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Filtering by: Committee Member Ho, P. Shing Remove constraint Committee Member: Ho, P. Shing Decade 2000-2009 Remove constraint Decade: 2000-2009 Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

    Creator:
    Hooven, Louisa Ada
    Abstract:
    Exposure to polycyclic aromatic hydrocarbons such as benzo[a]pyrene (B[a]P) has been determined to be a risk factor for various forms of human cancer. PAH DNA adducts have been shown to cause mutations, but carcinogenesis is also accompanied by alterations in gene expression. Inhibiting individual cytochrome P450s could clarify the interaction...
    Resource Type:
    Dissertation
    Full Text:
    unwavering support. My appreciation is also extended to Dr. P. Shing Ho, Dr. Christopher K. Mathews, and Dr

  • Electron molecule interactions of amino acids and peptides

    Creator:
    Figard, Benjamin J.
    Abstract:
    Electron-biomolecule interactions are a biologically relevant field of study because there are several ion fragmentation techniques that have come to the forefront in mass spectrometric analysis that involve the interaction of charged peptides and free electrons. By studying the electron energies that cause fragmentation in neutral amino acids, amino acid...
    Resource Type:
    Dissertation
    Full Text:
    peptide substance P. For peptides with carboxylic acids on the C-terminus, z-1 ions were observed