7,7'-Dihydroxy-8,8'-biquinolyl (azaBINOL) was prepared from 7-hydroxyquinoline via N,N-dimethyl O-quinol-7-yl carbamate by directed ortho-metallation followed by FeCl₃-mediated oxidative coupling of the 8-lithioquinoline intermediate. Saponification of the resulting dicarbamate provided crystalline (±)-azaBINOL in 56% overall yield. 6,6'-Bis(dimethylaminocarbonyl)-7,7'-dihydroxy-8,8´-biquinolyl was prepared from the same dicarbamate by a double anionic-Fries rearrangement in 43% yield. 7,7'-Bis(diethylamino-carbonyloxy)-6,6'-diiodo-8,8´-biquinolyl...
Over-winter growth of juvenile salmonids may be linked to ocean survival and thus species persistence. Diet, growth, and prey available to juvenile coho, Oncorhynchus kisutch, were examined from December 2004 to April 2005 in four tributaries of the West Fork Smith River (WFSR), Oregon. Juvenile coho growth rate and condition...
The ultimate goal of large-scale design organizations are mainly to reduce costs and improve reliability and performance of systems while assessing how much risk (cost, schedule, scope) they can take and still remain competitive. To achieve this goal they need to develop tools to reach the most preferred design product...
Excavations performed at the historic Smith House (ORYA3) located in
Dayton, Yamhill County, Oregon, recovered a large collection of artifacts. Categories
of artifacts previously analyzed include flat glass, nails, glass containers, ceramic
hollowware and flatware, brick, bone, metal containers, illumination devices,
currency, footwear, tobacco, and lead balls, shot, and cartridge...
Introduction: Sports bras offer different levels of breast support and allow for a wide
range of vertical breast motion. Excessive breast motion during exercise causes
discomfort and may discourage participation in regular exercise. Inadequate breast
support may lead to adaptations in a woman's running mechanics. Purpose: This study
aimed to...
Experienced runners naturally optimize stride rate in a manner that minimizes oxygen uptake at given running speeds. However, as runners become fatigued, preferred stride rate often decreases. Whether such changes with fatigue occur in parallel with changes in optimal stride rate is unknown. This study's focus was on determining whether...
The purpose of this research was to explore the impact of finfish bycatch on the ocean shrimp Pandalus jordani fishery using two methods. One method looked at the breakage of the shrimp by finfish bycatch in the nets. The other looked at the impact of bycatch on fishing decisions. At-sea...
The Surgeon General of the United States in 2003 documented the existence of striking disparities for minorities and immigrants in mental health services and the underlying knowledge base. This thesis expands the knowledge base by examining the personal experiences and perspectives of community health workers (CHWs) employed in a mental...
This prioritization is designed to provide strategic focus for tidal wetland conservation and restoration actions undertaken in partnership with willing landowners. The study highlights land areas in the Smith River Watershed (within the Umpqua River estuary) where tidal wetland restoration or conservation action may offer the biggest ecological “bang for...
DNA damage, if not repaired, can become a mutation. Mutation
accumulation is associated with initiation and progression of tumorigenesis. DNA
mismatch repair (MMR) is required for maintaining genetic stability by repairing
replication errors. Biochemical studies have shown that MMR also recognizes
mismatch-causing DNA lesions, suggesting the role of MMR in...