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Filtering by: Creator Plésiat, E. Decade 2000-2009

Clinical pharmacokinetic simulation/modeling as a tool for therapeutic drug monitoring and dose adjustment in special patient populations

Creator:

Mohamed, Osama H.

Abstract:

This dissertation describes how to apply pharmacokinetic simulations and modeling in a clinical setting to monitor and adjust drug dosing in special patient populations. Pharmacokinetic simulations were used to investigate efficacy and risk of drug toxicity of a new dosing regimen for aminoglycoside antibiotics when administered to renal failure patients....

Resource Type:

Dissertation
Detection of the Burkholderia cepacia complex in soil environments

Creator:

Miller, Suzanne C. McKenzie

Abstract:

Burkholderia cepacia complex (Bcc) bacteria reside in soil, plant rhizospheres, and water, but the prevalence of Bcc in outdoor environments is not clear. In this study, we sampled a variety of soil and rhizosphere environments with which people may have contact: playgrounds, athletic fields, parks, hiking trails, residential yards and...

Resource Type:

Masters Thesis

Full Text:

found to induce the inflammatory marker tumor necrosis factor c (TNF-a) to levels achieved by E. coli