Obesity is achieved at the point where fat accumulation begins to exert deleterious effects on an organism. The human body accrues fat when there is an energy imbalance occurring, where caloric intake exceeds expenditure.Many anti-obesity drugs used in the past have had undesirable side effects, and currently there is a...
As scientific technologies and techniques have improved in past decades, it has become
possible to quickly collect unprecedented quantities of experimental data. In the study of gene expression, for instance, datasets comprising tens of thousands of variables and hundreds of treatments can be produced in a matter of months. When...
Modifications of histone tail amino acid residues are necessary for many reactions involving chromatin. These processes can produce transcriptionally active, euchromatic, or inactive, heterochromatic, segments of DNA. The formation and maintenance of facultative heterochromatin is critical for the proper growth and development of many eukaryotes. Euchromatin can be changed into...
Abstract
Understanding the effects of climate change on forest ecosystems requires exploration of the relationships of different components of the system, such as the response of biota to local hydrology, temperature, precipitation, and elevation. The Long-term Ecological Research Program at the H. J. Andrews Experimental Forest, located in the Western...
Humans and rodents experience declines in reference (long-term) and working (short-term)
memory and cognitive flexibility during the aging process. Aging changes in GluN1 and
GluN2B subunits of N-methyl-D-aspartate (NMDA) receptors show a relationship to both
reference and working memory deficits. Sulindac, an anti-inflammatory drug, enhances working memory and NMDA receptor...
A pro-inflammatory agent, lipopolysaccharide, can mimic the effects of aging on spatial reference memory
E. R. ESCOBEDO and K. R. Magnusson, Dept. of Biomedical Sciences, Coll. of Vet. Med., Linus Pauling Institute, Oregon State University, Corvallis, OR 97331
Humans and rodents experience declines in reference (long-term), working (short-term) memory, and...
Lung cancer in humans is an adult-onset disease. It is the number one cause of cancer mortality for both men and women and has a poor (15%) survival rate. Biological markers of the disease would allow for early diagnosis and treatment. The specific aims of this research project were to...
As part of the Botswana Global Learning Internship Program, a qualitative study was conducted regarding the current staffing conditions at the local village health clinic in Maunatlala, Botswana. This was a month-long project conducted over the summer of 2018. Students from Oregon State University lived in the village of Maunatlala...
Succinate dehydrogenase (Sdh) inhibitor fungicides, such as boscalid, are effective for the management of gray mold caused by the fungal pathogen Botrytis cinerea. Unfortunately, resistance to boscalid was common among isolates of the pathogen from small fruits grown in Oregon. Boscalid-resistance is commonly associated with mutations in Sdh, especially in...
Spotted wing drosophila, Drosophila suzukii, is a recently introduced, invasive pest in Oregon. It oviposits in near-mature and mature fruit, and thus is an important concern for the small fruit industry. A crop consultant observed that mature raspberry fruit with D. suzukii larvae do not show symptoms of molds as...