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Filtering by: Creator Demessie, E. Sahle Remove constraint Creator: Demessie, E. Sahle Degree Field BioResource Research Remove constraint Degree Field: BioResource Research

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  • Exploring Pactamycin Biosynthesis

    Creator:
    Roland, Jessica
    Abstract:
    Pactamycin, produced by the soil bacterium Streptomyces pactum, is a cytotoxic antibiotic that belongs to the aminocyclitol family of natural products. This antibiotic has shown various forms of biological activity, including antibacterial, antifungal, antimalarial, and antitumor activities. Despite its outstanding biological activity, the mode of formation of its pharmacophore (the...
    Resource Type:
    Honors College Thesis
    Full Text:
    into Escherichia coli BL21 pLysS. SDS-PAGE gel electrophoresis showed that the transformed E. coli

  • Biosynthetic Studies of the α-Amylase Inhibitor Trestatin in Streptomyces dimorphogenes

    Creator:
    Demessie, Ananiya A.
    Abstract:
    The prevalence of obesity and diabetes in the United States and globally has been rising in the last few decades and it continues to climb. One of the causes for this increase is the over consumption of sugars and/or carbohydrates. Among medications available to treat obesity and diabetes are the...
    Resource Type:
    Undergraduate Thesis and Presentation
    Full Text:
    +EcoRl pTMAD004 Conjugation between E. coli and Streptomyces dimorphogenes was not successful