Index Catalog // ScholarsArchive@OSU

Creator:: Hall, Andrea Renée
Abstract:: Peroxiredoxins (Prxs) are dominant peroxide-reducing enzymes with two important roles: they protect all organisms from oxidative damage induced by peroxides, and in eukaryotes, they participate in hydrogen peroxide signaling pathways. This dissertation presents studies aimed at the biophysical characterization of select Prxs and a Prx reductase to elucidate their structure-function...
Resource Type:: Dissertation
Full Text:: and hemoglobin, awarded to J. C. Kendrew, M. Perutz), there have been 16 Nobel Prizes in chemistry

Creator:: Moriarty, Nigel W., Tronrud, Dale E., Adams, Paul D., and Karplus, P. Andrew
Abstract:: Ideal values of bond angles and lengths used as external restraints are crucial for the successful refinement of protein crystal structures at all but the highest of resolutions. The restraints in common usage today have been designed based on the assumption that each type of bond or angle has a...
Resource Type:: Article
Full Text:: References 1 Watenpaugh K, Sieker L, Herriott J & Jensen L (1973) Refinement of the model of a protein

Creator:: Caley, Jeffrey A.
Abstract:: Emerging applications for robotic data collection include ocean monitoring, emergency response and urban search and rescue. At the core of these applications is a robot's ability to make informed decisions on incomplete data. This dissertation addresses this problem by developing novel techniques for modeling and estimating structured environments using deep...
Resource Type:: Dissertation
Full Text:: this case, the robot does not update any new cells in the occupancy grid. d,e,f,g,h,i,j) The robot

Creator:: Raghavan, Aswin
Abstract:: Markov Decision Processes (MDPs) are the de-facto formalism for studying sequential decision making problems with uncertainty, ranging from classical problems such as inventory control and path planning, to more complex problems such as reservoir control under rainfall uncertainty and emergency response optimization for fire and medical emergencies. Most prior research...
Resource Type:: Dissertation
Full Text:: Improvement (V 0n+1, π)← T (Vn) if ||V 0n+1 − Vn|| ≤ �(1− γ)/2γ return (Vn, π) //Partial Policy Evaluation j

Creator:: Berry, Michael D.
Abstract:: This dissertation presents an analysis of transportable biomass conversion facility design to evaluate the conceptual and economic viability of a mobile and modular biomass conversion supply chain in the Pacific Northwest, USA. The main goal of this work is to develop a decision support system to more effectively and sustainably...
Resource Type:: Dissertation
Full Text:: ................................................................211 Appendix J - Glossary

Creator:: Brereton, Andrew E.
Abstract:: Life on Earth intimately depends on the function of countless proteins. For the majority of studied proteins, function absolutely depends on conformation (i.e. 3-dimensional shape in solution). The exact nature of how a protein goes from an unfolded linear polypeptide chain to an organized folded molecule is still not known,...
Resource Type:: Dissertation

Creator:: Mokhtari, Zahra
Abstract:: In a relay network for full truckload (TL) transportation, facilities known as relay points (RPs) serve as exchange points where truck drivers can exchange trailers. This would help carriers to assign more regular tours to drivers when compared to the excessively long tours that exist in the traditional Point-to-Point (PtP)...
Resource Type:: Dissertation
Full Text:: where a load is transported from node i to node j using three RPs. Figure 1: Example of a

Creator:: Adams, Paul D., Aertgeerts, Kathleen, Bauer, Cary, Bell, Jeffrey A., Berman, Helen M., Bhat, Talapady N., Blaney, Jeff M., Bolton, Evan, Bricogne, Gerard, Brown, David, Burley, Stephen K., Case, David A., Clark, Kirk L., Darden, Tom, Emsley, Paul, Feher, Victoria A., Feng, Zukang, Groom, Colin R., Harris, Seth F., Hendle, Jorg, Holder, Thomas, Joachimiak, Andrzej, Kleywegt, Gerard J., Krojer, Tobias, Marcotrigiano, Joseph, Mark, Alan E., Markley, John L., Miller, Matthew, Minor, Wladek, Montelione, Gaetano T., Murshudov, Garib, Nakagawa, Atsushi, Nakamura, Haruki, Nicholls, Anthony, Nicklaus, Marc, Nolte, Robert T., Padyana, Anil K., Peishoff, Catherine E., Pieniazek, Susan, Read, Randy J., Shao, Chenghua, Sheriff, Steven, Smart, Oliver, Soisson, Stephen, Spurlino, John, Stouch, Terry, Svobodova, Radka, Tempel, Wolfram, Terwilliger, Thomas C., Tronrud, Dale, Velankar, Sameer, Ward, Suzanna C., Warren, Gregory L., Westbrook, John D., Williams, Pamela, Yang, Huanwang, and Young, Jasmine
Abstract:: Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
Resource Type:: Article

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