Real world is analog but the processing of signals can best be done in digital domain. So the need for Analog to Digital Converters(ADCs) is ever rising as more and more applications set in. With the advent of mobile technology, power in electronic equipment is being driven down to get...
Dynamic CMOS circuits are commonly used in high-performance memory arrays to implement wide-NOR logic functions for their read and search operations. This is because dynamic circuits have significantly higher speed and lower area compared to static circuits for performing similar operations. Register File (RF) arrays are located at the top...
New highly polymorphic simple sequence repeat (SSR) markers for European hazelnut (Corylus avellana L.). were developed from several sources. The markers were characterized, and segregation in a mapping population allowed to assign them to linkage groups. Their transferability across genera and species in the Betulaceae family was investigated. SSR markers...
Ever since composite laminate technology was introduced into the aerospace and automotive industry, there has been a need to fully understand the damage progression experienced by composite laminated plates in the presence of a notch. While numerous research studies have been conducted on this matter when subjected to in-plane loads,...
In this dissertation, we present a user-in-the-loop method for the design of an interactive motion data structure that benefits from the advantages of both motion graphs and blend-based techniques. Our novel approach automatically analyzes a traditional motion graph built from labeled motion clips. The result is a more condensed, coarser...
The concept of reducing laboratory operations in scale such that they fit on a microfluidic chip has been met with great enthusiasm. Lab-on-a-chip devices promise to be cost effective to operate due to reduced reagent consumption, have the potential to offer shorter analysis times due to their short path lengths,...
The Change in Alcohol Consumption of Important People to Clients measures the relationship between outcomes of clients’ alcohol treatment and the changes in alcohol consumption by important people (IP) in clients’ social networks. The prevalence of alcoholism in America continues to negatively impact individuals and society, yet few people with...
Polycyclic aromatic hydrocarbons (PAHs) are a re-emerging class of environmental pollutants. The persistent nature of these highly toxic compounds along with their ubiquity in the environment creates an unavoidable route of exposure. The developing fetus and neonate are a particularly susceptible population due to their incomplete complement of xenobiotic metabolizing...
Papain-like leader proteases are found in diverse families of human, animal, plant, and fungal positive-strand RNA viruses. In addition to autocatalytic processing, these proteases play a variety of roles in the virus life cycle. In particular, the leader protease (L-Pro) of a prototype member of the Closterovirus genus, Beet yellows...
The purpose of this research was to develop tools and germplasm for the production of tomatoes (Solanum lycopersicum L.) with high fruit phenolics without the use of genetic engineering. A candidate gene analysis was undertaken to identify genes regulating anthocyanin biosynthesis in tomato fruit (Aft, Abg, atv, and Purple Smudge)....
In this dissertation I study evolutionary patterns at genes encoding antimicrobial peptides (AMPs) in frogs. AMPs are short, amphipathic, cationic, secreted proteins that kill bacteria and other pathogens through a non-catalytic mechanism that involves
binding to and disrupting the microbial cell membrane. In many animal taxa, positive selection is much...
School attendance is perceived as a critical issue in today’s primary and secondary educational systems. This manuscript reviews literature that speaks to the complexity of issues related to truancy and then posits that many of the interventions typically recommended to address truancy are ones that school counselors already provide or...
This research effort examined Traditional Ecological Knowledge (TEK) of Siletz tribal members of the environment they live and/or lived in, and how both Western societal beliefs and land reduction to the initially established reservation location affected and altered how the area TEK has been maintained and passed down. The theory...
Support Vector Machines (SVM) and Random Forests (RF) have
consistently outperformed other machine learning algorithms on a variety of
problems. SVM can be used for classification and regression on many types of
data (e.g. nonlinear, high dimensional), but cannot handle missing or mixed data.
This research implements a permutation-based variable...
Two forest management objectives being debated in the context of federally managed landscapes in the US Pacific Northwest involve a perceived trade-off between fire restoration and C sequestration. The former strategy would reduce fuel (and therefore C) that has accumulated through a century of fire suppression and exclusion that has...
Real-time, high efficiency neutron spectroscopy has, historically, been a persistent challenge in the field of radiation detection and, for the most part, has gone unsolved. The most promising method to resolve this challenge, is the boron-capture technique using an organic scintillation system (BC-523a). Detectors that utilize this method possess an...
Since the early 1990s, declines in northern spotted owl (Strix occidentalis caurina) populations have been documented through extensive field surveys and range-wide demographic analyses. Although loss of late-successional forest has been credited as the primary cause for spotted owl population declines, environmental variation has also been shown to influence vital...
