Background: Clostridium difficile is the main cause of nosocomial infections including antibiotic associated diarrhea, pseudomembranous colitis and toxic megacolon. During the course of Clostridium difficile infections (CDI), C. difficile undergoes sporulation and releases spores to the colonic environment. The elevated relapse rates of CDI suggest that C. difficile spores has...
The use of in situ measurements is essential in the validation and evaluation of the algorithms that provide coastal water quality data products from ocean colour satellite remote sensing. Over the past decade, various types of ocean colour algorithms have been developed to deal with the optical complexity of coastal...
Coibamide A is an N-methyl-stabilized depsipeptide that was isolated from a marine cyanobacterium as part of an International Cooperative Biodiversity Groups (ICBG) program based in Panama. Previous testing of coibamide A in the NCI in vitro 60 cancer cell line panel revealed a potent anti-proliferative response and "COMPARE-negative" profile indicative...
Rapamycin (Rapa) and dietary restriction (DR) have consistently
been shown to increase lifespan. To investigate whether Rapa
and DR affect similar pathways in mice, we compared the effects
of feeding mice ad libitum (AL), Rapa, DR, or a combination of
Rapa and DR (Rapa + DR) on the transcriptome and...
Sediments associated with hydrothermal venting, methane seepage and large organic falls such as whale, wood and plant detritus create deep-sea networks of soft-sediment habitats fueled, at least in part, by the oxidation of reduced chemicals. Biological studies at deep-sea vents, seeps and organic falls have looked at macrofaunal taxa, but...
In some cases a canopy height model (CHM) is the only available source of forest height information. For these cases it is important to understand the predictive power of CHM data for forest attributes. In this study we examined the use of lidar-derived CHM metrics to predict forest structure classes...
Mycobacteriosis is a common disease of laboratory zebrafish Danio rerio. Different infection patterns occur in zebrafish depending on mycobacterial species. Mycobacterium marinum and M. haemophilum produce virulent infections associated with high mortality, whereas M. chelonae is more widespread and is not associated with high mortality. Identification of mycobacterial infections to...
Nitrosomonas sp. Is79 is a chemolithoautotrophic ammonia-oxidizing bacterium that belongs to the family Nitrosomonadaceae within the phylum Proteobacteria. Ammonia oxidation is the first step of nitrification, an important process in the global nitrogen cycle ultimately resulting in the production of nitrate. Nitrosomonas sp. Is79 is an ammonia oxidizer of high...
Network theory is applied to an array of streamflow
gauges located in the Coast Mountains of British
Columbia (BC) and Yukon, Canada. The goal of the analysis
is to assess whether insights from this branch of mathematical
graph theory can be meaningfully applied to hydrometric
data, and, more specifically, whether...
Network theory is applied to an array of streamflow gauges located in the Coast Mountains of British Columbia and Yukon, Canada. The goal of the analysis is to assess whether insights from this branch of mathematical graph theory can be meaningfully applied to hydrometric data, and more specifically, whether it...
Users interested in customizing their Primo installation are required to configure specific settings, files, and code during the View setup process. A consequence of this is that unique customizations are not easily sharable between institutions. With the release of the new Primo User Interface, Ex Libris has enabled institutions to...
Hydrology is the main environmental filter in aquatic ecosystems and may result in shared tolerances and functional traits among species in disparate ecosystems. We analyzed the associations between taxonomic and functional facets of diversity within aquatic ecosystems (ponds vs. streams) across a hydroperiod gradient (1–365 d) to untangle the hydrologic...
This study was interested in determining whether vocal communications or facial expressions and body language are more effective in communicating positive, neutral or negative affects when used in isolation and without deception. A sample of six male and six female (n = 12) students in Dr. Bernieri’s Winter term 2016...
The New Zealand endemic Maui’s dolphin Cephalorhynchus hectori maui is characterized by several life history traits thought to be important predictors of extinction risk in marine mammals, including a slow rate of reproduction, small geographic range, small group size, and coastal distribution. We continued the genetic monitoring of the remnant...
Background: COUP-TF interacting protein 2 [(Ctip2), also known as Bcl11b] is an important regulator of skin homeostasis, and is overexpressed in head and neck cancer. Ctip2(ep-/-) mice, selectively ablated for Ctip2 in epidermal keratinocytes, exhibited impaired terminal differentiation and delayed epidermal permeability barrier (EPB) establishment during development, similar to what...
