, exhibit bright aposematic warning color patterns and are the most frequently mimicked group of organisms. Such aposematic color patterns are found in parasitic wasps of the Neotropical Compsobracon group (Braconidae). Many members of this group exhibit color patterns similar to...
The vascular endothelium is a single cell layer that lines the lumen of the entire vasculature. It is the site of synthesis of nitric oxide (NO), a vasodilatory compound synthesized by endothelial nitric oxide synthase (eNOS). NO causes intracellular calcium sequestration of the vascular smooth muscle cells, relaxing and dilating...
Osteoporosis is a skeletal disease affecting 44 million Americans. A primary strategy to prevent osteoporosis is to develop a high peak bone mass in youth. Oral Contraceptives (OCs) alter hormones in women and could affect bone mass development. The interaction between OCs and skeletal mineralization is poorly understood. PURPOSE: Our...
The use of an adjacency matrix to determine distant (not maximal or
minimal) subgroup and supergroup relationships between crystallographic spacegroup
types is described. Full lists of space-group types that are supergroups and
subgroups for every space-group type were compiled. A list of the space-group
types connected to each space-group type...
In a fluidized bed of magnetically susceptible particles, the presence of
a magnetic field induce the formation of particle chains due to interparticle
magnetic forces. The resulting effect is a change in the overall spatial
distribution of the particles, transitioning from a random, isotropic distribution
to an ordered, anisotropic distribution....
With respect to a multienzyme complex of deoxyribonucleoside triphosphate (dNTP) synthesis somehow juxtaposed with DNA replication sites, our laboratory has demonstrated the existence of a multienzyme complex in T4-infected E. coli, named the T4 dNTP synthetase complex, but the idea of direct linkage of dNTP synthesis to DNA replication and...
Four-stranded DNA junctions (also known as Holliday junctions) are structural intermediates involved in a growing number of biological processes including DNA repair, genetic recombination, and viral integration. Although previous studies have focused on understanding the conformational variability and sequence-dependent formation of Holliday junctions in solution there have been relatively few...
The study evaluates the effectiveness of a pregnancy intervention model (PIM) developed to improve first trimester prenatal care utilization in a population of 2,694 low-income Medicaid women. Engagement in prenatal care is critical before prenatal care can occur. Early initiation of prenatal care is important for low income pregnant women...
Vaccinia virus (VV) is a large double-stranded DNA virus that is a prototypic member of the orthopoxvirus family. Previous works has showed that three of the major structural proteins found within the mature VV virion core 4a, 4b, and 25K are produced from higher molecular weight precursors at late times...
Cultural competence is a topic that concerns social scientists and medical anthropologists who pay attention to demographic changes and health disparities. This study demonstrates practical approaches to developing cultural competence in medical education by using factors from the social environment to develop protocols for action. With current concerns in domestic...
The purpose of this research was to hear the stories of Northern Cheyenne women's educational experiences using the method of testimonio, a method culturally aligned and academically appropriate for use among indigenous people. The researcher, also a Northern Cheyenne tribal member used testimonio based on its roots in resistance literature...
Foliar respiration forms a large component of the carbon balance of any coniferous forest. We examine seasonal, interannual, spatial and interspecific variation of foliar maintenance respiration in a forest in Washington, USA, with measurements made quarterly for >4 years on 400-year old trees of Pseudotsuga menziesii, Tsuga heterophylla and Thuja...
After 22 years of eruption at Kilauea Volcano, Hawai'i, an environmental, epidemiological, and ethnographic study was conducted to assess for adverse health effects from chronic exposure to volcanogernc air pollution. Environmental data from 2003 indicated that Kau District, from 37 to 74 km downwind from the eruption, was being exposed...
Careful analysis and thoughtful synthesis will be necessary for expanding the envelope of
ecological understanding. This work is my attempt at communicating both of these, in relation
to three questions about our understanding of the structure and dynamics of biological diversity.
These questions focus on a) advancing our understanding of...
This study was designed to investigate a phenomenon, retention of Hispanic adult second language learners in Washington State's community colleges, from a qualitative paradigm and phenomenological approach. The focus of this study was to capture eight foreign-born Hispanic ESL non-continuators' voices and experiences, in their native language of Spanish, who...