Mycobacterium avium cause disseminated disease in immunocompromised people such as AIDS patients. Subsequent to crossing the intestinal epithelium, M. avium thrive within vacuoles in macrophages. The bacteria exhibit a different, more invasive, phenotype after being in macrophages compared to M. avium from laboratory conditions. We hypothesized that this intracellular phenotype...
The purpose of this case study was to examine a third-grade teacher’s effective use of mathematical discourse in the classroom setting. The study offers insights into the following research questions: 1) How does a teacher’s engagement in mathematical discourse communities influence her practice and self-efficacy as a mathematics educator? 2)...
In order to address the energy needs of developing countries and remote communities, Oregon State University has proposed the Multi-Application Small Light Water Reactor (MASLWR) design. In order to achieve five years of operation without refueling, use of 8% enriched fuel is necessary.
This dissertation is focused on core design...
Many conditions affecting hydrogen (H₂) production by the cyanobacterium, Synechocystis sp. PCC 6803, were optimized to yield maximum H₂ accumulation. Biological H₂ production from photosynthetic species is a promising form of renewable energy since an abundant supply of sunlight hits the Earth every day, and photosynthetic bacteria can harness this...
The purpose of this study was to investigate third year college students' transfer of learning of the concepts of eigenvalues and eigenvectors from the winter term physics courses to the interviews in which they participated before, during, and after these courses. Transfer of learning of each student was explored
by...
This thesis describes the chemical investigation of marine cyanobacteria collected in Madagascar and Panama with an emphasis on the isolation and structure elucidation of medicinally relevant secondary metabolites.
A collection of the marine cyanobacterium Lyngbya majuscula from the Radames Islands, Madagascar yielded two new cyclic depsipeptides, radamamides A and B,...
A striking feature in the study of Riemannian manifolds of positive sectional curvature
is the narrowness of the collection of known examples. In this thesis, we examine the
structure of the cohomology rings of three families of compact simply connected seven dimensional
Riemannian manifolds that may contain new examples of...
Automated recognition of object categories in images is a critical step for many real-world computer vision applications. Interest region detectors and region descriptors have been widely employed to tackle the variability of objects in pose, scale, lighting, texture, color, and so on. Different types of object recognition problems usually require...
This study investigated how a minority population of Latino/a immigrant children attending a middle school in the Pacific Northwest made sense of engaging with school and school mathematics. A cross disciplinary theoretical framework was used to examine how individual student motivation is impacted by the social context in which the...
Litter nutrient dynamics contribute significantly to biogeochemical cycling in
forest ecosystems. These dynamics may be influenced by site attributes, litter nutrient concentrations, and soil nutrient availability either independently or synergistically. Litter nutrient dynamics were examined in two decomposition studies in temperate coniferous forests of Oregon. I used ¹⁵N-labelled litter of...
One of the basic questions facing transportation planners and road managers is how to provide and maintain a road system that provides efficient access to the forest while limiting adverse effects roads can have on water and soil resources. The purpose of this study is to develop decision support models...
Knowledge workers are struggling in the information flood. There is a growing interest in intelligent desktop environments that help knowledge workers organize their daily life. Intelligent desktop environments allow the desktop user to define a set of “activities” that characterize the user’s desktop work. These environments then attempt to identify...
Evolution of the mobile communication standards and proliferation of hand-held devices mandate stringent Analog-to-Digital Converter (ADC) specifications. Among various ADCs, a ∆Σ ADC is best known as a power-efficient ADC when more than 12b is required. However, a conventional discrete-time (DT) ∆Σ Modulator (∆ΣM) is inadequate for low-power wideband applications...
The original research detailed in this document recognizes that the majority of students with disabilities between 18-69 years of age will attend a community college. The literature also indicates an exponential increase for better job opportunity and earnings relative to individuals with disabilities who attain higher levels of education. This...
Despite the advances in surgery, physical therapy, and pharmaceutical agents, muscle
dysfunction (i.e., atrophy and weakness) continues to impair recovery from an anterior
cruciate ligament (ACL) injury and surgery. Ischemia-reperfusion injury during surgery
and the subsequent limb disuse are two events experienced by patients having ACL
surgery. Oxidative stress and...
This dissertation has two objectives. The first objective is to determine where best to situate the study of mentoring (i.e. the 'making of scientists') on the landscape of the history of science and science studies. This task is accomplished by establishing mentoring studies as a link between the robust body...