The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
Measuring surface fluxes using the surface renewal (SR) method requires a set of programmatic algorithms for tabulation, algebraic calculation, and quality control. Full matlab scripts and functions, example data used in the analysis, and results are included in this data archive. Because the SR method utilizes high frequency (20-100 Hz+)...
Climate-induced changes may be more substantial within the marine environment, where following ecological change is logistically difficult, and typically expensive. As marine animals tend to produce stereotyped, long-range signals, they are ideal for repeatable surveying. In this study we illustrate the potential for calling rates to be used as a...
Direct demographic density dependence is necessary for population regulation and is a central concept in ecology, yet has not been studied in many invasive species, including any invasive marine fish. The red lionfish (Pterois volitans) is an invasive predatory marine fish that is undergoing exponential population growth throughout the tropical...
Macromoth diversity, abundance, and community structure in the topographically complex HJ Andrews Experimental Forest and LTER site was studied on the west slope of the Cascade Range, Oregon. Data on 493 macromoth species (62,221 individuals) was sampled eight times/year at 20 locations from 2004 to 2008 and examined using multivariate...
Metamorphosis is often characterized by profound changes in morphology and physiology that can affect the dynamics of species interactions. For example, the interaction between a pathogen and its host may differ depending on the life stage of the host or pathogen. One pathogen that infects hosts with complex life cycles...
The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Submersible pressure transducers have been utilized
for collecting water level data since the early 1960s.
Together with a digital data logger, it is a convenient way
to record water level fluctuations for long-term monitoring.
Despite the wide use of pressure transducers for water level
monitoring, little has been reported regarding...
Submersible pressure transducers have been utilized for collecting water level data since early 1960s. Together with a digital datalogger, it is a convenient way to record water level fluctuations for long-term monitoring. Despite the widely use of pressure transducers for water level monitoring, little has been reported for their accuracy...
Although there is acute concern that insect-caused tree mortality increases the likelihood or severity of subsequent wildfire, previous studies have been mixed, with findings typically based on stand-scale simulations or individual events. This study investigates landscape- and regional-scale wildfire likelihood following outbreaks of the two most prevalent native insect pests...
Although there is acute concern that insect‐caused tree mortality increases the likelihood or severity of subsequent wildfire, previous studies have been mixed, with findings typically based on stand‐scale simulations or individual events. This study investigates landscape‐ and regional‐scale wildfire likelihood following outbreaks of the two most prevalent native insect pests...
Although there is acute concern that insect‐caused tree mortality increases the likelihood or severity of subsequent wildfire, previous studies have been mixed, with findings typically based on stand‐scale simulations or individual events. This study investigates landscape‐ and regional‐scale wildfire likelihood following outbreaks of the two most prevalent native insect pests...
We examined the multivariate life-history trajectories of age 0 and age 1 female Gambusia affinis to determine relative effects of age-based and environment-based cues on reproductive investment. Age 0 females decreased reproductive investment prior to the onset of fall and winter months, while age 1 females increased reproductive investment as...
Selenium (Se) is an essential micronutrient in cattle, and Se-deficiency can affect morbidity and mortality. Calves may have greater Se requirements during periods of stress, such as during the transitional period between weaning and movement to a feedlot. Previously, we showed that feeding Se-fertilized forage increases whole-blood (WB) Se concentrations...
Resistance of the snail Biomphalaria glabrata to the trematode Schistosoma mansoni is correlated with allelic variation at copper-zinc superoxide dismutase (sod1). We tested whether there is a fitness cost associated with carrying the most resistant allele in three outbred laboratory populations of snails. These three populations were derived from the...
“Substituent effects” is an important and useful concept in organic chemistry. Although there are many approaches to parametrizing the electronic and steric effects of substituents, the physical basis for the parameters is often unclear. The purpose of the present work is to explore the properties of chemical shifts in carbon...
Differences in the chemical composition of calcified skeletal structures (e.g. shells, otoliths) have proven useful for reconstructing the environmental history of many marine species. However, the extent to which ambient environmental conditions can be inferred from the elemental signatures within the vertebrae of elasmobranchs (sharks, skates, rays) has not been...
Physical mapping and genome sequencing are underway for the ≈17 Gb wheat genome. Physical mapping methods independent of meiotic recombination, such as radiation hybrid (RH) mapping, will aid precise anchoring of BAC contigs in the large regions of suppressed recombination in Triticeae genomes. Reports of endosperm development following pollination with...
Previous research has suggested that the use of more authentic learning activities can produce more robust and durable knowledge gains. This is consistent with calls within civil engineering education, specifically hydrology, that suggest that curricula should more often include professional perspective and data analysis skills to better develop the "T-shaped"...
