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Filtering by: Creator Kaur, Hardeep Decade 2010-2019

Modification of Rifamycin Polyketide Backbone Leads to Improved Drug Activity Against Rifampicin-Resistant Mycobacterium tuberculosis

Creator:

Nigam, Aeshna, Almabruk, Khaled H., Saxena, Anjali, Yang, Jongtae, Mukherjee, Udita, Kaur, Hardeep, Kohli, Puneet, Kumari, Rashmi, Singh, Priya, Zakharov, Lev N., Singh, Yogendra, Mahmud, Taifo, and Lal, Rup

Abstract:

Rifamycin B, a product of Amycolatopsis mediterranei S699, is the precursor of clinically used antibiotics that are effective against tuberculosis, leprosy and AIDS related mycobacterial infections. However, prolonged usage of these antibiotics has resulted in the emergence of rifamycin resistant strains of Mycobacterium tuberculosis. As part of our effort to...

Resource Type:

Article
Development of Novel Agents to Combat Tuberculosis and Malaria

Creator:

Almabruk, Khaled Husain G.

Abstract:

Despite the advance of biomedical science, infectious diseases remain one of the number one killers in the world. They claim the lives of millions of people annually, particularly in underdeveloped and developing countries. In fact, more than 32% of the health burden in Africa is caused by infectious diseases, e.g.,...

Resource Type:

Dissertation

Full Text:

, Anjali Saxena, Udita Mukherjee, Hardeep Kaur, Puneet Kohli, Rashmi Kumari, and Priya Singh did the