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Creator:: Jackson, Michael D.
Resource Type:: Dissertation
Full Text:: Streptolidine Moiety of Streptothricin F Abstract T. Mark Zabriskie Streptothricin F (STF, 12a) is a peptidyl

Creator:: Grochowski, Laura L.
Abstract:: Molecular genetic and enzymological techniques have been employed to study secondary metabolite biosynthesis. These investigations have focused on two projects: the cloning and heterologous expression of biosynthetic gene clusters from unculturable marine organisms and the characterization of individual enzymes involved in the biosynthesis of the antifungal agent blasticidin S. The...
Resource Type:: Dissertation
Full Text:: for Privacy ACKNOWLEDGEMENTS I would like to express gratitude to my advisor, Dr. Mark Zabriskie

Creator:: Blanchard, David, L.
Abstract:: L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs naturally in many organisms, including primates, as an intermediate in lysine degradation. The pathway by which lysine is converted into L-pipecolic acid employs the enzyme Lpipecolate oxidase (L-PO), and appears to be tissue specific to the central nervous system...
Resource Type:: Dissertation
Full Text:: T. Mark Zabriskie L-pipecolic acid (L-PA) is the higher homolog of proline. It occurs

Creator:: Fei, Xiaobo
Abstract:: Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. The nonproteinogenic amino acid capreomycidine is the signature residue found in the tuberactinomycin family of antitubercular peptide antibiotics and an important element of the pharmacophore. Recombinant VioG, a single module peptide synthetase from the viomycin gene cluster cloned...
Resource Type:: Masters Thesis
Full Text:: : _______________________________________________ T. Mark Zabriskie Molecular genetic and enzymological techniques have been employed to

Creator:: Kirkpatrick, Adam G.
Abstract:: Dental disease is a very prevalent and costly disease in which the symptoms, not the disease, are currently being treated. The disease is caused by pathogenic oral bacteria, many of which are a part of the Mutans Streptococci. The objective of this thesis was to find a natural substance that...
Resource Type:: Honors College Thesis
Full Text:: approved: ______________________________________________________ Mark Zabriskie Dental

Creator:: Tan, Ying
Abstract:: Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In this thesis, we studied the formation and modification of the nonproteinogenic amino acid enduracididine (End), which exists in two important antibiotics, mannopeptimycins (MPPs) and enduracidin. Sequence analysis of the MPP gene cluster revealed that the product of...
Resource Type:: Masters Thesis
Full Text:: approved: _______________________________________________ T. Mark Zabriskie

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