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  • Hemoglobin adducts of the organophosphate insecticide azinphos-methyl

    Creator:
    Bailey, Bonnie J.
    Abstract:
    Reported here is an investigation to determine if azinphos-methyl (AZM), an organophosphate insecticide, adducts to hemoglobin, and if so, whether the hemoglobin adduct could be used as a quantitative marker of occupational AZM exposure. We hypothesized that AZM, or a metabolite of AZM, binds to hemoglobin in erythrocytes forming an...
    Resource Type:
    Dissertation
    Full Text:
    physiological role for that enzyme has been defined, use of the term cholinesterase assumes AChE unless

  • Indole-3-carbinol and 3,3'-diindolylmethane : relative potency as modulators of drug metabolism and carcinogenesis

    Creator:
    Katchamart, Sirinmas
    Abstract:
    Indole-3-carbinol (I3C), the most abundant metabolite of glucobrassicins, is found in cruciferous vegetables such as broccoli, Brussels sprouts, cabbage and cauliflower. I3C has been shown to have anticarcinogenic activity against many chemical carcinogens in multiple target organs in animal models. However, the anticarcinogenic activity of I3C is considered indirect since...
    Resource Type:
    Dissertation
    Full Text:
    supplementation are its estrogenic effect as seen in trout and its ability to induce cytochrome P45 Os involved

  • Composition of flavonoid phenolic polymers isolated from red wine during maceration and significance of flavan-3-ols in foods pertaining to biological activity

    Creator:
    Aron, Patricia M.
    Abstract:
    Representing the most common flavonoid consumed in the American diet, the flavanols and their polymeric condensation products, the proanthocyanidins, are regarded as functional ingredients in various beverages, whole and processed foods, herbal remedies and supplements. Their presence in food affects food quality parameters including astringency, bitterness, sourness, sweetness, salivary viscosity,...
    Resource Type:
    Masters Thesis
    Full Text:
    Effect on food quality............................................................................6

  • Purification and characterization of recombinant calpain-5

    Creator:
    Wang, Mei-Chuan
    Abstract:
    Recombinant human calpain-5 was expressed in insect cells using a baculovirus system. The expressed calpain-5 was purified by both traditional chromatography and by affinity-column chromatography. Both methods yielded active protease. Calpain-5 displayed very limited hydrophobicity. This indicated that calpain-5 is not a membrane binding protein. Calpain-5 had pI of 8.3....
    Resource Type:
    Dissertation
    Full Text:
    cysteine proteases. Although the exact physiological roles of calpains remain to be elucidated, calpains

  • Estimation of the energy cost of walking 10,000 steps

    Creator:
    Birdsley, Kari L.
    Abstract:
    There is a strong campaign underway to promote increased physical activity among the U.S. population. The U.S. Surgeon General and the U.S. Dietary Guidelines have presented physical activity recommendations in terms of the amount of time accumulated in physical activity and/or in terms of energy expenditure over the course of...
    Resource Type:
    Masters Thesis
    Full Text:
    activity has a positive effect on one's physical well being. The American College of Sports Medicine

  • Exercise, nutrition, and homocysteine

    Creator:
    Joubert, Lanae Marie
    Abstract:
    Exercise increases B-vitamin (B6, B12, folate) dependent metabolic reactions, especially those related to energy production and the rebuilding and repairing of muscle tissue. These same B-vitamins are also important in maintaining low blood levels of homocysteine (Hcy), a cardiovascular disease (CVD) risk factor. Hcy levels rise when the metabolism of...
    Resource Type:
    Dissertation
    Full Text:
    exercise intensity is vigorous. Research examining the effect of exercise on Hcy is limited with no

  • Impact of weak and strong acids on the destruction of lactic acid bacteria during high pressure processing

    Creator:
    Sarangapani, Rama Krishna
    Abstract:
    High hydrostatic pressure (HHP) affects the pH of weak acids due to an increased degree of acid dissociation while under pressure. The temporary pH reduction by high pressure in such a case may influence the barotolerance of microorganisms. The objective of this study was to determine the impact of weak...
    Resource Type:
    Masters Thesis
    Full Text:
    bacteria across a range of pH under high hydrostatic pressure conditions. The effect of two acid groups

  • Steroids regulate α2,6-sialic acid-containing glycoconjugates in murine uterine epithelium at the time of implantation

    Creator:
    Gaza-Bulseco, Georgeen S.
    Abstract:
    Sialic acids are involved in many cellular interactions. They can serve as an adhesion ligand or act as an inhibitor to cellular adhesion by charge repulsion or by masking potential ligands. Although sialic acids are implicated in the process of blastocyst implantation, their expression and regulation in uterine epithelium of...
    Resource Type:
    Masters Thesis
    Full Text:
    , staining was most intense in mice injected with estradiol alone, and no staining was evident in mice

  • The effect of two levels of glucose ingestion on plasma pyridoxal 5'-phosphate concentration

    Creator:
    Huang, Ying-Hui
    Abstract:
    This study was designed to evaluate the effect of glucose on plasma pyridoxal 5'- phosphate (PLP) concentration. The objective was to determine whether there was a negative relationship between glucose ingestion and plasma PLP concentration and to evaluate the possible mechanism of decreased PLP after acute glucose ingestion. Seven healthy...
    Resource Type:
    Masters Thesis
    Full Text:
    Master of Science in Nutrition and Food Management presented on January 11, 2000. Title: The Effect of

  • Fibrinogen adsorption at heparinized silica interfaces : history dependence and protein concentration effects

    Creator:
    Joshi, Omkar
    Abstract:
    Adipic dihydrazide-modified heparin was prepared and subsequently immobilized on surface-activated silica wafers. X-ray photoelectron spectroscopy (XPS) was used to quantify the elemental composition of the silica surface at each stage of activation and results showed that successful immobilization had taken place. Contact angle measurements were made to verify the high...
    Resource Type:
    Masters Thesis
    Full Text:
    possible alternative is heparin immobilization on the biomaterial, so that the anticoagulant effect will