Search Constraints

Start Over
Filtering by: Subject Ketoconazole -- Mechanism of action Remove constraint Subject: Ketoconazole -- Mechanism of action Decade 2010-2019 Remove constraint Decade: 2010-2019

Search Results

  • Mechanistic Studies and Catalytic Engineering of the Pseudoglycosyltransferase VldE

    Creator:
    Abuelizz, Hatem A.
    Abstract:
    This thesis describes an investigation of the molecular basis of the substrate specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a newly discovered group of glycosyltransferase (GT)-like proteins that catalyze the transfer of a pseudosugar to an acceptor molecule via a C-N bond formation. This...
    Resource Type:
    Dissertation
    Full Text:
    specificity and catalytic mechanism of a unique pseudoglycosyltransferase (PsGT) enzyme, VldE. PsGTs are a