During the eighteenth century, diagrams increasingly became an important aspect of scientific inquiry. Diagrams employed simplification as a strategy for representing complex information, played a role in standardizing scientific language, and served as instruments of reason to think through and communicate problems and findings in mathematics, physics, chemistry, astronomy, natural...
3D volume segmentation is a fundamental process in many scientific and medical applications. Producing accurate segmentations, in an efficient way, is challenging, in part due to low imaging data quality (e.g., noise and low image resolution), and ambiguity in the data that can only be resolved with higher-level knowledge of...
My work has focused on investigating synthetic organic reactions using applied computational methods. Non-covalent interactions are critical to catalysis, mechanism, and stereoselectivity, with the most prominent interaction for isothioureas being the S···O contact between the catalyst sulfur atom and the oxygen of the acyl group. A comprehensive joint experimental and...
Commercial fishing is a culturally and economically significant industry on the Oregon coast. The importance of this industry to human communities is often neglected in fisheries research, with economic and ecological data being favored by managers and decision makers. Recent observations in many coastal communities have indicated aging of fishermen...
Following a history of tensions surrounding concubinage in medieval and early modern Spain, the Church sought greater control of religious life, particularly over the sacrament of marriage, via the Holy Office of the Inquisition. The Church exercised its strengthened restrictions and prosecuted these relationships with more frequency, as did civil...
The Pacific Northwest (Oregon and Washington in the United States and British Columbia in Canada) is one of the major producers of red raspberry (Rubus idaeus L.) and blueberry (Vaccinium corymbosum L.) in the world. The expansion of growing area with these crops has resulted in the emergence of new...
Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Viruses and other selfish genetic elements are dominant entities in the biosphere, with respect to both physical abundance and genetic diversity. Various selfish elements parasitize on all cellular life forms. The relative abundances of different classes of viruses are dramatically different between prokaryotes and eukaryotes. In prokaryotes, the great majority...
Blackberry (Rubus sp.) fruit are a good source of phenolic compounds and anthocyanins, and are consumed in fresh and processed forms. Though organic products become more popular, limited information is available about how different organic production methods affect the post-harvest quality of blackberry fruit. The objective of this project was...
In real networks, identifying dense regions is of great importance. For example, in a network that represents academic collaboration, authors within the densest component of the graph tend to be the most prolific. Dense subgraphs often identify communities in social networks. And dense subgraphs can be used to discover regulatory...