Group Engagement Theory describes the relationship between citizen perceptions of policy, individual identity and status judgements, and individual group engagement decisions. Utilizing a least likely crucial case methodology, this paper uses the case of Josephine County, Oregon to determine the validity of the Group Engagement Theory prediction that citizen identity...
Background:
The language of “participant-driven research,” “crowdsourcing” and “citizen science” is increasingly being used to encourage the public to become involved in research ventures as both subjects and scientists. Originally, these labels were invoked by volunteer research efforts propelled by amateurs outside of traditional research institutions and aimed at appealing...
In 2005, riots spread throughout urban peripheries of large French cities known as banlieues. Once the flames of burning cars and the smoke of teargas dissipated, experts began to question the causes that brought France into a state of emergency. The term banlieue describes suburb tower housing post-World War II...
There are more than 87,000 chemicals in current use with little to no toxicity information available. Assessing such a large number of chemicals using traditional methods would take an unreasonable amount of time and money, and require the use a large number of animals. The incorporation of high-throughput in vivo...
This research examines the literary and philosophical dimensions of the African American Harlem Renaissance, beginning with the historical milieu of the early twentieth century. A social movement that became known as Uplift and the so-called Cabaret Movement emerged as important, competing literary and social ideologies within the Renaissance. W.E.B. Du...
The seasonal climate drivers of the carbon cycle in tropical forests remain poorly known, although these forests account for more carbon assimilation and storage than any other terrestrial ecosystem. Based on a unique combination of seasonal pan-tropical data sets from 89 experimental sites (68 include aboveground wood productivity measurements and...
Accurately monitoring tropical forest carbon stocks is a challenge that remains outstanding. Allometric models that consider tree diameter, height and wood density as predictors are currently used in most tropical forest carbon studies. In particular, a pantropical biomass model has been widely used for approximately a decade, and its most...
African American male students are a small portion of the student body at NCAA Division 1-A schools, but they make up a large portion of population of college football players. African American male college students are also one of the most at-risk student populations on campus in regards to retention....
A year-long bench-scale treatability study was performed to assess the feasibility of using an activated sludge sequencing batch reactor (SBR) to treat a mixture of domestic wastewater and landfill leachate. A 50/50 (v/v) of domestic wastewater and landfill leachate was treated in a 1 L SBR operated on a 12...
Global warming is becoming an increasingly important environmental concern and CO₂ is considered as the major cause of global warming. Creating useful applications for CO₂ would generate alternatives to merely venting CO₂ to the atmosphere, and decreasing the carbon intensity of human activities. Among various methods of CO₂ utilization, conversion...
Pumping water from coal seams decreases the pressure in the seam and in turn releases trapped methane; this is the most common and economic method of methane extraction. The water that is pumped out is known as "coal-bed methane water" (CBMW), which is high in sodium and other salts. In...
A novel approach for the colorimetric detection of creatinine in a paper/polycaprolactone hybrid microfluidic device using alkaline3,5-dinitrobenzoate (DNB) is described. The reaction parameters of reagent concentration, alkalinity, and analysis time are optimized for fast reaction times and high color yield. Microfluidic devices incorporating this assay are designed and fabricated to...
Despite widespread public support for renewable energy development, the siting of wind energy facilities can prove problematic due to opposition from surrounding communities. I propose a unifying framework to explain community response to wind energy development – showing how concepts from environmental sociology related to local biophysical and socioeconomic conditions...
Background:
Over 650 million people worldwide lack access to safe water supplies, and even among those who have gained access to ‘improved’ sources, water may be seasonally unreliable, far from homes, expensive, and provide insufficient quantity. Measurement of water access at the level of communities and households remains crude, and...
Transcriptome and genome data from twenty stony coral species and a selection of reference bilaterians were studied to elucidate coral evolutionary history. We identified genes that encode the proteins responsible for the precipitation and aggregation of the aragonite skeleton on which the organisms live, and revealed a network of environmental...
The advent of improved DNA sequencing technologies has allowed the analysis of various microbial communities. Bloom-forming freshwater cyanobacteria can produce toxins and taste-and-odor compounds that can negatively affect drinking water supplies. Here, I have employed second- and third-generation sequencing technologies to characterize bloom-forming freshwater cyanobacterial genomes and their associated heterotrophic...
