Index Catalog // ScholarsArchive@OSU

Gene regulatory mechanisms of the lncRNA Fendrr

Creator:: Koehler, Monika
Abstract:: Embryonic development, where organs and major structures begin to develop, requires precise coordination of numerous gene regulatory pathways. Fendrr is an long non-coding RNA (lncRNA) that plays a role in regulating gene expression in mesodermal tissues during early embryonic development in mouse. The lateral plate mesoderm (LPM) is an earlier...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: transcript class in transcriptomes of mammals  Involved in regulating gene expression in development

Vernalization gene architecture as a predictor of growth habit in barley

Creator:: Heckart, Douglas
Abstract:: Winter hardiness in barley (Hordeum vulgare) is a trait targeted by breeding programs in order to expand the potential area of adaptation of fall-sown cereals. Vernalization requirement is an important factor in winter hardiness. A vernalization requirement is an extended period of low temperature required for transition from the vegetative...
Resource Type:: Undergraduate Thesis and Presentation

Looking for LOV : Location of LOV1 function in Nicotiana benthamiana cells

Creator:: Rutledge, Patrick
Abstract:: To initiate the defense response to an invading pathogen, plants utilize an array of immune receptors to recognize virulence effectors. Virulence effectors are released by pathogens to suppress immune responses in target hosts. These effectors are recognized by a family of resistance proteins known as nucleotide-binding leucine-rich repeat (NB-LRR) proteins....
Resource Type:: Undergraduate Thesis and Presentation

The Gut Microbiome Drives Benzo[a]pyrene's Impact on Zebrafish Behavioral Development

Creator:: Sieler, Michael J.
Abstract:: Benzo[a]pyrene (B[a]P) is a common environmental pollutant produced from the incomplete combustion of organic matter, such as fossil fuel emissions. In vertebrates, B[a]P exposure is associated with hyperactivity, though the underlying mechanisms driving this effect are undescribed. Mounting evidence indicates that the gut microbiome, which is the diverse community of...
Resource Type:: Undergraduate Thesis
Full Text:: APPROVED: _____________________________________________________ _______________ Thomas J

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks by Mudra

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks by Mudra

De novo Discovery of Novel Long Noncoding RNAs in the North American Beaver

Creator:: Kashyap, Amita
Abstract:: Long noncoding RNAs (lncRNAs) are RNA molecules that are at least 200 nucleotides long and do not encode proteins. lncRNAs have roles in gene regulation, chromatin epigenetics, and molecular scaffolding. In light of mounting evidence implicating species-specific noncoding RNAs and gene regulatory mechanisms in species adaptations, it is reasonable to...
Resource Type:: Honors College Thesis
Full Text:: nucleotides long and do not encode proteins. lncRNAs have roles in gene regulation, chromatin epigenetics

Geographic variation in the seed mycobiome of Coastal Douglas-fir (Pseudotsuga menziesii var. menziesii)

Creator:: Bergmann, Gillian E.
Abstract:: Seeds are an essential component of plant life histories, and seed endophytes have the potential to influence germination, seedling establishment and development. That said, seed endophytes are a relatively new area of study, both in the factors that influence which taxa are present and how these microbes alter plant function....
Resource Type:: Honors College Thesis
Full Text:: conditions through dormancy (Fenner and Thompson 2005). Seeds are also major agents of dispersal, which can

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Creator:: Mans, Michael-Andres D.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are a class of contaminants ubiquitous in the environment and result from the incomplete combustion of fossil fuels. Many PAHs have been identified as procarcinogenic, and are metabolized to form DNA adducts; however, other mechanisms also may contribute to toxicity and help explain differences in toxicity...
Resource Type:: Undergraduate Thesis
Full Text:: -transcriptionally regulate gene expression. Recent studies have identified dysregulation of miRNA expression in

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

Creator:: Huynh, Celine T.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are known to cause adverse health effects in the human lung. Here, we evaluated biomarkers relevant for PAH toxicity in a 3D human primary bronchial epithelial cell (HBEC) model collected from normal and asthmatic donors. We previously found that PAHs decrease cellular barrier function integrity, which...
Resource Type:: Honors College Thesis
Full Text:: –95 °C/0.5° per 5 s for validating single product amplification. Relative gene expression was

ScholarsArchive@OSU

Gene regulatory mechanisms of the lncRNA Fendrr

Vernalization gene architecture as a predictor of growth habit in barley

Looking for LOV : Location of LOV1 function in Nicotiana benthamiana cells

The Gut Microbiome Drives Benzo[a]pyrene's Impact on Zebrafish Behavioral Development

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

De novo Discovery of Novel Long Noncoding RNAs in the North American Beaver

Geographic variation in the seed mycobiome of Coastal Douglas-fir (Pseudotsuga menziesii var. menziesii)

Functional consequences of microRNA regulation by polycyclic aromatic hydrocarbons in 3D human bronchial epithelial cells

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

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