Although electronic medical records systems (EMR) present promising benefits, they have not yet been widely adopted. A problem facing many EMR are that they are disruptive technologies; their complex hardware and software are not designed to account for the clinicians' characteristics and needs, thus, demanding a steep learning curve and...
Knot Theory: In Imitation of Lewis Thomas is a collection of 14, 1200-word essays written in the style of Lewis Thomas, a physician who regularly contributed to The New England Journal of Medicine. His 1200-word column, "Notes of a Biology Watcher," ran from 1971 - 1980. The resulting compilations collectively...
Since the introduction of lean manufacturing by Toyota and publication by Womack and Jones, organizations have realized sizeable gains through lean process improvement. The spread of lean practices across organizations and industries – from manufacturing to healthcare and construction – requires adjustments of the lean process and, in the case...
Macrosomia is a medical term describing a new baby born with an excessive birth weight (greater than 4000g). Fetal macrosomia may lead to both pregnancy complications, and increased risk of mother's and baby's health problems after birth. But the potential complications may be mitigated by a cesarean delivery. As such,...
Charge transport in a semiconductor structure with heterojunction is described by a multiscale partial differential equation model. This model can be used, e.g., for the design of more efficient solar cells. Phenomena at the heterojunction must be resolved at the angstrom scale while the size of the device is that...
Sensors find a variety of applications in portable electronics, automotive and biomedical solutions. The demand for low power and high dynamic range makes the design of digital sensor readout circuits quite challenging. Traditionally, these circuits are realized using amplifiers with passive feedback or precision analog comparators which are power hungry...
Multiple drug resistance (MDR) Tuberculosis (TB), leads to increased use of “second-line” drugs; one of the most effective is ethionamide (ETA). ETA is a prodrug metabolized by a mycobacterial flavin-containing monooxygenase (EtaA) as well human flavin-containing monooxygenases (FMOs). Of the five functional FMOs of humans, FMOs 1, 2, and 3...
Easy-first, a search-based structured prediction approach, has been applied to many NLP tasks including dependency parsing and coreference resolution. This approach employs a learned greedy policy (action scoring function) to make easy decisions first, which constrains the remaining decisions and makes them easier. This thesis studies the problem of learning...
In the last decade, the California Current Large Marine Ecosystem has experienced a trend of increased severity of upwelling-driven coastal hypoxia. This thesis strove to examine the potential upper trophic level impacts of moderate and severe hypoxia in the CCLME. Initially I conducted a literature review of Pacific harbor seal...
Amorphous metal thin films (AMTFs) are of potential use for metal-insulator-metal (MIM) tunnel diode applications due to their ultra-smooth surfaces, a consequence of their amorphous microstructure. The objective of this thesis is to design a thermally-stable AMTF capable of maintaining MIM tunnel diode performance after a post-deposition anneal in excess...