Index Catalog // ScholarsArchive@OSU

Pyruvate kinase isozymes in beef and chicken

Creator:: Strandholm, John Jeffrey, 1945-
Resource Type:: Dissertation
Full Text:: for privacyAbstract approved: Robert D. Dy on Redacted for privacy Janet M. Cardenas At least three

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Creator:: Wang, Jun-Lan
Abstract:: Low concentrations of hexachlorophene (HCP) inhibit a number of pyridine nucleotide-linked dehydrogenase enzymes. The I₅₀ HCP concentrations were 105 μM for pig heart isocitrate dehydrogenase (ICD), 65 μM for horse liver alcohol dehydrogenase, 39 μM for torula yeast glucose-6-phosphate dehydrogenase (G6PD), 6.0 μM for beef heart malate dehydrogenase, and 1.6...
Resource Type:: Dissertation
Full Text:: assistance in using the computer programs to solve the Michaelis-Menten and Hill equations; to Mrs. Dolores

Conformational transitions of nucleosome core particles monitored with time-resolved fluorescence spectroscopy

Creator:: Brown, D. W. (David W.), 1937-
Abstract:: Time-resolved fluorescence spectroscopy was used to monitor the effects of varying ionic strength on nucleosome core particle structure. Two main methods were used in these studies. First, the fluorescence anisotropy decay of bound ethidium was measured and was shown to reflect the rotational tumbling of the core particle through solution,...
Resource Type:: Dissertation
Full Text:: was raised from 10 mM to 0.35 M, with further increases being observed only above 0.65 M; we term

Characterization of neuronal nitric-oxide synthase reductase activity

Creator:: Wolthers, Kirsten R.
Abstract:: During catalysis the flavoprotein domain of neuronal nitric-oxide synthase (nNOS) shuttles NADPH-derived reducing equivalents from FAD to FMN and then to the P450-heme enabling heme-based oxygen activation and subsequent NO-synthesis. The binding of Ca²⁺-activated calmodulin (Ca²⁺-CaM) to nNOS alleviates inhibition of flavin mediated electron transfer within the diflavin domain, which...
Resource Type:: Dissertation

Model systems for structural investigations into peroxiredoxin catalysis, conformation change, and inactivation

Creator:: Perkins, Arden
Abstract:: Peroxiredoxin (Prx) enzymes catalyze the reduction of hydrogen peroxide, peroxynitrous acid, and organic peroxides, and are extremely efficient peroxidases, with k[subscript cat]/K[subscript M] on the order of 10⁷ - 10⁸ M⁻¹ s⁻¹. Besides their role in oxidative stress defense, evidence has accumulated that some eukaryotes, including humans, use Prxs as...
Resource Type:: Dissertation
Full Text:: of 10 7 – 108 M-1 s-1. Besides their role in oxidative stress defense, evidence has accumulated

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Creator:: Otto, Shauna C.
Abstract:: Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Resource Type:: Dissertation
Full Text:: how Ca2+ binding can alter the properties of the domain. 9 T ab le 1. 1: C al ci u m b in d in

Purification, characterization and comparative properties of hepatic microsomal mixed-function oxidase enzymes from rat and rainbow trout

Creator:: Williams, David Edward
Resource Type:: Dissertation
Full Text:: ( Dean of Gradu t 7 School Date thesis is presented November 11, 1982 Typed by Dolores Williams for

Ligand binding to the muscarinic receptor : equilibrium and kinetic studies

Creator:: Hirschberg, Birgit T.
Resource Type:: Dissertation
Full Text:: based on detailed kinetic studies of binding of the agonist oxotremorine M. Kinetic experiments

Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

Creator:: Guo, Chunxiao
Abstract:: Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
Resource Type:: Dissertation
Full Text:: et al., 2000). These correlations, along with the emergence of antibiotic resistant M. tuberculosis

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:: Riordan, Ruben
Abstract:: Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...
Resource Type:: Dissertation

ScholarsArchive@OSU

Pyruvate kinase isozymes in beef and chicken

The effect of hexachlorophene and related compounds on torula yeast glucose-6-phosphate dehydrogenase and some other dehydrogenase enzymes

Conformational transitions of nucleosome core particles monitored with time-resolved fluorescence spectroscopy

Characterization of neuronal nitric-oxide synthase reductase activity

Model systems for structural investigations into peroxiredoxin catalysis, conformation change, and inactivation

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Purification, characterization and comparative properties of hepatic microsomal mixed-function oxidase enzymes from rat and rainbow trout

Ligand binding to the muscarinic receptor : equilibrium and kinetic studies

Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Date

Decade

Degree Field

Degree Level

Degree Name

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search