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Filtering by: Creator Bair, Russell Decade 2000-2009

The Hanford Laboratories and the growth of environmental research in the Pacific Northwest, 1943 to 1965

Creator:

Ellis, D. Erik

Abstract:

The scientific endeavors that took place at Hanford Engineer Works, beginning in World War II and continuing thereafter, are often overlooked in the literature on the Manhattan Project, the Atomic Energy Commission, and in regional histories. To historians of science, Hanford is described as an industrial facility that illustrates the...

Resource Type:

Masters Thesis
A novel mechanism of chemoprevention by sulforaphane : inhibition of histone deacetylase

Creator:

Myzak, Melinda C.

Abstract:

Targeting the epigenome, including the use of histone deacetylase (HDAC) inhibitors, is a novel strategy for cancer chemoprevention. Sulforaphane (SFN), a compound found at high levels in broccoli and broccoli sprouts, is a potent inducer of Phase 2 detoxification enzymes and inhibits tumorigenesis in animal models. SFN also has a...

Resource Type:

Dissertation