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Filtering by: Committee Member Spinrad, B. I. Decade 2020-2029

Regulation of Skeletal Muscle Mitophagy in Response to High-fat Feeding and Exercise Training

Creator:

Ehrlicher, Sarah E.

Abstract:

Understanding the mechanisms regulating mitochondrial respiratory function and adaptations to metabolic challenges, such as exercise and high dietary fat, is necessary to promote skeletal muscle health and attenuate metabolic disease. Autophagy is a constitutively active degradation pathway that promotes mitochondrial turnover and is suppressed by insulin and activated by exercise....

Resource Type:

Dissertation

Full Text:

Biological and Population Health Sciences Dean of the Graduate School I
Exploring the Limits of Ligation Rate and Specificity in Protein Immobilization Using the Genetically Encoded Tetrazine Ligation

Creator:

Bednar, Riley M.

Abstract:

Immobilized proteins are integral components of a number of important technologies, including the principal component of many biosensors, as functional coatings in various implants, as catalysts is industrial biosynthesis, and as the building blocks of next-generation nanotechnologies. Despite their ubiquity, relatively little is known about the processes that shape immobilized...

Resource Type:

Dissertation

Full Text:

Program Dean of the Graduate School I understand that my