T cell-dependent immune responses are highly sensitive to suppression by
exposure to the environmental contaminant 2,3,7,8-tetrachlorodibenzo-p-dioxin
(TCDD), yet direct effects of TCDD on T cells have been difficult to demonstrate.
Because the activation of naive T cells is initiated by dendritic cells (DC), the studies
presented in this dissertation were...
Golden paintbrush (Castilleja levisecta Greenman) historically inhabited the prairies of the Willamette Valley, Oregon. However, this Pacific Northwest endemic is currently restricted to eleven sites in the Puget Trough of Washington and British Columbia. Recovery criteria call for the establishment of new populations throughout the species historic range, including the...
End users create software when they use spreadsheet systems, web authoring tools and graphical languages, and when they create educational simulations, macros-by-demonstration, and dynamic e-business web applications and mash-ups. Some end-user developers, such as accountants or teachers, may have no formal training at all in programming. Others, such as scientists...
Although researchers have begun to explicitly support end-user programmers' debugging by providing information to help them find bugs, there is little research addressing the right content to communicate to these users. The specific semantic content of these debugging communications matters because, if the users are not actually seeking the information...