In order to quantify changes in export production and carbonate dissolution over the past 1 Myr in the
central equatorial Pacific Ocean we analyzed Ba, P, Al, Ti, and Ca in 1106 samples from five piston cores gathered from
5°S to 4°N at 140°W. We focused on Ba/Ti, Al/Ti, and...
Rat selenoprotein W (SeW) promoter activity was investigated using different concentrations of cadmium, copper, and zinc. Two fragments (404bp and 1265bp) of the SeW promoter, containing a single metal response element (MRE), were ligated into the multiple cloning site of a pGL3-Basic reporter plasmid. The constructs were transfected into cultured...
Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled
signaling pathways. Prior research suggested that some isoforms of PLC-β may exist
and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation
assays of differentially-tagged PLC-β constructs and sizeexclusion
chromatography of native PLC-β support homodimerization...
Ascorbic acid, or vitamin C, is well known as a co-factor for proline-hydroxylase and as an anti-oxidant. However, it is also capable of forming covalent bonds, particularly in the role of a nucleophile, henceforth termed 'ascorbylation'.
The ascorbylation of electrophiles can occur under physiological conditions. Furthermore, there are a number...
The purpose of this study is to examine the rhetorical efforts of President George W. Bush in defending his administration's warrantless wiretapping program. Specifically, the study attempts to determine the president's underlying motives when he defended the National Security Agency in a December 2005 radio address by applying Kenneth Burke's...
Selenoprotein W (SeW) is a protein whose function is unknown, but potentially plays a vital role in calcium metabolism, as an indirect link has been established with white muscle disease (WMD). White muscle disease occurs in selenium deficient animals, and is characterized by the precipitation of calcium in muscle, leading...
Phospholipase C-Jβ (PLCβ) is an important effector enzyme in G-protein-coupled
signaling pathways. Activation of PLCβ by Gα and Gβy subunits has been fairly well
characterized, but little is known about other protein interactions that may also
regulate PLCβ function. A yeast two-hybrid screen of a mouse brain cDNA library
with...
High electron mobility thin films of In₂₋ₓWₓO₃₊y(0≤x≤0.075) were prepared on amorphous SiO₂ and single-crystal yttria-stablized zirconia (001) substrates by pulsed laser deposition. Mobilities ranged between 66 and 112 cm² /Vs depending on the substrate type and deposition conditions, and the highest mobility was observed at a W-dopant concentration of x~0.03....