Index Catalog // ScholarsArchive@OSU

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Creator:: Snow, Erika
Abstract:: Respiratory illnesses caused by both viral and bacterial infection are serious issues for global healthcare providers. With the emergence of new, drug-resistant forms of these diseases, innovative drugs and treatment therapies are needed. M tuberculosis is an infection that affects a large portion of the world’s population each year. Aerosol...
Resource Type:: Presentation and Undergraduate Thesis

Enzyme-Mediated Conversion of Glucolimnanthin to Bioherbicidal Breakdown Products

Creator:: Bratton, Daniel
Abstract:: The oilseed crop Limnanthes alba (white meadowfoam) is grown in Oregon. Methods were developed for the production of a liquid-based bioherbicide from meadowfoam seed meal (MSM). It was determined that glucosinolate-containing extracts of MSM can be combined with active-enzyme-containing liquid extracts of meadowfoam seed to form a fermented product rich...
Resource Type:: Undergraduate Thesis
Full Text:: Bioherbicidal Breakdown Products By Daniel Bratton An Undergraduate

Identifying microRNAs by automated phylogenetic and structural analysis

Creator:: Smith, Daniel P.
Abstract:: Motivation: It can take considerable amounts of time and effort to use existing computational tools to analyze a small RNA sequence for the purpose of determining if it is characteristic of microRNA. It is similarly tedious to search for homologs to known microRNA sequences in the rapidly growing collection of...
Resource Type:: Undergraduate Thesis
Full Text:: OF Daniel Patrick Smith for the degree of Bachelor of Science in Bioresource Research

Response of reef fish assemblages to overgrowth of the hydrocoral Millepora complanata by the crustose alga Ramicrusta sp.

Creator:: Adams, AnnaRose
Abstract:: Natural disturbances and human activities can alter the benthic composition of coral reefs and other marine ecosystems. Reef fishes that associate with particular structures on the sea floor, such as coral heads, may be vulnerable to perturbations of those habitats. The spread of a newly discovered crustose alga (Ramicrusta sp.)...
Resource Type:: Honors College Thesis

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

Creator:: Dien, Thalia
Abstract:: Background Feline injection-site sarcoma (FISS) is a rare and aggressive tumor associated with vaccines, drug injections, and skin trauma in cats. The understanding of FISS remains limited, posing challenges in its diagnosis, treatment, and prevention. In this study, we analyzed the differential expression of miRNAs and their target genes in...
Resource Type:: Undergraduate Thesis
Full Text:: practices, postvaccinal reactions, and vaccine site-associated sarcomas in cats. J Am Vet Med Assoc. 2002

Targeting Chemotherapeutic Resistance through Bcl-2

Creator:: Avery, Jonathan, Pearce, Martin, and Kolluri, Siva
Abstract:: Access restricted, at author's request, until June 20, 2021 due to proprietary information.
Resource Type:: Presentation
Full Text:: : Daniel Weber When the apoptotic pathway is impaired the cells will not die when the death signal is

Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4[Superscript R24C/R24C] or N-Ras[Superscript Q61K/Q61K] after Ultraviolet Radiation Induced Melanoma Development, Combinational Effects of Retinoid-X-Receptor α (RXRα) Ablation with Oncogenic Mutations Cdk4R24C/R24C or N-RasQ61K/Q61K after Ultraviolet Radiation Induced Melanoma Development

Creator:: Sherman, Anna
Abstract:: Summary Recent research has identified Retinoid-X-Receptorα (RXRα), a nuclear receptor involved in ligand mediated transcription, as having a protective function against the malignant transformation of melanocytes after treatment with chemical carcinogens. This study used mice selectively lacking keratinocytic RXRα in combination with an oncogenic mutation, either Cdk4[Superscript R24C/R24C] or N-Ras[Superscript...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: Sherman1,3, Daniel Coleman2,3, Stephen Hyter2,3, Gitali Indra3 and Arup Indra3,4 BioResource Research

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Creator:: Snow, Erika
Abstract:: Respiratory illnesses caused by both viral and bacterial infection are serious issues for global healthcare providers. With the emergence of new, drug-resistant forms of these diseases, innovative drugs and treatment therapies are needed. M tuberculosis is an infection that affects a large portion of the world’s population each year. Aerosol...
Resource Type:: Honors College Thesis
Full Text:: BioResource Research Daniel Arp, Dean, University Honors College I

Characterizing PM2.5 with Different Source Contributions

Creator:: Perez, Allison Mae S.
Abstract:: Ubiquitous fine particulate matter (PM2.5) exposures significantly impact global public health, yet little is known about the mechanisms causing these known adverse health effects. Oxidative stress due to PM2.5 associated chemical constituents, such as polycyclic aromatic hydrocarbons (PAHs), is a proposed possible mechanism for PM2.5 mediated health effects. Variations in...
Resource Type:: Honors College Thesis

Utilization of structure-activity-relationship for predicting chemical toxicity in primary human lung cells

Creator:: Galbreath, Amanda
Abstract:: There is a growing need to establish alternative approaches for assessing hazard from chemical exposure compared to the traditional method of animal testing. Approaches that relate chemical structure to biological activity are gaining acceptance in the field as in silico methods for characterizing and predicting chemical toxicity. In this study,...
Resource Type:: Undergraduate Thesis
Full Text:: . Krewski, Daniel, Margit Westphal, Mustafa Al-Zoughool, Maxine C. Croteau, and Melvin E. Andersen. 0

ScholarsArchive@OSU

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Enzyme-Mediated Conversion of Glucolimnanthin to Bioherbicidal Breakdown Products

Identifying microRNAs by automated phylogenetic and structural analysis

Response of reef fish assemblages to overgrowth of the hydrocoral Millepora complanata by the crustose alga Ramicrusta sp.

Gene expression analysis in feline injection-site sarcoma : differential expression of the ΔNp63 and TAp63 isoforms

Targeting Chemotherapeutic Resistance through Bcl-2

Mycobacterium tuberculosis Selective Adenosine Kinase Nucleoside Polymers for Inhalation Therapy

Characterizing PM2.5 with Different Source Contributions

Utilization of structure-activity-relationship for predicting chemical toxicity in primary human lung cells

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