Two-year chemistry-based technology training (CBTT) programs in the U.S. are important in the preparation of the professional technical workforce. The purpose of this study was to identify, examine, and analyze factors related to the economic sustainability of CBTT programs. A review of literature identified four clustered categories of 31 sub-factors...
The purpose of this study is to explore the factors that led to the move to include non-need aid in community college institutional financial aid policies. The following questions guided the research: (1) What meaning do those involved in the
formulation of institutional financial aid policy at community colleges give...
The purpose of this study is to examine the role of a Filipino American college student organization at a Predominantly White Institution, and uncover elements of the organization that influence or limit the development of critical consciousness of its members. This study focuses on the aspect of critical consciousness that...
Many conventionally reinforced concrete deck girder bridges (RCDG) and their intermediate supporting bent caps were designed during the Eisenhower interstate era of the 1950’s with the AASHO design equations at the time, which subsequently place higher demand on the concrete. The referenced components may exhibit diagonal cracking due to the...
The use of paraeducators has increased as a main mechanism to include more
students with disabilities in multiple settings in the public schools in the U.S.
Research has examined the use of paraeducators in typical classroom settings but
little is known about their role in physical education. Although the utilization...
Hydrodynamic models are used as a diagnostic tool to understand the temporal variability of shallow-water processes that are difficult to completely resolve with traditional field measurements. For all simulations, modeled quantities are qualitatively or quantitatively compared with available measurements to gain confidence in conclusions derived from the modeled results. In...
The purpose of this dissertation was to explore the experiences of Asian group leaders who were leading groups in Asia. This research was developed to address a need for exploratory research in the area of Asian group leaders' perceptions and experiences during the process of leading groups in Asia. Grounded...
The purpose of this dissertation was to explore the developmental experience of novice play therapists. A review of the play therapy training literature as well as the counselor development literature suggested that there are characteristics such as patience, flexibility, and a love for children that are needed to work with...
Non-destructive commercial ultrasonic grading provides laminated veneer lumber (LVL) manufacturers a means for sorting veneer based on average ultrasonic propagation time (UPT) and/or average dynamic modulus of elasticity (MOEd). While this may provide reliable estimations of modulus of elasticity (MOE), little is known about the influence of veneer defects on...
If P is an integer polynomial denote the degree of P by ∂(P) and let H(P) be the maximum of the absolute value of the coefficients of P. Define Λ(P)=2[superscript ∂(P)]H(P) and for a fixed prime p let C[subscript p] denote the completion of the algebraic closure of the p-adic...
A historic struggle in the counselor education field has been determining and developing the emotional suitability of applicants and trainees for counseling work. The literature suggests that emotional suitability for counseling includes such things as: the ability to experience a full range of emotions, the ability to modulate emotions,the ability...
This dissertation addresses issues of strategic behavior of firms in oligopoly markets. In the first study we analyze how generic advertising affects brand advertising and firm profits in differentiated oligopoly markets. We develop two models, one with vertical differentiation and another with horizontal differentiation. In the case of vertical differentiation,...
General purpose computer systems have seen increased performance potential through the parallel processing capabilities of multicore processors. Yet this potential performance can only be attained through parallel applications, thus forcing software developers to rethink how everyday applications are designed. The most readily form of Thread Level Parallelism (TLP) within any...
We examine the interactions and feedbacks between bathymetry, waves, currents, and
sediment transport. The first two pro jects focus on the use of remote sensing techniques
to expand our knowledge of the nearshore. Due to the plethora of snap-shot data that is
available from satellites and their distribution via Google...
For Pacific salmon, the evolution of local adaptations depends upon the species' propensity to return, or "home", to natal streams at time of reproduction. Pacific salmon use olfactory cues to guide homing behavior, yet little is known about the genetics of olfaction in salmon. In this study, I use putatively...
Kincaid's lupine (Lupinus oreganus Heller) is a federally listed threatened species native to remnant grassland of western Oregon and southwestern Washington, and is the primary larval host plant of a once thought extinct butterfly, Plebejus icarioides fenderi Macy. Past studies concerning Kincaid's lupine reproduction
suggested that populations may suffer reductions...
A study consisting of three parts was undertaken to investigate how variation in species interactions, population genetic structure, epidemiological parameters, and plant breeding system may influence the ecology and biological control of an apomictic invasive plant, Chondrilla juncea (Asteraceae). Interactions between natural enemy species may modify their net effect on...
Approximately 12% of Americans do not consume the amount of zinc equal to the Estimated Average Requirement for zinc and could be at risk for marginal zinc deficiency. Zinc is an essential component of proteins in the defense against oxidative stress and DNA damage repair. Specifically in the prostate, zinc...
