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Filtering by: Creator Li, Xin Remove constraint Creator: Li, Xin Decade 2000-2009 Remove constraint Decade: 2000-2009 Non-Academic Affiliation Oregon State University. Honors College Remove constraint Non-Academic Affiliation: Oregon State University. Honors College

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  • Pathogenic Mechanisms of Cancer Causing hMLH1 Mutations

    Creator:
    O'Donnell, Edmond Francis
    Abstract:
    DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
    Resource Type:
    Honors College Thesis
    Full Text:
    patience and guidance throughout my research experience. Thanks are also owed to Xin Hou, Azizah Mohd