Index Catalog // ScholarsArchive@OSU

Beating the curve: insulin sensitization in response to exercise

Creator:: Murphy, Michael C.
Abstract:: This paper presents a brief discussion on the phenomenon of exercise-induced insulin sensitization, including the effects of exercise on insulin-stimulated glucose uptake and potential mechanisms mediating these effects. Originally created for KIN 481 (Writing Intensive Curriculum course).
Resource Type:: Research Paper
Full Text:: . https://doi.org/10.1172/JCI111938 DeFronzo, R. A., Jacot, E., Jequier, E., Maeder, E., Wahren, J

The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections

Creator:: Hickman, Mark R., Saunders, David L., Bigger, Catherine A., Kane, Christopher D., and Iversen, Patrick L.
Abstract:: The Joint Program Executive Office for Chemical, Biological, Radiological, and Nuclear Defense (JPEO-CBRND) began development of a broad-spectrum antiviral countermeasure against deliberate use of high-consequence viral hemorrhagic fevers (VHFs) in 2016. The effort featured comprehensive preclinical research, including laboratory testing and rapid advancement of lead molecules into nonhuman primate (NHP)...
Resource Type:: Article

Regulation of Skeletal Muscle Insulin Action and Fatty Acid Trafficking with Obesity and Exercise

Creator:: Stierwalt, Harrison D.
Abstract:: Altered skeletal muscle fat metabolism is linked to changes in skeletal muscle insulin sensitivity. Whereby the accumulation of bioactive signaling lipids (i.e., diacylglycerols and ceramides) within skeletal muscle are negatively associated with insulin sensitivity and the exercise-induced changes to fatty acid trafficking are related to improved skeletal muscle insulin action....
Resource Type:: Dissertation

The effect of feeding spent hemp biomass on bone growth in broiler chickens

Creator:: Pearce, Carolyn
Abstract:: Spent hemp biomass (SHB) is a byproduct of the cannabinoid oil production which currently is not approved as a livestock feed ingredient. The 2018 Farm Bill defined the difference between varieties of the cannabis sativa plant as either non-hemp cannabis or hemp which has equal to or less than 0.3...
Resource Type:: Honors College Thesis
Full Text:: hematopoietic stem/progenitor cell trafficking. J. Clin. Invest. 129:2920–2931. doi:10.1172/JCI124829.

Evaluation of a Monoclonal Antibody for Studying MHC Class I Antigen Presentation In-Vitro

Creator:: VanderHoek, Eden N.
Abstract:: Human epidermal growth factor receptor 2 (HER2), a member of the receptor tyrosine kinase (RTK) family, is frequently dysregulated in a variety of cancers. Overexpression of the receptor leads to increased cell proliferation and resistance to cell death due to downstream signaling effects. Proteasomal degradation of HER2 results in the...
Resource Type:: Honors College Thesis
Full Text:: . 2015, pp. 3335–37. PubMed Central, doi:10.1172/JCI83871.

Self-Advocacy for Female Patients with Chronic Pain

Creator:: Smith, McGwire
Abstract:: A significant proportion of the population of the United States suffers from chronic pain, a category of disease that is not yet well understood by healthcare professionals. A majority of this group is made up of women; individuals who often have to convince healthcare professionals that their symptoms are real...
Resource Type:: Honors College Thesis
Full Text:: :10.1172/jci45178. Wright, Danyeal M., et al. “Activation of Membrane Estrogen Receptors Attenuates NOP

Role of MEK Mutations in Trametinib Resistant Acute Myeloid Leukemia Cells

Creator:: Beer, Sofia R.
Abstract:: Acute myeloid leukemia (AML) is a blood malignancy characterized by a differentiation and proliferation defect of myeloid progenitors leading to accumulation of myeloid blasts. It is one of the most common leukemias in adults. Trametinib (Mekinist) is a small molecule inhibitor that targets MEK1 (MAP2K1) and MEK2 (MAPK2K2). It has...
Resource Type:: Honors College Thesis
Full Text:: investigation, 108(6), 851– 859. doi:10.1172/JCI12807 7. Leukemia. (2019). Retrieved June 21, 2019, from

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation

Investigation of the Patterns and Transcriptional Regulators from Gene Expression Profiles of Adult Murine Soleus and Tibialis Anterior Skeletal Muscles

Creator:: Alto, Sarah I.
Abstract:: Skeletal muscles provide several functions, including, yet not limited to, voluntary body movement and locomotion, posture and body position, and soft tissue support. Skeletal muscles also play a role in metabolism, requiring energy to facilitate contraction. Each skeletal muscle serves a different purpose despite seeming to perform the same task....
Resource Type:: Dissertation

State-of-the-Art Combination Therapies and Nanomedicines for Triple Negative Breast Cancer

Creator:: Fabbi, Meagan C.
Abstract:: Triple-negative breast cancer (TNBC) is a particularly aggressive molecular subtype of malignant cells that tends to proliferate quickly and is commonly resistant to traditional chemotherapy leading to relapses in prognosis more frequently than other forms of breast cancer (BCa) [1][2][3]. Current treatment options include surgical resection of cancerous tissue and...
Resource Type:: Honors College Thesis

ScholarsArchive@OSU

Beating the curve: insulin sensitization in response to exercise

The development of broad-spectrum antiviral medical countermeasures to treat viral hemorrhagic fevers caused by natural or weaponized virus infections

Regulation of Skeletal Muscle Insulin Action and Fatty Acid Trafficking with Obesity and Exercise

The effect of feeding spent hemp biomass on bone growth in broiler chickens

Evaluation of a Monoclonal Antibody for Studying MHC Class I Antigen Presentation In-Vitro

Self-Advocacy for Female Patients with Chronic Pain

Role of MEK Mutations in Trametinib Resistant Acute Myeloid Leukemia Cells

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Investigation of the Patterns and Transcriptional Regulators from Gene Expression Profiles of Adult Murine Soleus and Tibialis Anterior Skeletal Muscles

State-of-the-Art Combination Therapies and Nanomedicines for Triple Negative Breast Cancer

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Location

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search