Currently, the only anthrax vaccine licensed for human use in the United States is the Anthrax-vaccine-absorbed (AVA or Biothrax®). AVA suffers from several drawbacks, including a complicated and lengthy dosing schedule that requires six initial injections administered over eighteen months, followed by annual boosters. Therefore, a new generation anthrax vaccine...
Various applications like wireless UWB communication, fast data acquisition systems and digital storage oscilloscopes needs ADCs with instantaneous input signal bandwidth from 0.1-40 GigaHertz range with 6-10 bits of resolution -- a challenging task and an impressive goal to achieve. Flash ADCs have been conventionally employed to achieve these goals...
Digital Instrumentation and Detection is becoming the future of radiation detection and measurement. Computers are able to perform digitally what before would have taken an extensive array of analog equipment. The art of teaching radiation detection and measurement is following this same pattern of a shift from purely analog to...
Nonindigenous species are a major threat to the ecological integrity and biodiversity of marine and estuarine ecosystems. To become a successful invader, species must pass through four phases: (1) survive transport, (2) survive release, (3) establish a population, and (4) expand their range. To better understand these processes, an integrated...
Bicycle commuting is increasing in popularity due to exercise benefits, cost savings, and environmental concerns. Available specialized cycling apparel does not reflect the aesthetic and expressive needs of the bicycle commuter. Urban bicycle commuters need clothing that allows them to bicycle safely and effectively while maintaining their identity as professionals....
Stand structure in headwater riparian areas of western Oregon is highly variable making quantification of structural attributes within these stands difficult. A reliable sampling design is important to characterize and monitor changes in stand structure over time. This study examined sixteen alternatives for sampling live conifers and six alternatives for...
Proper nitrogen (N) management and variety selection are important for profitable hard red winter (HRW) wheat production in the dryland growing regions of northeastern Oregon. In these dryland systems, N management for grain yield and grain protein concentration (GPC) is challenging due to climatic and year-to-year variation in production environments....
The forest alpine tundra ecotone (FTE, also known as alpine treeline or subalpine parkland), is a conspicuous feature of mountain landscapes throughout the world. Climate change-driven increases in temperature are believed to result in FTE movement and tree invasion of subalpine meadows, which have been documented throughout the Northern Hemisphere...
Dramatic and ongoing changes pervading the Arctic and subarctic seas over
recent decades have motivated this effort to track and better understand hydrographic
variability using chemical tracers. Particular emphasis has been paid to differentiating
freshwater contributions to upper layers: namely Pacific water, meteoric water, and
sea-ice melt/formation.
Data collected in...
Computing agents require state information to make coherent and useful decisions. A state representation is a numerical translation of the environment and conditions that are pertinent factors in an agent's decision making. Although many representations, when paired with clever learning algorithms, are able to coordinate and capture prey in specific...
Summertime, wind-driven upwelling off the Oregon coast delivers nutrient rich water to the surface that fuels the autotrophic production of particulate organic carbon (POC). This POC can be transported horizontally by fluid motions and vertically by sinking to the bottom where it can be entrained in the benthic boundary layer...
The Clean Water Act imposes Total Maximum Daily Load (TMDL) limits on pollutant concentrations within wastewater effluent; in Oregon, thermal discharge is one of the pollutants subject to regulation. The City of Woodburn, Oregon, funded a series of pilot scale studies to investigate the utility of natural systems to reduce...
Feeding conjugated linoleic acids (CLA) improves reproductive performance in dairy cows; however, the molecular mechanisms by which CLA improves reproduction are not well understood. Therefore, we evaluated whether the CLA isomers, trans-10, cis-12 CLA and cis-9, trans-11 CLA altered synthesis of steroidogenic hormones in bovine luteal cells by measuring concentrations...
Llamas (Lama glama) appear to have predisposing anatomical features for developing
otitis media such as a long and narrow external acoustic meatus and a trabecular
tympanic bulla. However, there is limited information available about the morphology of
the ear in this species. The aim of this study was to evaluate...
This dissertation describes the application and development of molecular tools that have great potential for use in studying variation in strawberry germplasm. The first study evaluated 91 microsatellite (simple sequence repeat, SSR) markers for transferability in 22 Fragaria species and their utility in fingerprinting octoploid strawberries. Out of the transferable...