Dermatological issues are a widespread problem in humans that are often
overlooked. In our present study, we have isolated lipids from de-identified epidermal
skin tape samples from both Atopic Dermatitis and healthy individuals using a high
efficiency one-step extraction method, which were subsequently analyzed using modified
Liquid chromatography–mass spectrometry (LC-MS)....
Often, characters of entertainment works, such as movies, books, or video
games, display traits that people find relatable. In certain cases, a spectator of a work
will develop such a strong psychological bond with a character that they identify with
them. Identification with fictional characters is usually a subconscious act...
The purpose of this study was to compare the child behaviors of young children with autism spectrum disorder (ages 44-91 months) in different play settings. The hypothesis states that more positive child behaviors will be observed in the motor-based play setting compared to the free play setting. This study observed...
Recently, there has been peaked interest in developing high energy producing and optimized power take-off topologies for Wave Energy Converters (WEC). As large as the potential of the oceans may seem, harnessing that energy and effectively converting it to electricity in significant amounts is a challenge. Currently, there are no...
In this thesis we construct compatible discretizations of Maxwell's equations. We use the term compatible to describe numerical methods for Maxwell's equations which obey many properties of vector Calculus in a discrete setting. Compatible discretizations preserve the exterior Calculus ensuring that the divergence of the curl and the curl of...
A three-dimensional, process-based model of the ocean’s carbon and nitrogen cycles, including 13C and 15N isotopes, is used to explore effects of idealized changes in the soft-tissue biological pump. Results are presented from one preindustrial control run (piCtrl) and six simulations of the Last Glacial Maximum (LGM) with increasing values...
All ecosystems are subjected to chronic disturbances, such as harvest, pollution, and climate change. The capacity to forecast how species respond to such press perturbations is limited by our imprecise knowledge of pairwise species interaction strengths and the many direct and indirect pathways along which perturbations can propagate between species....
The state of Oregon is divided in important ways along rural and urban lines, including the way people make a living, individual and group relationships with the natural world, political ideologies, and personal values. This rural-urban divide has assisted policymakers in making decisions that balance the needs of Oregonians on...
Clashes of ideology are all around us, from our computer and television screens to our composition classrooms, and they merit attention within the composition classroom. This thesis examines the justifications and pedagogies that scholars in rhetoric and composition use to infuse issues of ideology and social ethics into writing instruction...
Designing a carbon fiber chassis for the Global Formula Race car has historically proven to be both time intensive and difficult. The goal of this thesis is to improve the design process for testing Global Formula Racing team's composite chassis sandwich panels. Consideration was taken regarding Formula SAE rules, and...
Conspectus:
The flexibility, complexity, and size of contemporary organocatalytic transformations pose interesting and powerful opportunities to computational and experimental chemists alike. In this Account, we disclose our recent computational investigations of three branches of organocatalysis in which nonbonding interactions, such as C–H···O/N interactions, play a crucial role in the organization...
Vacuum arc remelting (VAR) is a secondary melting process for exotic alloys. The main purpose of this process is to increase the input ingot’s physical and chemical homogeneity. This is accomplished through the application of a high current that melts the material through the emergence of electrical arcs that induce...
Whether media plays a contributory or a conduit role in the policy process has been a salient focus among policy scholars. If media plays a contributory role in the policy process, it not only shares similar policy core beliefs with advocacy coalitions, but also drafts and disseminates stories including policy...
Most of the policy debate surrounding the actions needed to mitigate and adapt to anthropogenic climate change has been framed by observations of the past 150 years as well as climate and sea-level projections for the twenty-first century. The focus on this 250-year window, however, obscures some of the most...
Users interested in customizing their Primo installation are required to configure specific settings, files, and code during the View setup process. A consequence of this is that unique customizations are not easily sharable between institutions. With the release of the new Primo User Interface, Ex Libris has enabled institutions to...
The construction of the first genetic map in autotetraploid blueberry has been made possible by the development of new SNP markers developed using genotyping by sequencing in a mapping population created from a cross between two key highbush blueberry cultivars, Draper × Jewel (Vaccinium corymbosum). The novel SNP markers were...
This is an open access article published under an ACS AuthorChoice License, which permits copying and redistribution of the article or any adaptations for non-commercial purposes.
