Heavy alcohol consumption reduces peak bone mass in growing rodents and can lead to bone loss in both adult rats and humans. In contrast, moderate alcohol consumption appears to have a bone sparing effect in post-menopausal women. Alcohol has been reported to increase aromatase activity and influence estrogen receptor (ER)...
The present studies investigated the cellular mechanisms for the detrimental effects of high dose whole body γ-irradiation on bone. In addition, radioadaptation and bone marrow transplantation were assessed as interventions to mitigate the skeletal complications of irradiation. Increased trabecular thickness and separation and reduced cancellous bone volume fraction, connectivity density,...
It is good practice to fully understand components of an ecosystem if we hope to preserve its biodiversity. A problem is that we know very little about some organisms and nothing of others. Studies that investigate an organism’s basic biological, ecological and physiological life history variables advance our knowledge of...
In this dissertation, the spectroscopic properties and thermodynamic stability of a class of materials known as metal oxo and hydroxo clusters are studied. In aqueous solutions, many metals can aggregate into discrete clusters of metals bridged by oxo or hydroxo ligands. These clusters are of particular interest to us for...
Oregon is one of several states to implement a new and innovative minimum wage policy. The Oregon policy defines three regions with each having a separate initial minimum wage and a different set of incremental increases over the next seven years. This paper explores how this policy change may impact...
Flaxseed is a rich source of alpha-linolenic acid (ALA). Feeding laying hens flax seed can increase n-3 fatty acids content (FA) in eggs, thus increasing human intake of n-3 FA. However, non-starch polysaccharides (NSP), which decreases digestibility of dietary lipids and proteins. Addition of carbohydrase enzymes to flax-based layer diets...
BACKGROUND: Meniscal injury is a common cause of lameness in the dog. Tissue engineered bioscaffolds may be a treatment option for meniscal incompetency, and ideally would possess meniscus-like extracellular matrix (ECM) and withstand meniscal tensile hoop strains. Synovium may be a useful cell source for meniscal tissue engineering because of...
We compiled a lake-water clarity database using publically available, citizen volunteer observations made between 1938 and 2012 across eight states in the Upper Midwest, USA. Our objectives were to determine (1) whether temporal trends in lake-water clarity existed across this large geographic area and (2) whether trends were related to...
Objective. To determine the utility of the capacity ratio to measure and compare solvency in experiential
education in 6 colleges and schools of pharmacy in the Northwestern United States.
Methods. The 6 colleges and schools of pharmacy combined data on student placements needed, site
availability, and changes made to placements...
Mantel-based tests have been the primary analytical methods for understanding how landscape features influence observed spatial genetic structure. Simulation studies examining Mantel-based approaches have highlighted major challenges associated with the use of such tests and fueled debate on when the Mantel test is appropriate for landscape genetics studies. We aim...