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Filtering by: Creator Dickinson, Fred E. Remove constraint Creator: Dickinson, Fred E. Decade 2010-2019 Remove constraint Decade: 2010-2019 Degree Name Doctor of Philosophy (Ph.D.) Remove constraint Degree Name: Doctor of Philosophy (Ph.D.)

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  • Vitamin E and K interactions : investigating mechanisms of reduced vitamin K status in response to excess vitamin E

    Creator:
    Farley, Sherry Mae
    Abstract:
    The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
    Resource Type:
    Dissertation
    Full Text:
    November 12, 2012. Title: Vitamin E and K Interactions: Investigating Mechanisms of Reduced Vitamin K

  • Vitamin E and the alpha-tocopherol transfer protein during zebrafish embryogenesis

    Creator:
    Miller, Galen W.
    Abstract:
    Vitamin E was first described in 1922 as an unknown factor required for impregnated rats to carry their offspring to term. In fact, when vitamin E was chemically characterized it was given the name "tocopherol" derived from the Greek: tokos = childbirth; phero = to bear; and –ol, indicating an...
    Resource Type:
    Dissertation
    Full Text:
    May 4, 2012. Title: Vitamin E and the α-Tocopherol Transfer Protein During Zebrafish Embryogenesis

  • The role of the plasminogen activator system in the etiology of ovarian follicular cysts in dairy cattle

    Creator:
    McNeel, Anthony Kent
    Abstract:
    Cystic ovarian disease (COD) is an anovulatory condition in cattle that afflicts between 6-18% of all dairy cows in the US. Ovulation is dependent on the plasminogen activator (PA) family of proteases and protease inhibitor for proteolysis, culminating in follicular rupture. Failure of the follicle to ovulate suggests an aberration...
    Resource Type:
    Dissertation
    Full Text:
    regulates the proteolytic activity responsible for ovulation. Vitamin E supplementation reduces plasma

  • Application of modern NMR techniques to structure elucidation of bioactive natural products from tunicates

    Creator:
    Sikorska, Justyna
    Abstract:
    Recent developments in NMR hardware have extended the reach of natural products chemists to structure elucidation of compounds isolated on a nanomolar scale. In parallel with advances in hardware new NMR techniques for structure elucidation have evolved, e.g. quantitative NOEs, residual dipolar couplings (RDCs)and diffusion-ordered spectroscopy (DOSY). The application of...
    Resource Type:
    Dissertation
    Full Text:
    testing was given by Andrew M. Hau, Oliver B. Vining, Dr. Jane E. Ishmael and Dr. Aleksandra E. Sikora

  • In vivo detoxification of acetic acid in Saccharomyces cerevisiae

    Creator:
    Ding, Jun
    Abstract:
    The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
    Resource Type:
    Dissertation
    Full Text:
    Freitag, and Dr. Fred Stevens for their advice and help towards the completion of my program. Many

  • Chemical labeling methods and mass spectrometry of mitochondrial thiol proteomes

    Creator:
    Wang, Jing
    Abstract:
    Dysfunction of mitochondria has been linked to aging and the pathogenesis of many degenerative diseases. Aside from their primary function in energy production, mitochondria are considered as a major source and target of reactive oxygen and nitrogen species (ROS/RNS) in cells as well. The mitochondrial thiol proteome is a subset...
    Resource Type:
    Dissertation
    Full Text:
    , Fred Stevens, Ron Wrolstad and Gregory Rorrer. I would also like to express my appreciation to all

  • Durability Assessment of Wood Composites Using Fracture Mechanics

    Creator:
    Mirzaei, Babak
    Abstract:
    The advent of synthetic adhesives has transformed the structural applications of wood. However, a persistent issue in adhesively-bonded wood products has been moisture durability. When designing wood based composites, moisture durability will depend on both the wood phase and the adhesive phase. A key question, therefore, is how does one...
    Resource Type:
    Dissertation
    Full Text:
    ® and Georgia Pacific Chemicals® for donating materials to this project. Dr. Fred Kamke, Dr. Jamie

  • Material Expressions of Class, Status and Authority amongst Commissioned Officers at Fort Yamhill and Fort Hoskins, Oregon, 1856-1866

    Creator:
    Eichelberger, Justin E.
    Abstract:
    During the 19th century the United States Army was a military institution characterized by a hierarchical system of authoritative, social and economic inequality between members of its different military grades. Although necessary for insuring military discipline within the Army this system of inequality also influenced the non-military social lives of...
    Resource Type:
    Dissertation
    Full Text:
    AN ABSTRACT OF THE DISSERTATION OF Justin E. Eichelberger

  • Investigating Demographic and Evolutionary Factors Important for Fish Reintroduction

    Creator:
    Sard, Nicholas M.
    Abstract:
    Reintroduction programs are used to re-establish species back into their historical habitat. Most reintroduction programs have failed and few papers have evaluated factors that may be important to Pacific salmon. The 158 meter tall Cougar Dam has blocked Chinook salmon (Oncorhynchus tshawytscha) from accessing 40 kilometers of historical spawning and...
    Resource Type:
    Dissertation
    Full Text:
    committee members: William Ardren, David Noakes, Fred Allendorf, and Philip Brownell. As a young scientist

  • A role for ceramide accumulation in age-related cardiac mitochondrial dysfunction

    Creator:
    Monette, Jeffrey S.
    Abstract:
    Ceramides are a group of lipids in the sphingolipid family that are potent cell signaling molecules. Elevations in ceramide levels above the norm generally lead to apoptosis. Evidence from in vitro studies suggests that accumulation of ceramides within mitochondria leads to dysfunction of the mitochondria. This includes inhibition of the...
    Resource Type:
    Dissertation
    Full Text:
    like to thank the members of my graduate committee, Drs. Balz Frei, Joseph Beckman, J. Fred Stevens