Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (B[a]P), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (αT) supplementation decreases B[a]P-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that αT protection from B[a]P exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
Cisplatin (CDDP) is a highly active platinum-containing chemotherapeutic agent for use against solid tumors, including ovarian. However, like most antitumor agents, CDDP use is accompanied by non-tumor tissue toxicities leading to unwanted side effects, including neuropathy. To date, the mechanism(s) for these side effects are undefined. However, the clinical features...
Polycyclic aromatic hydrocarbons (PAHs), including benzo[a]pyrene (BP), are environmental pollutants linked to increased disease susceptibilities. Alpha-Tocopherol (aT) supplementation decreases BP-DNA adducts in smokers, particularly women; but the mechanism is unknown. To test the hypothesis that aT protection from BP exposure is gender-dependent, male and female rats received 7 daily subcutaneous...
Background: Lateral gene transfer (LGT) among C. trachomatis strains is common, both in isolates generated in the laboratory and those examined directly from patients. This is a challenging concept because there are very few examples of recent acquisition of foreign DNA by Chlamydia spp. There is no understanding of the...
Large population sizes and global distributions generally associate with high mitochondrial DNA control region (CR) diversity. The sperm whale (Physeter macrocephalus) is an exception, showing low CR diversity relative to other cetaceans; however, diversity levels throughout the remainder of the sperm whale mitogenome are unknown. We sequenced 20 mitogenomes from...
In 2014, Oregon State University (OSU) initiated a multi-year project to study humpback whale (Megaptera novaeangliae) migrations in the North Pacific Ocean using satellite tracking technology in combination with genetic and photo-identification (photo-ID) analyses. The study is highly relevant to management, given the need for new information arising from the...
We present genetic and morphological evidence supporting the recognition of a previously synonymized species of Mesoplodon beaked whale in the tropical Indo-Pacific, Mesoplodon hotaula. Although the new species is closely-related to the rare ginkgo-toothed beaked whale M. ginkgodens, we show that these two lineages can be differentiated by maternally (mitochondrial...
We quantified the relative influence of maternal fidelity to feeding grounds and natal
fidelity to breeding grounds on the population structure of humpback whales Megaptera novae-angliae based on an ocean-wide survey of mitochondrial (mt) DNA diversity in the North Pacific.
For 2193 biopsy samples collected from whales in 10 feeding...
The purpose of this dissertation was to contribute to deeper understanding of how client’s experience their spirituality and religion during the therapy process. The first manuscript is located in chapter 2 and titled A Qualitative Metasynthesis of Client Experience of Addressing Spirituality and Religion in Counseling. This metasynthesis pools together...
The rapid decline of marine ecosystems worldwide and the failure of traditional single species management pushed for the development of ecosystem-based conservation measures such as marine protected areas (MPA) to slow the loss of marine biodiversity. One approach to MPA creation advocates targeting marine megafauna (e.g., marine mammals, seabirds, sharks,...