This dissertation used land rent theory and an economic model of land-use conversion to examine the main drivers of the deforestation occurred in Antioquia,Colombia, between 1980 and 2000. Land-cover information at a semi-fine scale (1:25,000)
obtained largely from aerial photography was employed to calculate deforestation. In addition, free international databases...
Recently, the concept of performance based design has become popular for many types of structures, including port facilities under seismic loading. For the case of pile-supported wharves, the level of performance is generally estimated using the displacement capacity of the structure. Therefore, understanding soil-pile interaction is one of the most...
Society uses massive quantities of wood fiber in production of paper, and demand for fiber is projected to increase further as production of biofuels from fermentation of plant cellulosic materials increases. Because these end uses generally require the costly step of removing of lignin, wood with reduced or more easily...
In this dissertation, I qualitatively examined the meaning of mothering a child with autism in two countries: the United States and South Korea. The overarching research question focused on how sociocultural ideas about mothering and disability, particularly autism spectrum disorders, shape women’s understanding of themselves and their children with disabilities....
The emerging use of portable digital devices by students, parents and teachers, is forcing schools to develop real-time communication systems that integrate technology into the general operations of schools, and contemplate governing policies and procedures to sustain and guide the challenges of these new technologies. This study contributes to this...
Detection technique that proposed utilizing electrochemically controlled, reversible ion extraction into polymeric membrane in an alternating galvanostatic/ potentiostatic mode was introduced. This method is studied in detail to comprehend the advantages of the novel sensor (pulstrode) compared to the potentiometric ion selective electrode (ISE), studies included possible applications and limitations....
There is significant interest in titanium oxide and germanium-silicon oxide nanocomposites for optoelectronic, photocatalytic, and solar cell applications. The ability of the marine diatom Pinnularia sp. to uptake soluble metal oxides from cell culture medium, and incorporate them into the micro- and nano-structure of their amorphous silica cell walls, called...
Current detection methods for bacterial contamination rely on structure based detection of proteins and nucleic acids. While these methods are easy to use and reliable, they cannot evaluate the toxicity of a sample and the potential to cause disease. Previously, erythrophore cells derived from Betta splendens had been suggested as...
The purpose of the study was to determine if online courses that were faculty peer reviewed based on five factors of quality instruction resulted in increased levels of student satisfaction and higher rates of student retention when compared with nonreviewed courses in a post-secondary context. The five factors of quality...
Long-run food price changes respond to long-run changes in food demand, quasi-fixed and variable production factors, and agricultural productivity. Recent global food-price volatility puts a renewed spotlight on the trends and sources of any agricultural productivity growth. Because food prices’ most critical effects are on human hunger, it is especially...
Interconnection networks play important roles in designing high performance computers. Recently two new classes of interconnection networks based on the concept of Gaussian and Eisenstein-Jacobi integers were introduced. In this research, efficient routing and broadcasting algorithms for these networks are developed. Furthermore, constructing edge disjoint Hamiltonian cycles in Gaussian networks...
Why do rural households leave for urban places? And how does this
decision affect their economic well-being? Rural places in the United States have higher poverty and unemployment rates and lower levels of educational attainment relative to urban places. Does leaving a rural place for a city offer a pathway...
The primary purpose of this study was to determine which factors related to adult 4-H volunteer empowerment in 4-H youth development settings. This study examined the relationship of adult 4-H volunteers’ perceived leadership styles of Oregon 4-H Youth Development Educators (YDE) to the adult 4-H volunteer sense of empowerment. In...
Geometric Problems become increasingly intractable and difficult to visualize as the number of dimensions increases beyond three. Inductions from lower dimensional spaces are possible yet often awkward. This thesis shows how elementary linear algebra, vector calculus, and combinatorics offer improved methods for calculating the dihedral angles of n-simplicies and proving...
The absence of Black male counselor educators in CACREP accredited programs is astounding. Out of a pool of 130 CACREP programs, only 31 have at least one Black male full time counselor educator. Although these programs are comprised of approximately 2,000 counselor educators, only 58 of them are Black men....
A backward fall is a major cause of hip fractures. Hip fractures have the potential to increase the mortality rate of older adults. Thus, the prevention of backward falls by older adults is a critical subject to be studied. Specifically, it remains unknown what effect aging-related losses in muscle strength...
