Intracellular delivery of mRNA holds great potential for vaccine and therapeutic discovery and development. This is realized by the preeminent role mRNA is playing in the record-breaking pace of SARS-CoV-19 vaccine development. Recent advances in chemical modifications of mRNA have enabled high-efficiency gene expression with superior spatiotemporal control while eliminating...
In recent years, the research community's interest in fully integrated mm-Wave wireless communication systems has increased significantly. With the standards for 5G NR now in place, the focus has shifted to actual deployment. Mm-Wave systems provide wider bandwidths, higher capacity, and lower latency than existing systems such as 4G. Higher...
Humanitarian logistics in the post-disaster phase of an earthquake requires detailed planning about the relief distribution network including assigning available distribution centers (DCs) to the affected areas, distribution of the relief commodities demanded by the affected population, and efficient allocation of the available vehicle fleet for the distribution in a...
The Machine Learning (ML) algorithms are increasingly explored in varies of fields including designing and optimizing computer systems. Recent research, such as optimizing memory/cache prefetching by ML training or predicting traffic pattern in throughput processors, also exhibits a promising future of introducing ML into computer system design and optimization. Throughput...
Spectrum overcrowding, ever increasing demand for high data rate and increased mobility requirements are three major challenges 5G-technology is trying to address. In this thesis I start with a RF front-end technique that deals with blocker interference arising from spectrum overcrowding both across frequency bands and within the same frequency...