Index Catalog // ScholarsArchive@OSU

Comparative Aquatic Toxicology of Pesticides and Plastics Using the Model Estuarine Fish, Inland Silverside

Creator:: Hutton, Sara J.
Abstract:: Based on current trends both pesticide and plastic production are expected to continue to rise in the coming decade. A growing global population coupled with the effects of climate change are the main drivers of increased pesticide use. Throughout this dissertation pesticides refer to herbicides, fungicides, and insecticides. Plastic production...
Resource Type:: Dissertation
Full Text:: OF THE DISSERTATION OF Sara J. Hutton for the degree of Doctor of Philosophy in Toxicology

Per- and Polyfluoroalkyl Substances (PFAS): Protein Binding and Partitioning and Sorption in Light Non-Aqueous Phase Liquids

Creator:: Christie, Emerson C.
Abstract:: Per- and polyfluoroalkyl substances (PFAS) are anthropogenic surfactants that have recently been identified as persistent organic pollutants. These so called “Forever Chemicals” have been detected in drinking waters, ground waters, soils, and consumer and industrial products globally; with environmental impacts stretching into the artic, far from known PFAS sources. The...
Resource Type:: Dissertation
Full Text:: . Christie for the degree of Doctor of Philosophy in Toxicology presented on March 11, 2021. Title

Advanced Approaches in Hazard Assessment of Polycyclic Aromatic Hydrocarbons Using Zebrafish

Creator:: Wilson, Lindsay B.
Abstract:: The field of toxicology is challenged with a vast number of environmental chemicals and mixtures to which humans and ecosystems are exposed with limited toxicity data available. Chemical hazard assessment traditionally utilizes mammalian models and can be both cost- and time-limiting and may pose ethical concerns. To rapidly tackle this...
Resource Type:: Dissertation
Full Text:: Barbara Wilson for the degree of Doctor of Philosophy in Toxicology presented on January 13, 2023

Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

Creator:: Chang, Yvonne
Abstract:: The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
Resource Type:: Dissertation
Full Text:: degree of Doctor of Philosophy in Toxicology presented on June 11, 2020. Title: Toxicogenomic

Assessing the toxicity of nanoplastics using the primary human bronchial epithelial model

Creator:: Germano, Francesca
Abstract:: Emerging data showing the presence of atmospheric microplastics (MPs) has recently raised awareness surrounding the potential of human nanoplastics (NPs) exposure. Due to factors such as weathering, UV exposure, and other biodegradation processes, plastic pollution in the environment breaks down over time into micro (<5 micrometers) and nanoscale (<1000nm) particles....
Resource Type:: Masters Thesis
Full Text:: Germano for the degree of Masters of Science in Toxicology presented on June 6, 2023. Title

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Creator:: Lopez, Ryan
Abstract:: Graphene and its derivatives are two-dimensional hexagonal lattices that possess desirable physicochemical properties leading to an ever-expanding list of industrial and biomedical uses. Graphene oxides (GOs) are becoming a popular graphene alternative and while there have been human safety studies, investigations of developmental toxicity are lacking. The use of distinct...
Resource Type:: Masters Thesis
Full Text:: Ryan Lopez for the degree of Master of Science in Toxicology presented on November 2, 2021. Title

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

Creator:: Schaum, Andre F.
Abstract:: Aqueous film-forming foams (AFFFs) are significant sources of per- and polyfluoroalkyl substances (PFAS) in the environment. Current analytical methods that provide quantitative measures of individual PFAS in AFFFs, such as liquid chromatography – tandem mass spectrometry (LC-MS/MS), are often complicated, time-consuming, and expensive. Methods for total fluorine analysis, though quantitative,...
Resource Type:: Masters Thesis
Full Text:: . Schaum for the degree of Master of Science in Toxicology presented on May 25, 2022. Title

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Creator:: Rivera, Brianna N.
Abstract:: Throughout their lifetime individuals are exposed to complex mixtures of chemicals. The study of chemical mixtures is an internationally recognized research priority, but seemingly complex challenge. To reduce the intricacy of studying mixtures, researchers have identified different prioritization methods based on exposure or the toxicity of chemicals. However, understanding the...
Resource Type:: Dissertation
Full Text:: Brianna N. Rivera for the degree of Doctor of Philosophy in Toxicology presented on June 10, 2022

Exploring Silicone Wristbands as Personal Passive Sampling Devices in a Disaster Scenario

Creator:: Samon, Samantha M.
Abstract:: Exposure assessment is necessary to determine the frequency and magnitude of environmental contaminants, especially since exposure may lead to adverse health outcomes. Traditional personal exposure assessment tools such as biological samples are limited in their ability to capture a wide range of chemical exposures from a single sample, and others...
Resource Type:: Dissertation
Full Text:: DISSERTATION OF Samantha M. Samon for the degree of Doctor of Philosophy in Toxicology presented on April

Implications for Wildfire Health Recommendations and Remediation Strategies: Source, Fate and Risk of PAHs

Creator:: Ghetu, Christine, C.
Abstract:: (Polycyclic aromatic hydrocarbons) PAHs are widespread in the environment, and are derived from both natural and anthropogenic sources. The physicochemical properties of PAHs along with the wide range of PAH sources leads to their persistence in the environment. Since PAHs are ubiquitous, and have the potential to illicit adverse effects,...
Resource Type:: Dissertation
Full Text:: . Ghetu for the degree of Doctor of Philosophy in Toxicology presented on September 30, 2021. Title

ScholarsArchive@OSU

Comparative Aquatic Toxicology of Pesticides and Plastics Using the Model Estuarine Fish, Inland Silverside

Per- and Polyfluoroalkyl Substances (PFAS): Protein Binding and Partitioning and Sorption in Light Non-Aqueous Phase Liquids

Advanced Approaches in Hazard Assessment of Polycyclic Aromatic Hydrocarbons Using Zebrafish

Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

Assessing the toxicity of nanoplastics using the primary human bronchial epithelial model

Size- and Oxidation-Dependent Toxicity of Graphene Oxide Nanomaterials in Embryonic Zebrafish

Expanding the Use of 19F NMR Spectroscopy in Per- and Polyfluoroalkyl Substance Analysis: Determination of Total Fluorine and Isomeric Distribution in Aqueous Film-Forming Foams

Assessing Exposures and Simplifying Complex Mixtures of SVOCs for Hazard Characterization using Alternative Model Systems

Exploring Silicone Wristbands as Personal Passive Sampling Devices in a Disaster Scenario

Implications for Wildfire Health Recommendations and Remediation Strategies: Source, Fate and Risk of PAHs

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