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Filtering by: Advisor Proteau, Philip J. Remove constraint Advisor: Proteau, Philip J. Decade 2000-2009 Remove constraint Decade: 2000-2009

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  • Studies of non-mevalonate isoprenoid biosynthesis : the 1-deoxy-D-xylulose-5-phosphate isomeroreductase (DXR) mediated reaction

    Creator:
    Woo, Youn-Hi
    Abstract:
    This dissertation details the investigation of an alternate pathway to isoprenoids that occurs in plants and microorganisms, the non-mevalonate pathway. This exploration of the pathway focuses on the second step, the conversion of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methylerythritol-4-phosphate (MEP) by the enzyme DXP isomeroreductase (DXR). These studies led to an appreciation...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Phil Proteau for his support, continual inspiration, and endless patience as a mentor, in

  • Studies on isoprenoid biosynthesis in Euglena gracilis

    Creator:
    Kim, Dojung
    Abstract:
    This dissertation describes studies of isoprenoid biosynthesis in the phytoflagellate Euglena gracilis. Elucidation of a novel isoprerioid pathway, the 2-Cmethyl-D-erythritol-4-phosphate (MEP) pathway, in addition to the generally known mevalonate (MVA) pathway, led to extensive exploration of the distribution of both pathways in a variety of organisms. To date, photosynthetic eukaryotes...
    Resource Type:
    Dissertation
    Full Text:
    thank my major Professor, Philip J. Proteau, for his support, guidance, and patience throughout my

  • Syntheses and evaluation of putative enzyme inhibitor of isoprenoid biosynthesis

    Creator:
    Phaosiri, Chanokporn
    Abstract:
    The discovery of the methylerythritol phosphate pathway (the MEP pathway) as an alternate pathway for isoprenoid biosynthesis in some organisms including most bacteria, malarial parasites and plants, but not in animals, has stimulated extensive studies in this area. Research has revealed the potential of finding novel antibacterials, antimalarial drugs, and...
    Resource Type:
    Dissertation
    Full Text:
    foremost, II would like to thank my major professor, Dr. Philip Proteau for his advice, guidance, and

  • Studies on 1-deoxy-D-xylulose 5-phosphate reductoisomerase from Synechocystis sp. PCC6803 : characterization of mutants and inhibitors

    Creator:
    Fernandes, Roberta P. M.
    Abstract:
    In recent years, the methyl erythritol phosphate (MEP) pathway to isoprenoids has been the subject of intensive research. The interest is because isoprenoids have important roles in many cellular processes essential for the survival of several pathogenic organisms, making the inhibition of this pathway an attractive target for the drug...
    Resource Type:
    Dissertation
    Full Text:
    Inhibitors. Abstract approved: hilip/(Proteau In recent years, the methyl erythritol phosphate (MEP

  • Biosynthetic studies of fungal diterpene antibiotics

    Creator:
    Yao, Qingmei
    Abstract:
    The isoprenoid pathway is one of the major biosynthetic pathways of secondary metabolites. Isoprenoids with a C₂₀ skeleton are known as diterpenoids and are derived from the common precursor, geranylgeranyl diphosphate (GGPP). This dissertation describes approaches to discover the diterpene synthase enzymes which provide the backbone structures for pleuromutilin and...
    Resource Type:
    Masters Thesis
    Full Text:
    Abstract approved: __________________________________________ Philip J. Proteau The isoprenoid

  • Time Periodic Sand Ripples at the Oregon Coast

    Creator:
    Korn, Abraham
    Abstract:
    We consider development of sand ripples in shallow water flows which do not reach an equilibrium height but have a time-varying ripple height that slowly reaches a maximum value and then is quickly destroyed by the fluid. A simple scenario to explain the time periodic behavior of the sand ripples...
    Resource Type:
    Honors College Thesis
    Full Text:
    Oregon Coast Abstract approved: Dr. Philip J. Siemens We consider development of sand ripples in

  • Contribution from two on-shell pion exchange in nucleon-nucleon scattering

    Creator:
    Kheaomaingam, Nupan
    Abstract:
    We used recent phenomenological form factors to calculate the effect of on-shell two-pion exchange in nucleon-nucleon scattering below the two-pion production threshold. As expected, the contributions of partial wave amplitudes are all negligible. We also noticed that the relativistic spin-operator decomposition of the scattering amplitude is not unique at certain...
    Resource Type:
    Dissertation
    Full Text:
    in Nucleon-Nucleon Scattering Abstract approved: Philip J. Siemens We used recent

  • Unusual quantum effects in scattering wave functions of two-dimensional cage potentials

    Creator:
    Rowe, Kirk, 1966-
    Abstract:
    We exhibit long-lived resonances in scattering from two-dimensional soft cage potentials comprised of three and four Gaussian peaks. Specific low-energy resonances with very narrow width are shown to correspond to classical multiple-reflection events. These states have much larger probability densities inside the cage than outside and mimic bound states in...
    Resource Type:
    Dissertation
    Full Text:
    Scattering Wave functions of Two-Dimensional Cage Potentials. Abstract approved: Philip J. Siemens We

  • Carbon fiber as a resistive heat generator to accelerate adhesive cure in reinforced wood laminates

    Creator:
    Liem, Jeffry
    Abstract:
    As a result of its atomic structure, carbon fiber produced from mesophase pitch has a high electrical conductivity and high tensile strength. Others have used carbon fiber as a resistive heating unit to accelerate matrix solidification in carbon fiber-polymer matrix composites. In this study, a unidirectional carbon fiber reinforced polymer...
    Resource Type:
    Masters Thesis