Index Catalog // ScholarsArchive@OSU

Inhibitory Effect of Paclitaxel and Rapamycin Individual and Dual Drug-Loaded Polymeric Micelles in the Angiogenic Cascade

Creator:: Mishra, Gyan P., Nguyen, Duc, and Alani, Adam W. G.
Abstract:: Angiogenesis is an essential process for disease progression in many solid tumors. There are several major cascade events in the angiogenic process that can be targeted to inhibit new blood vessel formation in the tumor tissue. The purpose of this work is to evaluate the inhibitory effect of paclitaxel (PTX)...
Resource Type:: Article
Full Text:: Mishra, G. P., Nguyen, D., & Alani, A. W. G. (2013). Inhibitory effect of paclitaxel and rapamycin

Antiangiogenic Effect of Docetaxel and Everolimus as Individual and Dual-Drug-Loaded Micellar Nanocarriers

Creator:: Mishra, Gyan P., Doddapaneni, Bhuvana Shyam, Nguyen, Duc, and Alani, Adam W. G.
Abstract:: PURPOSE: The in vitro inhibitory effect of Docetaxel (DTX) and Everolimus (EVR) alone and together in poly(ethylene glycol)-block-poly(D,L-lactic acid) (PEG-b-PLA) nanocarriers on angiogenic processes and acute toxicity in mice was evaluated. METHODS: PEG-b-PLA DTX and/or EVR nanocarriers were characterized for size, drug loading, stability, and drug release. Cell proliferation, tubule...
Resource Type:: Article
Full Text:: Everolimus as individual and dual-drug loaded micellar nanocarriers Gyan P. Mishra, Bhuvana Shyam

In Situ Gelling Polyvalerolactone-Based Thermosensitive Hydrogel for Sustained Drug Delivery

Creator:: Mishra, Gyan P., Kinser, Reid, Wierzbicki, Igor H., Alany, Raid G., and Alani, Adam W. G.
Abstract:: Biodegradable poly(ethyleneglycol)-poly(valerolactone)-poly(ethyleneglycol) [PEG-PVL-PEG] copolymers were synthesized through ring opening polymerization of δ-valerolactone (VL) followed by the coupling of monomethoxy poly(ethyleneglycol-poly(valerolactone) (mPEG-PVL) with hexamethylene diisocyanate (HDI). The copolymers were characterized by ¹H NMR, FT-IR, and GPC. Block copolymers of PEG and PVL with different VL/PEG molar ratios were successfully synthesized. One...
Resource Type:: Article
Full Text:: Hydrogel for Sustained Drug Delivery Mishra, G. P., Kinser, R., Wierzbicki, I. H., Alany, R. G., & Alani

Comparison of process stability in methane generation from palm oil mill effluent using dairy manure as inoculum

Creator:: Krishnan, Santhana, Singh, Lakhveer, Mishra, Puranjan, Nasrullah, Mohd, Sakinah, Mimi, Thakur, Sveta, Siddique, Nurul Islam, and Ab Wahid, Zularisam
Abstract:: The potential of methane production in a continuously stirred tank reactor (CSTR) was investigated using dairy manure as inoculum at pH 6.8 and 37 degrees C temperature in this study. Two identical anaerobic bioreactors namely CSTR1 and CSTR2 filled with palm oil mill effluent (POME) as a carbon source were...
Resource Type:: Article
Full Text:: using dairy manure as inoculum Santhana Krishnan a, Lakhveer Singh b, Puranjan Mishra a, Mohd Nasrullah

Photohydrogen production from dark-fermented palm oil mill effluent (DPOME) and statistical optimization: Renewable substrate for hydrogen

Creator:: Mishra, Puranjan, Singh, Lakhveer, Ab Wahid, Zularisam, Krishnan, Santhana, Rana, Supriyanka, Islam, M. Amirul, Sakinah, Mimi, Ameen, Fuad, and Syed, A.
Abstract:: Biological hydrogen production through photo-fermentative process using dark fermented palm oil effluent (DPOME) is a cost effective and environmentally benign process. In this study, effect of various factors like light intensity, agitation rate and dilution of DPOME on the hydrogen productivity of Rhodopseudomanas palustris were investigated using batch system. Investigation...
Resource Type:: Article
Full Text:: : Renewable substrate for hydrogen Puranjan Mishra a, Lakhveer Singh a, b, Zularisam Ab Wahid a, *, Santhana

