Index Catalog // ScholarsArchive@OSU

Identification of Novel Biomarkers in urine from Canine Transitional Cell Carcinoma Patients

Creator:: Pope, George, Yang, Liping, Goodall, Cheri, Schlueter, Andrew, and Bracha, Shay
Abstract:: • Bladder Cancer in the United States has progressively been one of the more common cancers and is estimated to have 74,000 new cases as well as 16,000 deaths in 2015.1 • This type of cancer also has one of the highest rates of recurrence with an average of 60%...
Resource Type:: Poster
Full Text:: ., Milovancev, M., Medlock, J., Goodall, C., ... & Maier, C. S. (2014). A multiplex biomarker approach for the

The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line

Creator:: Bracha, Shay, Viall, Austin, Goodall, Cheri, Stang, Bernadette, Ruaux, Craig, Seguin, Bernard, and Chappell, Patrick E.
Abstract:: BACKGROUND: The significance of the serotonergic system in bone physiology and, more specifically, the importance of the five hydroxytryptamine receptor 2A (5HTR2A) in normal osteoblast proliferation have been previously described; however the role of serotonin in osteosarcoma remains unclear. Particularly, the expression and function of 5HTR2A in canine osteosarcoma has...
Resource Type:: Article
Full Text:: *, Austin Viall1, Cheri Goodall1, Bernadette Stang1, Craig Ruaux1, Bernard Seguin3 and Patrick E Chappell2

Antiproliferative effects of masitinib and imatinib against canine oral fibrosarcoma in vitro

Creator:: Milovancev, Milan, Helfand, Stuart C., Marley, Kevin, Goodall, Cheri P., Löhr, Christiane V., and Bracha, Shay
Abstract:: Background: Canine oral fibrosarcoma (COF) is one of the most common oral tumors in dogs and carries a guarded prognosis due to a lack of effective systemic therapeutic options. Mastinib and imatinib are two commonly used tyrosine kinase inhibitors (TKIs) in veterinary oncology but their potential efficacy against COF is...
Resource Type:: Article
Full Text:: *, Stuart C. Helfand1, Kevin Marley1, Cheri P. Goodall1, Christiane V. Löhr2 and Shay Bracha1 Abstract

Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts

Creator:: Milovancev, Milan, Hilgart-Martiszus, Ian, McNamara, Michael J., Goodall, Cheri P., Seguin, Bernard, Bracha, Shay, and Wickramasekara, Samanthi I.
Abstract:: Background: Osteosarcoma (OSA) is the most common primary bone tumor of dogs and carries a poor prognosis despite aggressive treatment. An improved understanding of the biology of OSA is critically needed to allow for development of novel diagnostic, prognostic, and therapeutic tools. The surface-exposed proteome (SEP) of a cancerous cell...
Resource Type:: Article
Full Text:: osteoblasts Milan Milovancev1*, Ian Hilgart-Martiszus1, Michael J McNamara2, Cheri P Goodall1, Bernard

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Creator:: Bracha, Shay, McNamara, Michael, Hilgart, Ian, Milovancev, Milan, Medlock, Jan, Goodall, Cheri, Wickramasekara, Samanthi, and Maier, Claudia S.
Abstract:: Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome...
Resource Type:: Article

Advanced Mass Spectrometry Techniques for Characterizations of Proteome and Lipidome Profiles of Osteosarcoma Cells

Creator:: Song, Zifeng
Abstract:: Mass Spectrometry has emerged as an analytical core technique in omics sciences, in particularly mass spectrometry has advanced the fields of proteomics, metabolomics and lipidomics in recent years. Mass spectrometric techniques have enabled the characterization and determination of abundance levels of a wide range of biomolecules at molecular and system-wide...
Resource Type:: Dissertation

Loss of rhythmic circadian clock gene expression is associated with decreases in estrogen receptor expression in canine mammary cancer

Creator:: Hughes, Kelly L.
Abstract:: The endogenous circadian clock is an intracellular transcriptional feedback loop timing daily patterns of multiple biological rhythms within a 24-hour period. Disturbance in various rhythms leads to alteration of normal biological processes including cellular proliferation and tumor suppression. Endogenous circadian clock rhythms have been found to be disrupted in breast...
Resource Type:: Masters Thesis
Full Text:: Bracha, and Cheri Peyton Goodall, for their assistance and guidance in the laboratory, sample

The effect of Blastocystis sp. ST1 on the expression of serotonin transporter,tryptophan hydroxylase, toll-like receptor 2, and toll-like receptor 4 in CACO-2 cellculture

Creator:: Lawrence, Yuri Alexander, 1980-
Abstract:: Blastocystis spp. is a common intestinal parasite in humans and animals that has been associated with acute or chronic digestive disorders such as irritable bowel syndrome. Serotonin mediates intestinal motility, sensation, and secretory function in the normal intestinal tract. Serotonin (5-HT) signaling is decreased in animal models of colitis, as...
Resource Type:: Masters Thesis
Full Text:: . Bernadette Stang, Ms. Cheri Goodall, and Dr. Kevin Marley for their technical assistance and expertise

Exploring reproductive signaling using nonconventional aquatic models : Aging and reproductive function in killifish and sea anemones

Creator:: Ferguson, Lindsey G.
Abstract:: Aquatic animals possess surprising similarities to humans in reproductive signaling that are simplified or elaborated for life underwater, making them useful for studying reproductive control. In this thesis, killifish and sea anemones are used as models for reproductive function and aging. The aging model Nothobranchius (killifish) was used to investigate...
Resource Type:: Honors College Thesis
Full Text:: his microscopes. Thank you also to Cheri Goodall and Cammie Crowder for their knowledge and guidance

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Canine Transitional Cell Carcinoma and Its Correlation with Cyclooxygenase-2 Expression

Creator:: Weinman, Marcus Andrew
Abstract:: Canine transitional cell carcinoma (TCC) has been shown to have a substantial inflammatory component. It exhibits genotypic and morphologic elements that resemble its human counterpart. Cyclooxygenases (COX) are key enzymes in the synthesis of proinflammatory molecules, such as prostaglandins. Excess prostaglandin production through cyclooxygenases may promote oncogenesis and progression of...
Resource Type:: Honors College Thesis
Full Text:: advance my learning, both in her lab and in others. I’d like to give special thanks to Cheri Goodall

ScholarsArchive@OSU

Identification of Novel Biomarkers in urine from Canine Transitional Cell Carcinoma Patients

The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line

Antiproliferative effects of masitinib and imatinib against canine oral fibrosarcoma in vitro

Comparative analysis of the surface exposed proteome of two canine osteosarcoma cell lines and normal canine osteoblasts

A Multiplex Biomarker Approach for the Diagnosis of Transitional Cell Carcinoma from Canine Urine

Advanced Mass Spectrometry Techniques for Characterizations of Proteome and Lipidome Profiles of Osteosarcoma Cells

Loss of rhythmic circadian clock gene expression is associated with decreases in estrogen receptor expression in canine mammary cancer

The effect of Blastocystis sp. ST1 on the expression of serotonin transporter,tryptophan hydroxylase, toll-like receptor 2, and toll-like receptor 4 in CACO-2 cellculture

Exploring reproductive signaling using nonconventional aquatic models : Aging and reproductive function in killifish and sea anemones

The Effect of Non-Steroidal Anti-Inflammatory Drugs on Canine Transitional Cell Carcinoma and Its Correlation with Cyclooxygenase-2 Expression

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