The purpose of this research was to determine whether hybridization between Amelanchier denticulata. (H.B.K.) Koch and Amelanchier nervosa (Decaisne) StandL occurs in Oaxaca, Mexico, and to evaluate components of yield and germination characteristics and seed dormancy of Amelanchier denticulata. Amelanchier nervosa and Amelanchier denticulata samples and morphological characters were used...
Cordyceps is a genus of perithecial ascomycetes. It includes over 400 species
that are pathogens of arthropods and parasites of the truffle genus Elaphomyces. Based
on the morphology of cylindrical asci, thickened ascus apices and filiform ascospores,
it is classified in the Clavicipitaceae (Hypocreales), which also includes endophytes
and epiphytes...
In this dissertation, I present electronic spectroscopy of a few biologically relevant species and their complexes with solvent molecules in the gas phase using a variety of techniques, including resonantly enhanced multiphoton ionization (REMPI), laser induced fluorescence (LIF), and zero kinetic energy (ZEKE) photoelectron spectroscopy. My work on several methylated...
The appropriate separation of concerns is a fundamental engineering principle. A concern, for software developers, is that which must be represented by code in a program; by extension, separation of concerns is the ability to represent a single concern in a single appropriate programming language construct. Advanced separation of concerns...
The objectives of the experiment were to: 1) determine the relationship
between overstory canopy cover and ungulate herbivory on understory production
composition and diversity and 2) determine the effects of timber harvest, ungulate
herbivory and season of use on botanical composition and nutritional quality of
beef cattle diets. Three randomly...
In recent years, the methyl erythritol phosphate (MEP) pathway to isoprenoids has been the subject of intensive research. The interest is because isoprenoids have important roles in many cellular processes essential for the survival of several pathogenic organisms, making the inhibition of this pathway an attractive target for the drug...
Task prioritization performance was evaluated for pilots who participated in a concurrent task management (CTM) training course and pilots who did not. CTM is the process by which pilots selectively attend to high priority tasks and shed non-priority tasks. Twenty seven pilots enrolled in a university flight technology program were...
Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled
signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well
characterized, but little is known about other protein interactions that may also
regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library
with...
Halogenated monoterpene production by the red macroalga Octhodes secundiramea was studied-under different levels of nutrient, bromide, vanadium and light delivery. The key products formed were identified as myrcene, betaelemene, the Z and E isomers of l0-bromomyrcene, 3-chloro-10E-bromomyrcene, Apakaocthodene A, and isomers of chloromyrcene and dibromomyrcene. The proposed pathway begins with...
New transparent p- and n-type semiconductors and luminescent materials have been prepared and characterized. Synthesis, structures, optical and electrical properties of new chalcogenide fluoride p-type transparent semiconductors MCuQF (M=Ba, Sr; Q=S, Se, Te) are described. Band-gap tuning and improvement in conductivity through p-type doping are demonstrated in the family. The...
Indole-3-carbinol (I3C) and 3,3'-diindolylmethane (DIM), a primary I3C
derivative in vivo, are known chemopreventive agents available as dietary supplements.
I3C was found to suppress or enhance tumors in several animal models.
Chemoprotection is attributed to the ability of indoles to alter carcinogen metabolism
effectively blocking initiation. However, mechanisms for enhancement...
This thesis involves analyses of 3₂-helices, a-helices and of the change in residual
entropy of a protein upon chemical modification. Part of the long-term goal of
understanding the formation, function and stability of proteins requires that all
conformations be accurately assigned and structurally understood. By a statistical
analysis of 258...
A theoretical argument is presented to suggest that engineering curriculum be
designed to develop social capital. Additionally, the value of social capital in the
retention of students in the College of Engineering, and the development, role, and value
of social capital in an electrical engineering laboratory is evaluated. Data collected...
The unifying purpose of this dissertation was to describe, model, and map
relationships between epiphvtic macrolichen communities and air quality in Ibrests of
northern and central California. First, multivariate analyses were used to subdivide the
large study area into three model areas with similar climate, topography, and lichen
communities: the...
My dissertation focuses on the factors that influence variation in female reproductive success in plethodontid salamanders and in toads. Variation in reproductive success fuels evolutionary change. Although, females often have been overlooked in studies of reproductive success due to perceived lower levels of variation when compared to variation in male...