One of the most common practices regarding estimation of forest attributes is
the partitioning of large forested subpopulations into smaller areas of interest to
coincide with specific objectives of present and future forest management. New
estimators are needed to improve estimation of selected forest attributes in small areas
where the...
Stripe rust (Puccinia striiformis f. sp. tritici) has been receiving
increased attention in the USA since the appearance of more virulent races
detected in the past decade. These races caused yield losses even in areas
where the disease previously was rarely detected. Host plant resistance is the
most cost effective...
The overall goal of this project was to design a wood frame shear wall that could withstand greater displacement before damage occurred to the Gypsum Wall Board (GWB). More specifically, the objectives of the study were: (1) to evaluate damage to the GWB in alternative shear wall designs at 1%,...
This thesis is comprised of two manuscripts based on a laboratory experiment conducted to examine realistic wave forcing on a vertical wall subjected to tsunami loading. The first manuscript examined tsunami force and pressure distributions on a rigid wall that was fronted by a small seawall. Six different seawall heights...
This thesis presents an approach to develop innovative methods for decontamination and surface protection applicable to naval nuclear ships and potentially, personnel, replacing antiquated techniques. To accomplish this goal, two products manufactured by CBI Polymers, LLC., DeconGel™ 1101 (1101) and a shampoo, DeconGel™ "prototype" (prototype), were tested.
The prototype was...
Seasonal wetlands in arid and semi-arid lands provide an important source of surface water in otherwise dry lands. Central Oregon's high desert, located in the Northern Great Basin (NGB) is dotted with hundreds of seasonal pools, locally called playas. The playas hold water or snow during parts of winter and...
This dissertation presents a research series demonstrating the use of pharmacokinetic modeling and simulations as tools to assess drug concentration and disposition in patient populations. For drugs requiring therapeutic drug monitoring, these tools are necessary to ensure patients are receiving a safe and effective dose of medication to address their...
This paper provides a measurement-based performance evaluation of the Optimized Link State Routing (OLSR) protocol. Two versions of OLSR, OLSR-ETX and OLSR-ETT, are implemented and evaluated on a mesh network that we built from off-the-shelf commercial components. OLSR-ETX uses the Expected Transmission Count (ETX) metric whereas, OLSR-ETT uses the Expected...
This dissertation outlines two approaches for improving the efficiency and reducing the cost of photovoltaic energy generation. First, the structures of known binary copper and iron compounds are used to choose the promising compositions Fe₂XS₄ (X = Si, Ge), Cu₃TaQ₄ (Q = Se, Te), and BaCuQ'F (Q' = S, Se,...
This research sought to explore the implications of different tenure regimes for both
landscape-level ecological processes and the overall resilience of a social-ecological
system in Central Oregon. The purchase by an investor of former industrial timberlands
known as the Bull Springs tract raised the specter of dispersed residential development on...
The number of endangered species is rapidly increasing while paucity of adequate information and resources delays establishment of conservation actions. The IUCN’s listing system is insufficient to determine conservation priorities and many species lack information even to be evaluated (i.e., “data deficient”). Here I proposed and tested the Rapid Endangered...
Met is a prognostic indicator of colorectal cancer patient survival. Therapies that target Met may therefore have beneficial outcomes in the clinic. Recently, EGCG was reported to suppress Met activation, although the mechanisms were not elucidated. HCT116 and HT29 human colon cancer cells were used to examine the relationships between...
Transient liquid-phase diffusion brazing is used in precision, hermetic joining applications as a replacement for diffusion bonding to reduce cycle times, reduce bonding pressure and improve yields. Studies showed that the interlayer used in diffusion brazing can be detrimental due to the use of melting point depressants (MPDs). The goal...
Depleted species of rockfish (Sebastes spp.) from the Northeast Pacific experience high discard mortality due to "barotrauma," induced from the rapid change in pressure during capture. Research suggests rockfish have the potential to survive barotrauma if immediately recompressed, but the potential for long-term recovery is unknown. In this project, we...
The primary objective of this research was to determine if native species within the genera Castilleja and Pedicularis are naturally infected by white pine blister rust (Cronartium ribicola) in whitebark pine ecosystems of the Oregon and Washington Cascade Range. Secondary objectives were to monitor the phenology of aecial and telial...
