Digital-to-analog converters (DACs) with wide dynamic range and high
linearity are required for high-end audio applications. A multi-bit delta sigma
audio DAC, using a novel gain-correction technique, is described in this thesis. For
widely varying on-chip RC time constant, the DAC gain can be accurately
controlled by the correction circuitry....
Evolution of the mobile communication standards and proliferation of hand-held devices mandate stringent Analog-to-Digital Converter (ADC) specifications. Among various ADCs, a ∆Σ ADC is best known as a power-efficient ADC when more than 12b is required. However, a conventional discrete-time (DT) ∆Σ Modulator (∆ΣM) is inadequate for low-power wideband applications...
The National Council of Teachers of Mathematics published their vision of active, problem-centered instruction with a goal of conceptual understanding in 1989. Fifteen years after these reforms were proposed the changes are reflected in school policy and elementary mathematics curriculum, but only limited change has actually occurred in classroom instruction....
Physical distribution is one of the key functions in logistics systems, involving the flow of products from manufacturing plants or distribution centers through the network of transportation to consumers. The function is very costly, especially for the distribution industries. During the past decades, the significance of physical distribution has increased...
Using network architecture to describe a biological system is an effective organizational method. The utility of this approach, which generally applies to qualitative models, is enhanced by the addition of quantitative models characterizing the interactions between network nodes. A chromatophore-based signal transduction network is developed, and the highly interconnected major...
The main result of this written dissertation is a mathematical solution to the problem of multiplex recording for high performance tandem time-of-flight mass spectrometry. The prescription is to use a time-lag accelerator in the second stage to match the ion optical properties of the decay fragments to the requirements of...
The use of an adjacency matrix to determine distant (not maximal or
minimal) subgroup and supergroup relationships between crystallographic spacegroup
types is described. Full lists of space-group types that are supergroups and
subgroups for every space-group type were compiled. A list of the space-group
types connected to each space-group type...
In this work, a multicomponent lattice Boltzmann model is developed for the simulation of multiphase mixing, reactions, and separations processes. This model is unique in that diffusive mass transfer of a component in the model is driven by gradients of chemical potential. This fundamentally correct description of diffusion accurately captures...
Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...
This thesis describes evaluation of a novel self-sealing chewable sustained release tablet that can maintain controlled release of drug regardless of compaction, crushing, or chewing. The new formulation contains polyethylene oxide which produces a sealant effect for cracks produced in the polymer coating during compaction. Dissolution studies were conducted and...