In this thesis, novel solutions are proposed for key management issues in mobile ad hoc networks. Presented Hierarchical Binary Tree (HBT) based model is distributed, self-organizing, scalable and does not employ online key distribution authority or group manager. Two different group authentication and group key establishment protocols are proposed for...
Over the last decade, the miniaturization of analytical systems has become an increasingly important and interesting research area. Miniaturized systems offer many advantages, including reduced reagent and sample consumption, shorter analysis times, portability and disposability. This dissertation describes novel approaches in this direction, focusing on two areas: the miniaturization of...
Crown gall disease is an agricultural problem caused by the soil-borne bacterium, Agrobacterium tumefaciens. A. tumefaciens oncogenes cause transformed plant cells to overproduce the hormones, auxin and cytokinin. High hormone levels cause unorganized plant cell growth resulting in a gall. Control of crown gall disease is difficult because after plant...
Questions relating to economic performance, biological conservation and variation in resource abundance and harvest of ocean shrimp have led to increasing pressure for management action. Developing effective management policies for this highly variable resource requires a comprehensive understanding of the fishery and marine processes. Important factors in understanding the fishery...
PURPOSE: To compare glenohumeral joint position sense (JPS), concentric internal (IR) and external rotation (ER) strength, functional ability, and level of satisfaction in patients who underwent three types of glenohumeral capsulorrhaphy with age-matched controls. RESEARCH DESIGN: Four 4x2 and two 4x3 ANOVAs were used to identify differences in JPS and...
This study consisted of two research projects in the Wyoming big sagebrush (Artemisia tridentata ssp. wyomingensis (Beetle & A. Young) S.L. Welsh) alliance, the most extensive of the big sagebrush complex in the Intermountain West. In the first project, we intensively sampled 107 relatively undisturbed, late seral Wyoming big sagebrush...
A convergent synthesis of epothilone B that generates all seven of its
asymmetric centers in a completely stereoselective fashion has been
completed. Key reactions include an anti-Felkin aldol condensation to
set the C6 and C7 stereochemistry, a directed α-hydroxylation to install
the C15 (S)-hydroxyl substituent, and a Wittig condensation to...
Population genetic structure is widespread in many organisms and can be found at small spatial scales. Fine-scale differentiation is the result of ecological and evolutionary processes working together to produce an overall pattern, but the relative importance of these factors in population differentiation is poorly understood. The goals of my...
Jets in crossflow are used in a wide range of engineering applications and have been studied for more than 60 years. The transversal penetration and structure of a jet placed in a crossflow is known to be strongly three-dimensional. It is believed that, by using a pulsed jet inclined in...
It is well known that the mitochondrial genome has a much higher spontaneous mutation rate than the nuclear genome. mtDNA mutations have been identified in association with many diseases and aging. mtDNA replication continues throughout the cell cycle, even in post-mitotic cells. Therefore, a constant supply of nucleotides is required...
The rearrangement of a homoallyl cation to a cyclopropylcarbinyl cation is thought to play a role in the biogenesis of a variety of cyclopropane-containing natural products,¹ a hypothesis which has previously led to the design of successful biomimetic syntheses of several natural products.² The strategy underlying this approach to cyclopropane...
Courtship and copulation behaviors in Drosophila melanogaster males are regulated by sex-specific products from the gene fruitless (fru). Male-specific FRU proteins (FRU[superscript M]) are putative transcription factors of the BTB-ZnF family that likely act by controlling development and maintenance of the neural circuitry used during male sexual behavior. However, which...
This research sought to identify the reasons physicians attributed for practicing in Oregon, the reasons for relocating out of Oregon, and the reasons for failures in recruiting physicians to Oregon. A random sample survey of 494 Oregon physicians identified the presence of economic and non-economic factors related to the recruitment...
Enzymes play an important role in the environment, they breakdown natural-occurring and anthropogenic molecules so that they can be transported into cells and utilized. Enzyme assays are routinely used in soil science and oceanography to measure the activities of specific processes and to serve as general indicators of microbial activity....
This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Tan spot of wheat is an economically significant disease caused by the fungal pathogen, Pyrenophora tritici-repentis. Certain races of the fungus secrete Ptr ToxA (ToxA), a 13.2 kDa proteinaceous host-selective toxin that is responsible and sufficient to cause disease in susceptible wheat varieties. Disease symptoms develop only when the ToxA...