Non-starter lactic acid bacteria (NSLAB) are found at low levels in fresh raw milk and are important to the dairy industry because of their potential impact on the flavor and texture of yogurt, sour cream, and cheese. The purpose of this study was to evaluate three methods for the identification...
Pantoea vagans C9-1 (C9-1) is a biological control agent sprayed onto apple and pear trees during bloom for suppression of fire blight, a devastating bacterial disease caused by Erwinia amylovora. Prior bioinformatics studies of C9-1 focused on predicted phenotypes associated with the three native megaplasmids, pPag1, pPag2, and pPag3, and...
The Pacific coast sea anemone Anthopleura elegantissima is an excellent model organism for the study of temperate symbiosis due to its unique relationship with two microalgal symbionts, Elliptochloris marina and Symbiodinium spp. In addition to hosting one or both of these symbionts, A. elegantissima can live aposymbiotically, allowing for the...
Current protein immobilization techniques lack defined control over protein orientation. Protein orientation is important for making biosensors and biomaterials that are sensitive and efficient and can be crucial for designing some devices such as immunosensors or direct electron transferring biocells. A new method of protein immobilization is proposed that takes...
Hydrology is the main environmental filter in aquatic ecosystems and may result in shared tolerances and functional traits among species in disparate ecosystems. We analyzed the associations between taxonomic and functional facets of diversity within aquatic ecosystems (ponds vs. streams) across a hydroperiod gradient (1–365 d) to untangle the hydrologic...
This study is an investigation into the roles of wildfire and changing agricultural practices in controlling the inter-decadal scale trends of suspended sediment production from semi-arid mountainous rivers. In the test case, a decreasing trend in suspended sediment concentrations was found in the lower Salinas River, California between 1967 and...
This study was interested in determining whether vocal communications or facial expressions and body language are more effective in communicating positive, neutral or negative affects when used in isolation and without deception. A sample of six male and six female (n = 12) students in Dr. Bernieri’s Winter term 2016...
This study investigates the relationship between total and ionic copper in samples taken from the Tualatin River and wastewater treatment facilities (WWTFs) that discharge into the Tualatin River. Copper speciation was analyzed by determining conditional stability constants and densities of copper binding ligands on the dissolved organic matter (DOM) in...
Software Defined Storage is a term for data storage software to manage policy-based provisioning and management of heterogeneous data storage system abstracting underlying hardware. CoprHD is a software defined storage controller and API platform which enables policy-based management and cloud automation of storage resources for block, object and file storage...
The corrosion behaviors of carbon and stainless steels were investigated in supercritical CO₂ (sCO₂ ) containing H₂O and O₂ simulating conditions that exist in direct sCO₂ power cycle heat exchangers. Thermodynamic properties of CO₂-H₂O-O₂ systems related to the corrosion phenomena were determined using NIST software. The exposure tests of the...
Schistosomiasis is a neglected tropical disease caused by parasitic trematodes in the genus Schistosoma. 200 million people are infected with schistosomes. Schistosomiasis causes acute and chronic disease, and may lead to death in chronic infections. Schistosomes have a complex life cycle that requires passage through a snail intermediate host. Understanding...
In the wake of nuclear accidents such as Three Mile Island Unit 2 and Fukushima, the nuclear power industry’s safety record is scrutinized. Today the main concerns lies with hydrogen production in a nuclear reactor core when the zirconium fuel cladding reacts with the water coolant during an accident, creating...
This study computationally and experimentally examines the mechanisms of crack penetration, deflection and the transition between penetration and deflection. The finite element analysis based computational modeling work used strength-and-energy based cohesive-zone approach to study the effect of dimensionless parameters (e.g., interfacial incident angle, fracture-length scale, and normalized toughness) on penetration/deflection...
This article presents Oregon State University’s experience launching an innovative Open Textbook initiative in spring 2014. The partners, Open Oregon State and the Oregon State University Libraries and Press, aimed to reduce the cost of course materials for students while ensuring the content created was peer-reviewed and employed multimedia capabilities....
Over the past decade the International Commission on Radiological Protection has developed a comprehensive approach to environmental protection that includes the use of Reference Animals and Plants (RAPs) to assess radiological impacts on the environment. For the purposes of calculating radiation dose, the RAPs are approximated as simple shapes that...
Although Latino students make up more than a quarter of the U.S. public school system, only three percent of children’s literature either features a Latino protagonist or is written by a Latino author (Machado et al.). Latinos are therefore severely underrepresented in children’s books. Additionally, studies have revealed that Latino...