Clostridium perfringens is the causative agent of a wide variety of diseases in animals and humans. C. perfringens can produce more than 15 toxins. However, individual strains produce a subset of these toxins. Although a small percentage of C. perfringens isolates (mostly belonging to type A) produce C. perfringens enterotoxin...
Although female athletes are at greater risk of non-contact knee injuries than men, the factors that contribute to these injuries are not well understood. One important question is whether intense exercise influences the risk of knee injury, both acutely
and over the following days. The purpose of this study was...
The links between forests, streamflow, and climate are poorly understood. Despite hundreds of studies over the past 60 years, fundamental questions of forests' effects on the hydrologic cycle remain unanswered. The hydrological cycle involves mutually-dependent biological and physical processes that operate at multiple scales of time and space, and this...
COUP-TFI, an orphan nuclear receptor of the steroid/thyroid hormone receptor superfamily, plays important roles in homeostasis and the CNS development, including differentiation, patterning, axonal projection, cell migration, cortical arealization and the temporal specification of neural stem cells. A number of COUP-interacting proteins have been described previously, and the majority of...
The existence of generalized symmetries of Maxwell's equations in Gödel's Universe is investigated. It is shown that their existence is in turn tied to the existence of certain spinorial objects called Killing spinors.
The conformal algebra, corresponding to valence (1; 1) Killing spinors, for Gödel's Universe is discussed in detail....
The Department of Nuclear Engineering and Radiation Health Physics (NE/RHP) at Oregon State University (OSU) has been developing an innovative modular reactor plant concept since being initiated with a Department of Energy (DoE) grant in 1999.
This concept, the Multi-Application Small Light Water Reactor (MASLWR), is an integral pressurized water...
Until a few years ago, wireless-capable laptops were considered novelties by many. It is now hard to find a laptop or a hand-held computing device that is not wireless-ready. As wireless devices are becoming commodities, they have also become an indispensable part of the modern society. Not surprisingly, research in...
Approximately half of the 6.4 million pregnancies occurring each year in the
United States are unintended (Finer & Henshaw, 2006). Unintended pregnancies, defined
as pregnancies not wanted at the time conception occurs, regardless of contraceptive use
(Chandra, Martinez, Mosher, Abma, & Jones, 2005) can have serious repercussions on
women, children,...
Programmers spend a substantial fraction of their debugging time by navigating
through source code, yet little is known about how programmers navigate. With the
continuing growth in size and complexity of software, this fraction of time is likely to
increase, which presents challenges to those seeking both to understand and...
Oregon residents with a terminal illness have had the option to use aid-in-dying under the Oregon Death with Dignity Act (DWDA) since 1997. The DWDA allows terminally ill Oregonians to make a request for lethal dosages of medication, prescribed by physicians for the purpose of self-administering to end one's life....
This study investigates the hydrodynamic characteristics of droplet impinging on heated surfaces using High Speed High Resolution (HSHR) imaging and evaluates the effect of surface temperature and using water and a nanofluid on a polished and a nano-structured surface. Three types of surfaces are used in the
study: polished silicon,...
Contract harvest operations have become the preferred approach to reducing the largest cost component of timber production through free market competition amongst logging contractors bidding or negotiating for work. The goal of this research was to investigate economic components of harvesting operations not previously studied for steep slope thinning harvests...
Influenza A and Respiratory Syncytial Virus (RSV) are both enveloped, negative strand
RNA viruses which infect the respiratory mucosa of animals and humans. Despite
decades of research and development of antivirals and vaccines, both of these viruses
continue to be a major health concern throughout the world. The focus of...
Cephalosporium stripe (Cephalosporium gramineum) is an important disease limiting adoption of conservation tillage practices in the Pacific Northwest. The disease can cause severe loss of grain yield and quality in winter wheat (Triticum aestivum L.). Modified cultural practices can reduce disease incidence, but are not always dependable because of variation...
Chemoreception is one of the dominant sensory modalities for many species of salamanders (reviewed in Chapter 2). At least seven of the ten currently recognized salamander families are known to respond to some sort of chemical cue. These responses are as varied as delaying hatching, seeking refuge, or initiating aggressive...
Analysis, visualization, and design of vector fields on surfaces have a wide variety of major applications in both scientific visualization and computer graphics. On the one hand, analysis and visualization of vector fields provide critical insights to the flow data produced from simulation or experiments of various engineering processes. On...
Periodic metal and metal-dielectric composite nanostructures have been of interest from the field of plasmonics and metamaterial fabrication. In order to exploit the behavior of these unique materials in the visible region of the optical spectrum, these structures need to be significantly shorter than the wavelength of response, and hence...