Previous research has suggested that the use of more authentic learning activities can produce more robust and durable knowledge gains. This is consistent with calls within civil engineering education, specifically hydrology, that suggest that curricula should more often include professional perspective and data analysis skills to better develop the ‘T-shaped’...
Spider wasps had long been proposed to originate in the mid-Cretaceous based on the Burmese amber fossil Bryopompilus interfector Engel and Grimaldi, 2006. We performed a morphological examination of this fossil and determined it does not belong to Pompilidae or any other described hymenopteran family. Instead, we place it in...
The exponential growth of the salmonid farming industry during the last 3 decades has created conditions for massive escapes of these exotic species into natural environments in southern Chile. Here, we review and update information about salmonid escapes from 1993 to 2012 and examine their potential environmental, social, and economic...
Heterotrophic respiration (HR), the aerobic and anaerobic processes mineralizing organic matter, is a key carbon flux but one impossible to measure at scales significantly larger than small experimental plots. This impedes our ability to understand carbon and nutrient cycles, benchmark models, or reliably upscale point measurements. Given that a new...
The estimation of the economic status of individuals and their households is central to much work in epidemiology and the social sciences. Wealth is a key determinant of health and social achievement and an indicator of well-being in its own right. For this reason, the development and testing of novel...
Genetic-modification strategies are currently being developed to reduce the transmission of vector-borne diseases, including African trypanosomiasis. For tsetse, the vector of African trypanosomiasis, a paratransgenic strategy is being considered: this approach involves modification of the commensal symbiotic bacteria Sodalis to express trypanosome-resistance-conferring products. Modified Sodalis can then be driven into...
The development of hybrids with enhanced expression of heterosis depends on the genetic background of the source population and the effectiveness of a breeding scheme used to identify and use divergent inbred lines with good combining ability. The present study was conducted to examine the potential of improved tropical reciprocal...
Earth system processes exhibit complex patterns across time, as do the models that seek to replicate these processes. Model output may or may not be significantly related to observations at different times and on different frequencies. Conventional model diagnostics provide an aggregate view of model–data agreement, but usually do not...
We evaluate the return on investment (ROI) from public land conservation in the state of Minnesota, USA. We use a spatially-explicit modeling tool, the Integrated Valuation of Ecosystem Services and Tradeoffs (InVEST), to estimate how changes in land use and land cover (LULC), including public land acquisitions for conservation, influence...
Ecosystem process models are important tools for determining the interactive effects of global change and disturbance on forest carbon dynamics. Here we evaluated and improved terrestrial carbon cycling simulated by the Community Land Model (CLM4), the land model portion of the Community Earth System Model (CESM1.0.4). Our analysis was conducted...
Interannual variability in salmon (Oncorhynchus spp.) production in the northeast Pacific is understood to be driven by oceanographic variability and bottom-up processes affecting prey availability to juvenile salmon. Scyphozoan jellyfish have an important role in shaping the pathways of energy flow through pelagic food webs. While jellyfish obtain high production...
We explored the relationship between relaxed selection, oxidative stress, and spontaneous mutation in a set of mutation-accumulation (MA) lines of the nematode Caenorhabditis elegans and in their common ancestor. We measured steady-state levels of free radicals and oxidatively damaged guanosine nucleosides in the somatic tissues of five MA lines for...
We live in an exciting time for biology. Technological advances have made data collection easier and cheaper than we could ever have imagined just 10 years ago. We can now synthesize and analyze large data sets containing genomes, transcriptomes, proteomes, and multivariate phenotypes. At the same time, society's need for...
Concrete is certainly prone to internal deteriorations or defects during the construction and operating periods. Compared with other nondestructive techniques, infrared thermography can easily detect the subsurface delamination in a very short period of time, but accurately identifying its size and depth in concrete is a very challenging task. In...
To survive winter, many perennial plants become endodormant, a state of suspended growth maintained even in favorable growing environments. To understand vegetative bud endodormancy, we collected paradormant, endodormant, and ecodormant axillary buds from Populus trees growing under natural conditions. Of 44,441 Populus gene models analyzed using NimbleGen microarrays, we found...
Conservation of wildlife depends on an understanding of the interactions between animal movements and key landscape factors. Habitat requirements of wide-ranging species often vary spatially, but quantitative assessment of variation among replicated studies at multiple sites is rare. We investigated patterns of space use for 10 populations of two closely...