The goal of this project was to write a children’s book featuring same-sex and interracial families for children to both see themselves represented as well as to expose others to diverse, and increasingly common, family types. The creation of the book was guided by an analysis of the books available...
Measuring surface heat flow at the Hikurangi Trough is key toward characterizing the local thermal regime and the influence of thermally sensitive processes such as fluid flow and slow slip. Marine heat flow data were collected during May– June 2015 in the northern Hikurangi Trough at sites seaward and landward...
Crystal morphology and dimensionality of single-crystal semiconducting materials can have dramatic effects on the optical and electrical properties. Organic photovoltaic (OPV) materials and fluorinated graphene folds are two materials that show these dependencies. Anthradithiophene (ADT), is an OPV that can be functionalized with different side groups to form different crystal...
Wildfire greatly impacts the composition and quantity of organic carbon stocks within watersheds. Most methods used to measure the contributions of fire altered organic carbon–i.e. pyrogenic organic carbon (Py-OC) in natural samples are designed to quantify specific fractions such as black carbon or polyaromatic hydrocarbons. In contrast, the CuO oxidation...
The purpose of this dissertation was to add to the professional literature in counselor education and supervision through inquiry and synthesis of research among online teaching, online counseling, and online communities of practice through the supervision lens of the Discrimination Model. A unique, research-informed framework for synchronous online supervision (i.e.,...
Utilizing Danio rerio (zebrafish) as a model organism has gained popularity recently, however a lack of research into their immune response pathways had led to the discovery of subclinical infections, and has potentially confounded results. We conducted a study to determine the cytokine expression from TLR activation in order to...
Autonomous multiagent teams can be used in complex exploration tasks to both expedite the exploration and improve the efficiency. However, use of multiagent systems presents additional challenges. Specifically, in domains where the agents' actions are tightly coupled, coordinating multiple agents to achieve cooperative behavior at the group level is difficult....
This thesis is an illustrated look at my own everyday experiences with depression. By exposing the personal aspects of the symptoms, I hope to help contribute to society’s understanding of depression as a whole. Art in particular provides us an avenue unlike any other to express ourselves, and doing so...
Dead or Less Himself is a novel concerning creative impotence and the ways in
which people become repressed and stagnate through expectation, isolation, and over-analyzing. The novel takes place across high school to chart the ways the characters
change or refuse to change as they “grow up.” The novel is...
Dissolved organic matter (DOM) in the oceans is one of the largest pools of reduced carbon on Earth, comparable in size to the atmospheric CO₂ reservoir. A vast number of compounds are present in DOM, and they play important roles in all major element cycles, contribute to the storage of...
Arctic soils are warming, making vast stores of organic carbon available for conversion to CO₂. This could create a positive feedback loop and accelerate global warming, but the processes that convert this carbon into CO₂ are not well understood. We investigated how the combined activities of sunlight and microbes degrade...
The aim of this research is to develop a fundamental understanding of the dominant defect species and the relevant defect equilibrium conditions for bismuth-containing perovskites to help guide the development of these materials for emerging applications. This is of paramount importance for many demanding applications, because ultimately the defect equilibria...
Rebuilding of some U.S. West Coast rockfish (Sebastes spp.) stocks relies heavily on mandatory fishery discard, however the long-term condition of discarded fish experiencing capture-related barotrauma is unknown. We conducted two studies designed to evaluate delayed mortality, physical condition,and behavioral competency of yelloweye rockfish, Sebastes ruberrimus, experiencing barotrauma during capture...
The dipyridophenazine (dppz) based ruthenium polypyridyl complexes are known as molecular ‘light-switches’ for DNA. This property is poised to serve in diagnostic and therapeutic applications, but the poor cellular uptake restricts their use in live cells. Herein, we show that the cellular uptake, and more interestingly and surprisingly, the nuclear...
Federally listed as threatened in 1990 primarily because of habitat loss, the northern spotted owl (Strix occidentalis caurina) has continued to decline despite conservation efforts resulting in forested habitat being reserved throughout its range. Recently, there is growing evidence the congeneric invasive barred owl (Strix varia) may be responsible for...
