Enterococci are among the leading pathogens isolated in hospital-acquired infections. Current antimicrobial options for vancomycin-
resistant enterococci (VRE) are limited. Prior data suggest that daptomycin at>6 mg/kg of body weight/day may be used
to treat enterococcal infections. We retrospectively evaluated the effectiveness and safety of high-dose daptomycin (HD-daptomycin)
therapy (>6...
Na⁺/H⁺ antiporters are ubiquitous membrane proteins that play a central role in the ion homeostasis of cells. In this study, we examined the possible role of Na⁺/H⁺ antiport in Yersinia pestis virulence and found that Y. pestis strains lacking the major Na⁺/H⁺ antiporters, NhaA and NhaB, are completely attenuated in...
We investigate a number of simple toy models to explore interesting relationships between dynamics and typicality. We start with an infinite model that has been proposed as an illustration of how nonergodic dynamics can produce interesting features that are suggestive for cosmological applications. We consider various attempts to define the...
Ion exchange resin/soil cores are a common in situ approach to estimating soil nitrogen (N) mineralization rates. However, no studies compare the two common methods of core preparation (disturbed and undisturbed). The objective of our study was to compare N mineralized and soil temperature in disturbed versus undisturbed cores of...