The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
The economically viable production of value added fuels and chemicals from lignocellulosic feedstocks hinges on our ability to quickly and efficiently transform structural carbon molecules to end products. The sugars in lignocellulosic biomass are held primarily within cellulose and hemicellulose. Cellulose is composed primarily of glucose monomers which are quickly...
Atmospheric pressure changes do not stop at the permeable snow surface but rather propagate into it. These pressure changes range from high-amplitude, low-frequency events caused by seasonal cycles and synoptic weather systems to small-amplitude, high-frequency events caused by topographic features and turbulence. The effect of pressure changes on interstitial air...
When hops are added to beer, varying degrees of hoppy aroma persist in the finished beer as a result of a number of factors. Dry-hopping is a technique whereby hops are added to beer post-fermentation to leverage the maximum aroma potential of the hop essential oils while minimizing bitterness contribution...
Student engagement with faculty is positively associated with increases in the retention and graduation rates of students enrolled in institutions of higher education. Although a considerable amount of research has focused on understanding the engagement experiences of students enrolled at four-year colleges and universities, little emphasis has been placed on...
Plethodontid salamanders have served as an informative vertebrate system for studying the role of chemical signals in facilitating social and reproductive behaviors. Individuals produce complex mixtures of chemicals from multiple glandular regions. In total, these secretions convey a wide variety of information, and are important for numerous inter- and intraspecific...
Although only a minority of introduced species become established and have noticeable consequences in their new communities, some can displace native species, alter food webs, and cause local extinctions. Studying these invasive species can provide new insights into basic ecological questions as well as inform management strategies. Pacific lionfish (Pterois...
Biological invasions have been identified as one of the prominent drivers of global environmental change. In particular, invasive predators typically have substantial negative effects on populations of native prey, even driving species to extinction in extreme cases. However, beyond direct predatory effects, little is understood regarding the specific mechanisms by...
Red clover (Trifolium pratense L.) seed yield can be affected by plant growth regulators (PGR) and irrigation; however, the effects of these factors on physiological maturity (PM), harvest maturity (HM), and seed quality are unknown. The objectives of this study were to: 1) determine how irrigation and trinexapac-ethyl (TE, a...
There are many links between exposure to environmental pollution and risks to human health. While advances in the fields of toxicology, exposure science, and environmental chemistry have shown light on many of these links, many more research challenges remain. One major challenge is how to accurately characterize the toxicity of...
Multiple Sclerosis (MS) is an autoimmune condition that affects the central nervous system, and impacts the lives of over 400,000 individuals in the US. These individuals face unpredictable relapses of disabling conditions, are less active and experience poorer quality of life than the general population. Health professionals are challenged to...
The implementation and construction of Mechanically Stabilized Earth (MSE) walls has undergone substantial expansions in recent years, owing to its relatively low cost, ease of construction, and high efficiency compared to conventional retaining methods. As a result, MSE walls are being constructed to greater heights with complex features (e.g. multiple...
The multifaceted role of the environment in regulating the structure and dynamics of biological communities has long fascinated ecologists and motivated much debate and research. Now, in a time of accelerated global changes due to human impacts, the need to understand how the environment shapes communities has gained new urgency....
There is increasing awareness that human activities are altering the ways that natural systems operate and that local shifts in species composition and abundance can lead to abrupt and irreversible global change. Therefore, understanding the processes that buffer biological communities from critical shifts and how our actions affect natural stabilizing...
The goal of dissertation research was to use geochemical, statistical and geological methods to constrain and understand climate variability over several different time scales. Specifically, I have addressed three questions regarding past climate change: (1) how does the record of Irish cirque glaciers constrain the dimensions of the Irish Ice...
Despite more than two centuries of exploration, including more than six million deep wellbores with depths exceeding 40,000 feet in some parts of the world, our ability to constrain subsurface processes and properties remains limited. Characteristics of the subsurface vary and can be analyzed on a variety of spatial scales....
Today nano scale materials are being used for wide range of applications. One promising topic in nano scale materials is using them for reinforcement of different polymeric materials to reach desirable stiffness properties. The stiffness of these materials is mostly found experimentally because the nanocomposite community lacks a decent analytical...
Energy consumption has become a great deal for cloud service providers due to financial as well as environmental concerns. Studies show that cloud servers operate, most of the time, at only between 10% and 50% of their maximal utilizations. These same studies also show that servers that are kept ON...
Cognitive radio technology emerges as a promising solution for overcoming shortage and inefficient use of spectrum resources. In cognitive radio networks, secondary users, which are users equipped with cognitive radios, can opportunistically access spectrum assigned to primary users, the spectrum license holders. Although it improves spectrum utilization efficiency, this opportunistic...
The rapid scaling of network bandwidth and data center throughput has motivated the wide adoption of high speed transceivers. Silicon photonics (Si-Photonic) is one of the most promising techniques to realize tightly integrated optical transceivers for next-generation high speed I O standards. This dissertation focuses on the design techniques of...