Since the decimation of the southern right
whale Eubalaena australis population in New Zealand by
whaling, research on its recovery has focused on the wintering
ground at the Auckland Islands, neglecting potentially
important wintering habitat at Campbell Island. For
the first time in 20 years we conducted an expedition to...
Wireless localization of objects is useful for several applications that require the knowledge
of position of objects or people. Additionally, power extraction from wireless
signals eliminates the need for wires or any physical connections for charging. This
project is based on system-level testing of an integrated circuit (IC) that combines...
Fischer-Tropsh Synthesis is a chemical process that converts CO and H₂ (syngas) into long stable hydrocarbon chains to use as fuel. This process suffers from large product distribution that requires expensive post processing. In this study, the reaction mechanism of hydrocarbon chain growth on Co is investigated on different surface...
The ability to jump allows small robots to traverse rough terrain, clear large obstacles, and quickly reach elevated locations. These abilities have applications in a variety of areas such as, search and rescue, environmental monitoring, and urban warfare. The primary focus in current state-of-the-art jumping robots has been on jumping...
This work presents the design and implementation of a low power phased-array receiver frontend at 28 GHz in 65 nm CMOS. The frontend incorporates a low- power low-noise amplifier(LNA) and a passive reflection-type phase shifter (RTPS) capable of providing 360° phase shift with 5-bit phase resolution and low loss variation....
Miniature satellites called cubesats have been gaining increasing popularity in
both academic and private spaceflight ventures. NASA's Jet Propulsion Laboratory
has recently been accepting design proposals for a cubesat mission to Europa, where
solar and battery power would be inadequate power sources. In this thesis, a
radioisotope powered cubesat was...
An enabling technology for long duration, deep space missions is the availability of a high power, long-lived power supply. The goal of this work is the design of a self-regulating deep space nuclear reactor. The design objectives are to produce 250 kWth for a 25-year period using the presence of...
This thesis is the combination of two research publications working toward a unified strategy in which the design of complex engineered systems can be completed using a multiagent coordination approach. Current engineered system modeling techniques segment large complex models into multiple groups to be simulated independently. These methods restrict the...
Assembly time estimation is a key factor in evaluating the performance of the assembly process in an automated assembly process. The overall goal of this study is to develop an efficient assembly time estimation method by generating the prediction model from an experimental design. In order to estimate these times,...
The rapid scaling of network bandwidth and data center throughput has motivated the wide adoption of high speed transceivers. Silicon photonics (Si-Photonic) is one of the most promising techniques to realize tightly integrated optical transceivers for next-generation high speed I O standards. This dissertation focuses on the design techniques of...
This dissertation consists of a set of three manuscripts exploring features of effective professional development (PD) for science teacher educators. Literature about context-specific PD for science teacher educators is sparse. The first manuscript, a literature review, outlines theoretical lenses through which PD can be understood, the features of effective PD,...
Utilization and preference of whelk shells by the hairy hermit crab are examined in the following to further define the ecology of Oregon’s mid to low intertidal ecosystems. The study was conducted at Tokatee Kloochman State Natural Area (TK) where I made observations before collecting data. My observations were of...
The cereal cyst nematode Heterodera avenae reduces wheat yield in the Pacific Northwest. Resistance and tolerance traits among spring wheat cultivars were poorly defined. Screening trials were conducted with 39 cultivars over a 2-yr period in irrigated commercial fields that were infested by H. avenae. Comparisons were made between drill...
Koi herpesvirus (KHV) is highly pathogenic to Cyprinus carpio. KHV can also become latent in recovered fish and reactivate from latency under stressful conditions. Understanding KHV latency is important for development of strategies against herpesvirus latent infection. Our previous studies found KHV ORF6 mRNA is detectable during latent infection. In...
Human African trypanosomiasis (HAT), transmitted by tsetse flies, has historically infected hundreds of thousands of individuals annually in sub-Saharan Africa. Over the last decade, concerted control efforts have reduced reported cases to below 10,000 annually, bringing complete elimination within reach. A potential technology to eliminate HAT involves rendering the flies...
The National Conference of State Legislatures NCSL declares that 29 states have
been active in adopting and increasing renewable portfolio standards. Present
renewable portfolio standards require utilities to increase integration of renewable
energy sources such as photovoltaic (PV). The increased penetration of PV systems
is expected to destabilize the power...