Is platelet rich plasma (PRP) the other alternative? A review and current research

Creator:: Ho, Louisa K. K.
Abstract:: Platelet-rich plasma (PRP) has been applied as a hemostatic agent since the 1970s, and a potent source of autologous growth factors since the 1990s. PRP is rich in growth factors such as platelet derived growth factor (PDGF), vascular endothelial growth factor (VEGF), transforming growth factor-β (TGF-β), fibroblast growth factor (FGF)...
Resource Type:: Masters Thesis
Full Text:: cells) classification system by DeLong et al, 22 and a sports medicine system by Mishra et al. 33

Development of thermosensitive injectable hydrogel and transdermal controlled release formulations for Tacrolimus

Creator:: Nguyen, Duc X.
Abstract:: TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...
Resource Type:: Dissertation
Full Text:: . Adam Alani and Duc Nguyen designed majority of the experiments. Dr. Gyan Mishra provided technical

A motor-generator and supercapacitor based system for microgrid frequency stabilization

Creator:: Crispo, Richard F.
Abstract:: This research introduces an energy storage system to deliver microgrid frequency response. A doubly-fed induction generator (DFIG) and a squirrel cage induction machine (SCIM) are coupled together as a motor/generator set to deliver an immediate inertial response to a change of frequency, and an inverter and supercapacitors deliver short term...
Resource Type:: Masters Thesis
Full Text:: stabilize the system frequency under various load/source conditions. Mishra et. al [12] simulate a

Linearizing techniques for voltage controlled oscillator based analog to digital converters

Creator:: Rao, Sachin B.
Abstract:: Voltage controlled oscillator (VCO) based ADC is an important class of time-domain ADC that has gained widespread acceptance due to their several desirable properties. VCO-based ADCs behave like an open-loop continuous time ΔΣ modulator and achieve excellent resolution by first order noise shaping the quantization error. However, the SNDR of...
Resource Type:: Dissertation
Full Text:: ) K which indicates that the problem is especially severe at low OSR. For example, from Eq. 3.6

Phylogeography and Evolution of Effector Genes in Phytophthora Species

Creator:: Shakya, Shankar K.
Abstract:: Plant pathogens in the genus Phytophthora are known to cause disease on field crops, nursery plants, and forest trees. The best known example probably is Phytophthora infestans, which triggered the infamous Irish potato famine. Other important Phytophthora species include: P. ramorum (sudden oak death pathogen), P. sojae (soybean root rot...
Resource Type:: Dissertation
Full Text:: . CONTRIBUTION OF AUTHORS Chapter 2 Shankar K. Shakya, Héctor Lozoya-Saldaña and Niklaus Grünwald

ScholarsArchive@OSU

Inhibitory Effect of Paclitaxel and Rapamycin Individual and Dual Drug-Loaded Polymeric Micelles in the Angiogenic Cascade

Antiangiogenic Effect of Docetaxel and Everolimus as Individual and Dual-Drug-Loaded Micellar Nanocarriers

In Situ Gelling Polyvalerolactone-Based Thermosensitive Hydrogel for Sustained Drug Delivery

Comparison of process stability in methane generation from palm oil mill effluent using dairy manure as inoculum

Photohydrogen production from dark-fermented palm oil mill effluent (DPOME) and statistical optimization: Renewable substrate for hydrogen

Is platelet rich plasma (PRP) the other alternative? A review and current research

Development of thermosensitive injectable hydrogel and transdermal controlled release formulations for Tacrolimus

A motor-generator and supercapacitor based system for microgrid frequency stabilization

Linearizing techniques for voltage controlled oscillator based analog to digital converters

Phylogeography and Evolution of Effector Genes in Phytophthora Species

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Conference Name

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Location

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search