Index Catalog // ScholarsArchive@OSU

Search for a repressor regulator of invasion in Mycobacterium avium

Creator:: Tripathi, Sanjai T.
Abstract:: Mycobacterium avium is an intracellular pathogen that is associated with disseminated infection, especially in patients with acquired immunodeficiency syndrome (AIDS). It appears that patients with AIDS acquire M. avium mostly through the intestinal tract, and that bacteria enter the intestinal wall at the terminal ileum. Previous studies have found that...
Resource Type:: Masters Thesis

Developing a system of mutagenesis in Francisella tularensis LVS

Creator:: Flax, Lindsay A.
Abstract:: Francisella tularensis is a gram-negative facultative intracellular coccobacillus that primarily infects macrophages. The causative agent of tularemia, this bacterium is considered among the most infectious organisms known, requiring fewer than ten organisms to cause disease. Although ubiquitous in nature, transmission to humans is rare but can occur via insect bites,...
Resource Type:: Masters Thesis

Analysis of Bacteroidales 16S rRNA gene sequences from a geographically isolated human population

Creator:: Petersen, Carolyn A.
Abstract:: Standard methods of measuring fecal pollution in water do not distinguish between human and non-human sources. Molecular technology enabled the development of host-specific markers that distinguish fecal sources. Human specific PCR primers, HF183F and HF134F, were designed based on phylogenetic analyses of partial 16S rRNA gene sequences from the Bacteroidales...
Resource Type:: Masters Thesis

Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

Creator:: Raju, Deepa
Abstract:: Clostridium perfringens type A isolates producing enterotoxin (CPE) are an important cause of both food poisoning (FP) and non food borne gastrointestinal diseases (NFBGID) in both humans and animals. C. perfringens type A food poisoning is caused by isolates carrying the CPE encoding gene (cpe) on the chromosome while the...
Resource Type:: Dissertation

Identification of an aerotaxis transducer in Vibrio cholerae

Creator:: Boin, Markus A.
Abstract:: The ability to move towards favorable environmental conditions, called chemotaxis, is common among motile bacteria. In particular aerotaxis has been extensively studied in Escherichia coli. Three putative aer gene homologs were identified in the V. cholerae genome designated VCAer-1 (VC0512) VCAer-2 (VCA0658), and VCAer-3 (VCA0988). Deletion analyses indicated that only...
Resource Type:: Masters Thesis

Characterization of the genomic islands from tetracycline-resistant Chlamydia suis

Creator:: Dugan, Jae
Abstract:: Tetracycline (Tet)-resistant strains of Chlamydia suis were isolated from swine farms in the Midwest. The isolation of the resistant strains was significant because Tet is an antibiotic used to treat infections by veterinarians and doctors. One of the tetracycline (Tet)-resistant strains, R19, was able to survive in Tet up to...
Resource Type:: Dissertation

Mechanisms for the interaction of environmental mycobacteria with host cells

Creator:: Harriff, Melanie J.
Abstract:: Environmental mycobacteria are important opportunistic pathogens for many hosts, including humans, cattle, and fish. Two well-studied species are Mycobacterium avium subsp. avium, a significant cause of disseminated bacterial disease in patients with AIDS, and Mycobacterium avium subsp. paratuberculosis, the cause of Johne’s disease in cattle. Many other species that are...
Resource Type:: Dissertation

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Creator:: Starkenburg, Shawn R.
Abstract:: The chemolithoautotrophic nitrite oxidizing bacteria (NOB) participate in the biogeochemical cycling of nitrogen by catalyzing and conserving energy from the oxidation of nitrite (NO₂-) to nitrate (NO₃-) via a nitrite oxidoreductase (NXR). The main objective of this work was to comparatively annotate and analyze the genome sequences of Nitrobacter winogradskyi...
Resource Type:: Dissertation

Physiological, proteomic, and whole-genome transcriptional responses of Nitrosomonas europaea to heavy metals (Zn²⁺,Cd²⁺, Cu²⁺, and Hg²⁺) and cyanide : identification of heavy metals and cyanide stress response genes

Creator:: Park, Sunhwa
Abstract:: Nitrosomonas europaea (ATCC19718) participates in the biological removal of nitrogen from wastewater by oxidizing ammonia to nitrite, the first step in nitrification. This bacterium is sensitive to heavy metals (Zn²⁺, Cd²⁺, Cu²⁺, and Hg²⁺) and cyanide, compounds commonly encountered in wastewater treatment plants. Therefore, we characterized physiological and transcriptional responses...
Resource Type:: Dissertation

Prokaryotes associated with marine crust

Creator:: Mason, Olivia Underwood
Abstract:: Oceanic crust covers nearly 70% of the Earth's surface, of which, the upper, sediment layer is estimated to harbor substantial microbial biomass. Marine crust; however, extends several kilometers beyond this surficial layer, and includes the basalt and gabbro layers. In particular, the basalt layer has high permeabilities which allows for...
Resource Type:: Dissertation

ScholarsArchive@OSU

Search for a repressor regulator of invasion in Mycobacterium avium

Developing a system of mutagenesis in Francisella tularensis LVS

Analysis of Bacteroidales 16S rRNA gene sequences from a geographically isolated human population

Molecular basis for Clostridium perfringens spore resistance to heat and other environmental stress factors

Identification of an aerotaxis transducer in Vibrio cholerae

Characterization of the genomic islands from tetracycline-resistant Chlamydia suis

Mechanisms for the interaction of environmental mycobacteria with host cells

An investigation of carbon and nitrogen metabolism through a genomic analysis of the genus Nitrobacter

Physiological, proteomic, and whole-genome transcriptional responses of Nitrosomonas europaea to heavy metals (Zn²⁺,Cd²⁺, Cu²⁺, and Hg²⁺) and cyanide : identification of heavy metals and cyanide stress response genes

Prokaryotes associated with marine crust

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