The purpose of this study was to explore the possible relationship among fashion media, the social responsibility agenda of the Audubon Society, and the use of birds in millinery in the late nineteenth and early twentieth centuries. Both the content analysis method and the historic method were used to gain...
The 2-ka eruption of Misti volcano produced voluminous flowage deposits and a wide-spread tephra-fall deposit. The flowage deposits form large terraces within channels draining the south side of the volcano. All the channels drain into the city of Arequipa. Arequipa's city center is ~16 km from the summit of the...
A Diels-Alder approach to biaryls (DAB) has been applied towards the synthesis
of highly substituted, programmable biaryl templates. Tri- and tetra-ortho-substituted
biaryls can be produced in just three to four steps from commercially available materials
utilizing the Diels-Alder [4+2] cycloaddition. The methods described herein will
illustrate the ability of mono...
We have developed a compact micro total analysis system (μTAS) to serve as a platform for in-situ spectrophotometric water quality monitoring. Individual fluidic, optical, and electrical components were designed, developed, and characterized. These components were combined in both an integrated (single lithographic “chip-based” platform) and a modular manner. The microfluidic...
Academic achievement of adolescent children is directly associated with their success in adulthood. Little is known, however, regarding how adolescents in immigrant families academically grow over time and what factors influence the trajectories. Drawing on the National Educational Longitudinal Survey 1988 (NELS: 88), this study aimed to: 1) identify the...
Prostate cancer risk is significantly lower in Asian countries compared to the US, which has prompted interest in the chemo-preventative action of dietary components such as soy and green tea commonly found in Asian diets, such as soy and green tea. Studies have suggested that soy isoflavones and green tea...
Sequential supervised learning problems arise in many real applications. This dissertation focuses on two important research directions in sequential supervised learning: efficient training and feature induction.
In the direction of efficient training, we study the training of conditional random fields (CRFs), which provide a flexible and powerful model for sequential...
Although perceived-risk curriculum, that is, where the learner experiences effects of eustress (positive stress), has been used in Arts or outdoor activities, it has not been used in school classrooms. Milkman’s 1996 studies of after-school Project Self Discovery demonstrated that at-risk students lessened their adverse risky behaviors, such as substance...
Many species have complex life cycles in which a dispersive larval stage is
followed by a relatively sedentary adult stage. For such species, reproductive output
is often high and large variation in survivorship throughout early life-history phases
(eggs and larvae) can lead to dramatic fluctuations in recruitment which may in...
Many animals detect prey or enhance their locomotion with information from hair-like receptors that are activated by local fluid flows. The utility of biological hair receptors has motivated the design of artificial hair sensors (AHS) for flow control applications where aerodynamic or hydrodynamic forces play a significant role in the...
Rubus seed characteristics; seed coat morphology, anatomy, germination requirements and dormancy were studied in order to define protocols for breaking seed dormancy. Morphological analysis of the seed coat (testa) using scanning electron microscopy (SEM) included 56 seed accessions of 10 subgenera preserved in the collections of the US Department of...
Oxidative stress occurs when the balance between reactive oxygen species and antioxidant defense mechanisms in the body becomes tipped heavily in favor of the reactive oxygen species. Reactive oxygen species can be present in excess due to elevated O2 levels, radiation, infection, smoking, or even excessive exercise. It is also...
Herbs have been used for many centuries in diverse civilizations for the treatment of heart disease. Only a few natural supplements claim to have direct cardiovascular actions including hawthorn (Crataegus spp.) and berberine derived from the Berberidaceae family. Several different studies indicate important cardiovascular effects of hawthorn and berberine. For...
This thesis includes three studies involving different aspects of modeling protein structure. The first study illustrates the levels of insight available from atomic-resolution protein structures. The second study derives general trends of protein geometry from atomic-resolution structures and shows their implications for modeling. The third study creates a model of...
The structural architecture present in marine toxin azaspiracid - 20 stereocenters, 9 rings, 3 separated spirocenters - has attracted considerable synthetic attention. Our efforts toward the synthesis of azaspiracid have led to the completion of both C₁-C₂₆ northern and C₂₇-C₄₀ southern halves. Herein, the
synthesis of southern FGHI ring system...
This dissertation explores the idea of applying machine learning technologies to help computer users find information and better organize electronic resources, by presenting the research work conducted in the following three applications: FolderPredictor, Stacking Recommendation Engines, and Integrating Learning and Reasoning.
FolderPredictor is an intelligent desktop software tool that helps...