RNA structure prediction is a challenging problem, especially with pseudoknots. Recently, there has been a shift from the classical minimum free energy-based methods (MFE) to partition function-based ones that assemble structures based on base-pairing probabilities. Two typical examples of the latter group are the popular maximum expected accuracy (MEA) method...
Machine learning (ML) and deep learning (DL) models impact our daily lives with applications in natural language modeling, image analysis, healthcare, genomics, and bioinformatics. The exponential growth of biological sequence data necessitates accompanying advances in computational methods. Although deep learning is highly effective for detecting and classifying biological sequences, challenges...
As a general solution to the problem of managing structural and content variability in relational databases, in previous work we have introduced the Variational Database Management System (VDBMS). VDBMS consists of a representation of a variational database (VDB) and a corresponding typed query language (v-query). However, since this is a...
Newcomers’ seamless onboarding is important for open collaboration communi- ties, particularly those that leverage outsiders’ contributions to remain sustainable. Nevertheless, previous work shows that OSS newcomers often face several barriers to contribute, which lead them to lose motivation and even give up on contributing. A well-known way to help newcomers...
Although deep reinforcement learning agents have produced impressive results in many domains, their decision making is difficult to explain to humans. To address this problem, past work has mainly focused on explaining why an action was chosen in a given state. A different type of explanation that is useful is...
This thesis describes the implementation of ultrasonic sensors to trigger a stimulus to increase peer interaction for children with disabilities using modified ride-on-cars for mobility. Modified ride-on-car technology has improved mobility for children with disabilities by effectively replicating the social benefits of a powered mobility device, yet there are opportunities...
Recent studies have shown that novel continuous dropout methods can be viewed as a Bayesian interpretation of model parameters, though most such studies have shown results using normal distributions. As the posterior distributions over neural network nodes and parameters are intractable, given that they are a result of artificial construction...