The purpose of this thesis was to determine if an underlying biological cause exists for the exuberant reproductive success in free-roaming unowned (FRU) cats. The hypothesis for this thesis was that FRU tom and queen cats have reproductively adapted to man-made sterilization efforts by lowering the age at which they...
Biomass estimates are required for reporting carbon, assessing feedstock availability, and assessing forest fire threat. We developed diameter- and height-based biomass equations for Western hemlock (Tsuga heterophylla (Raf.) Sarg.) and red alder (Alnus rubra Bong.) trees in Western Oregon. A system of component biomass equations was fitted simultaneously with a...
Today nano scale materials are being used for wide range of applications. One promising topic in nano scale materials is using them for reinforcement of different polymeric materials to reach desirable stiffness properties. The stiffness of these materials is mostly found experimentally because the nanocomposite community lacks a decent analytical...
The National Research Council has aggregated research evidence on the pedagogy of science teaching and learning (NRC, 2012), culminating in the Next Generation Science Standards (NGSS). These standards support emphasis on eight scientific practices as an important component for teaching science as inquiry to K-12 students. This latest framework for...
Research on the population genetics of microbial organisms requires the use of specialized analyses designed for clonal organisms to avoid violating the assumptions of traditional population genetic models. The tools necessary for performing these analyses existed as a set of unrelated software with non-overlapping capabilities and did not cover all...
A system for radiological dosimetry for nonhuman biota developed by International Commission on Radiological Protection (ICRP) relies on calculations that utilize the Monte Carlo simulations of simple, ellipsoidal geometries with internal radioactivity distributed homogeneously throughout. In this manner it is quick and easy to estimate whole-body dose rates to biota....
Recent opportunities for new hydropower generation in the United States have often been in non-powered dams and run-of-river type flows occurring in low-impact natural areas and unregulated conduits. At the same time, a changing water resource paradigm is challenging some existing generation in drought stricken areas where supply reservoirs behind...
The discovery of novel compounds with antibacterial properties continues to be critically important.3 One potential source of such compounds is the cryptic genome of fungi known to produce biologically active molecules. A kmt6 mutant of the cereal pathogen Fusarium graminearum was previously developed through a histone H3 lysine 27 methyltransferase...
Here we report a new transgenic expression system by combination of liver-specific expression, mifepristone induction and Cre-loxP recombination to conditionally control the expression of oncogenic kras[superscript]V12. This transgenic system allowed expression of kras[superscript]V12 specifically in the liver by a brief exposure of mifepristone to induce permanent genomic recombination mediated by...
Agrobacterium tumefaciens causes the economically important plant disease, crown gall. These galls are the result of abnormal growth that manifests itself on either the root or the stem and can be devastating for the ornamental plant industry. Introduction of A. tumefaciens to a nursery can be highly detrimental and thus...
Phenylketonuria (PKU) is a genetic inborn metabolic disorder which inhibits the functional production of the enzyme phenylalanine hydroxylase (PAH). It currently affects one in 15,000 Americans and is the most common amino acid metabolism error found in newborns. Individuals affected with PKU are incapable of metabolizing the amino acid, phenylalanine...
Laboratory-based testing does not allow for the sufficiently rapid return of data to enable optimal therapeutic monitoring of patients with metabolic diseases such as phenylketonuria (PKU). The typical turn-around time of several days for current laboratory-based testing is too slow to be practically useful for effective monitoring or optimizing therapy....
The National Pesticide Information Center (NPIC) is a cooperative agreement between Oregon State University and the U.S. Environmental Protection Agency that offers science-based information about pesticides and related topics to the general public, medical personnel, applicators, researchers, and regulators. The Herbicide Properties Tool project is the creation of an updated...
Human body flight is a relatively young sport with a largely undocumented history.
Human body flight is an umbrella term for any sport involving maneuvering one’s body in a
meaningful way through a column of relative wind. Human body flight includes skydiving,
which was the origin of human body flight,...
Three distinct methods to achieve the stereoselective synthesis of carbon-carbon bonds were investigated, encompassing: (i) the formation of axially chiral biaryl molecules by enantioselective Suzuki cross-coupling, (ii) the synthesis of α-phenylalkylboronic esters by enantioselective chain extension, and (iii) the stereospecific synthesis of alkenes by eliminative cross-coupling of enantioenriched sp³-hybridized carbenoids....
Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...