Hepatocellular carcinoma (HCC) is currently one of the top lethal cancers with an increasing trend. Deregulation of MYC in HCC is frequently detected and always correlated with poor prognosis. As the zebrafish genome contains two differentially expressed zebrafish myc orthologs, myca and mycb, it remains unclear about the oncogenicity of...
Here we report a new transgenic expression system by combination of liver-specific expression, mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure of mifepristone to induce permanent genomic recombination mediated by...
Because Ras signaling is frequently activated by major hepatocellular carcinoma etiological factors, a transgenic zebrafish constitutively expressing the kras(V12) oncogene in the liver was previously generated by our laboratory. Although this model depicted and uncovered the conservation between zebrafish and human liver tumorigenesis, the low tumor incidence and early mortality...
Human liver cancer is one of the deadliest cancers worldwide, with hepatocellular carcinoma (HCC) being the most common type. Aberrant Ras signaling has been implicated in the development and progression of human HCC, but a complete understanding of the molecular mechanisms of this protein in hepatocarcinogenesis remains elusive. In this...
The production and distribution of fish products in Vietnam have been faced with strict consumer requirements such as seafood quality, hygiene, safety standards, traceability, environmentally friendly manufacturing and fisheries resource conservation. These are compulsory requirements for sustainable business development in international markets. The research applies the Structure – Conduct –...
Ben Tre, located on the Tien Delta Triangle--with a coastline of 65 km and the 20,000 km2
Exclusive Economic Zone--is one of the Mekong Delta’s 13 provinces. Given both its vast
access to coastline and the EEZ, fisheries is one of the Ben Tre’s key economic sectors. This
study specifies...
Pangasius culture in recent years has proved its ability to contribute to national wealth and prosperity. As far as domestic consumption is concerned, pangasius represents an important source of nutrient intake for a large portion of the population. Multiple effects have been generated through large-scale exports, which is associated with...
Ocean health is a major concern for coastal communities dependent on the ocean for their livelihood. Recent changes in in ocean health force researchers to examine the factors that influence the decline in ocean health. The paper developed production functions using the Global Ocean Health Index (OHI) for 2014 and...
Proceedings of the Eighteenth Biennial Conference of the International Institute of Fisheries Economics and Trade, held July 11-15, 2016 at Aberdeen Exhibition and Conference Center (AECC), Aberdeen, Scotland, UK.
Proceedings of the Eighteenth Biennial Conference of the International Institute of Fisheries Economics and Trade, held July 11-15, 2016 at Aberdeen Exhibition and Conference Center (AECC), Aberdeen, Scotland, UK.