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Filtering by: Subject Soil-structure interaction Degree Field Biochemistry and Biophysics Degree Level Doctoral

Characterization of the Structure and Dynamics of the Intrinsically Disordered Dynein Intermediate Chain and its Interactions with Regulatory Binding Partners

Creator:

Morgan, Jessica L.

Abstract:

Cells represent microcosms of spatial and temporal structural organization, with the achievement of internal spatial organization relying upon a collection of macromolecular motor complexes to transport and localize components throughout the cell. Cytoplasmic dynein is one such motor complex, and is the principal ATP-dependent motor for retrograde transport along microtubules...

Resource Type:

Dissertation

Full Text:

dynamic state into one with definite structure upon its binding interaction with a folded, structured