Corporate social responsibility (CSR) can be defined as companies acting in accordance with societal demands. In recent years, CSR has gradually become a leading issue in business. Heightened corporate attention to CSR has not been entirely voluntary. Many companies awoke to it only after being surprised by public response to...
Little, if any, quantifications have been made on the contribution of the vertebral column during jumping in quadrupedal mammals. Previous studies of jumpers have focused on the morphological and physiological specializations of the hindlimbs. In this study, such specialization was measured during the supramaximal jumps of the Pacific jumping mouse...
In this thesis, I examine composition scholarship on the intersections of religious faith and writing pedagogy over the past twenty years, tracing the origins of compositionists' discomfort with religion and focusing on pedagogical approaches for working with religiously-committed students. In particular, I emphasize the way in which these approaches are...
Concern over the increasing proportion of juvenile wood grown in second growth plantations has led to a large amount of research on the effects of common silvicultural practices on wood quality. Lacking is research on the effect of timing and
duration of vegetation control on wood quality near the pith...
The development of micro total analysis systems (µTAS), also called “lab-on-a-chip”, or microfluidic analysis systems, is presented in this dissertation. Various research areas, covering subjects from magnetic particles synthesis to novel microchip fabrication techniques, are explored to develop a lab-on-a-chip system capable of performing magnetic bead-based bioassays. These devices are...
Large areas of non-coniferous communities in southwestern Oregon are thinned to reduce fire hazard and accomplish ecosystem restoration, under the assumption that current fuel loads are unnaturally high. Although Oregon white oak (Quercus garryana) woodlands are a characteristic landscape component in this region, little is known about their current or...
Massive die-offs of Bufo bufo gargarizans were observed in May 2008 in Mangwal
Gee, Korea. To find out the causes for this disaster several different elements
were examined: pH, total nitrogen, dissolved oxygen (DO), and dissolved heavy
metal, suspension, introduced species, habitat change, disease, temperature
changes, and precipitation and humidity....
Phenolic compounds are known to have biological activity with beneficial effects on human health. Fruit of cultivated tomatoes (Solanum lycopersicum L.) are a major source of phenolics in the U.S. diet because this crop is the second most consumed vegetable per capita, but actual levels are low compared to other...
A relatively new model of error control is the limited magnitude error over high radix channels. In this error model, the error magnitude does not exceed a certain limit known beforehand. In this dissertation, we study systematic error control codes for common channels under the assumption that the maximum error...
A proposed state-and-transition model (STM) for the Deep Sand Savannah ecological site in central New Mexico was developed using historical data and expert knowledge. This STM was tested utilizing data from short and long term one-seed juniper (Juniperus monosperma (Engelm.) Sarg.) control experiments initiated in 1981 and 1985. Utilizing data...
This thesis explores open questions regarding molecular forms and interactions of natural and synthetic aromatic compounds present in soils and sediments.
Plant biomass-derived black carbon (biochar) generated through incomplete natural and anthropogenic combustion processes is a major source of aromaticity in terrestrial ecosystems. Chapter one represents a detailed account of...
The objective of this thesis is to provide an initial demonstration of two-terminal and three-terminal electronic devices employing amorphous multi-component metallic film
(AMMF) electrodes. Such a demonstration is successfully achieved in the fabrication of metal-insulator-metal (MIM) diode and hot electron transistor (HETs) structures employing ZrCuAlNi AMMF electrodes. The ultra-smooth surface...
This dissertation presents an incremental analog-to-digital converter (ADC) with digital digital-to-analog converter (DAC) mismatch correction. A theoretical time-domain analysis technique was developed to predict the noise performance of the incremental ADC, and a new optimization technique was proposed to minimize the output noise.
In the calibration mode, the incremental ADC...
The objective of this project was to develop an analytical model of a light-framed wood structure using a prevalent structural analysis computer program in order to evaluate system effects and define load paths within the structure, especially under extreme wind events. Simplified modeling techniques and material definitions were developed and...
Modern day digital systems employ frequency
synthesizers to provide a common clock to the system.
They are undergoing large scale integration due to which, mitigation
of the effect of noise on power supply has become a major design consideration
in clocking circuits. Rapid scaling of CMOS technology mandates the
design...