Index Catalog // ScholarsArchive@OSU

Dissecting DNA Damage Responses in Arabidopsis: A High-Throughput Sequencing Approach

Creator:: Brar, Anantnoor
Abstract:: A unique, permanent root-growth arrest phenotype was observed in UV-B irradiated Arabidopsis thaliana roots lacking the DNA damage response kinase ATR. Segregation analysis suggests the dependence of this phenotype on another, unidentified gene, termed ursu. High-throughput sequencing technologies were used to map and identify the causal ursu mutation. Illumina HiSeq...
Resource Type:: Honors College Thesis
Full Text:: : ____________________________________________________ John B. Hays A unique, permanent root-growth arrest phenotype was observed in UV-B

A Bayesian Treatise on the Replication Crisis in Science

Creator:: Gibson, True E.
Abstract:: Over the past decade, it has come to light that many published scientific findings cannot be reproduced. This has led to the replication crisis in science. Many researchers feel that they can no longer trust much of what they read in scientific journals, and the public is becoming ever more...
Resource Type:: Honors College Thesis
Full Text:: Inference, Bayesian Statistics Corresponding e-mail address: gibsotru@oregonstate.edu

UVB Radiation Affects the Quality of the Female Sexual Attractiveness Pheromone of the Red-Sided Garter Snake

Creator:: Vigeland, Anna E.
Abstract:: In this study, pheromone and skin lipid samples collected from red-sided garter snakes (Thamnophis sirtalis parietalis) were exposed directly to either full-spectrum light or full-spectrum plus UVB light. In addition, female and male snakes were exposed to daily doses of either full-spectrum or full-spectrum and UVB light, after which the...
Resource Type:: Honors College Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Anna E. Vigeland for

Nongenomic Actions of Steroid Hormones in the Ovine Endometrium

Creator:: Ireton, Kyle E.
Abstract:: The steroid hormone estrogen plays a crucial role in regulating certain mammalian tissues, especially female reproductive systems. Estrogen effects physiological changes in the cell by altering transcription activity for certain target genes, as a consequence of interactions between estradiol-17β (E2) and its nuclear receptor (nER). This mechanism of cellular control...
Resource Type:: Honors College Thesis
Full Text:: ABSTRACT OF THE THESIS OF Kyle E. Ireton for the degree of Honors Baccalaureate of Science in

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

Creator:: Ewton, Jessica
Abstract:: Gonadotropin-releasing hormone (GnRH) neurons are able to trigger the release of luteinizing hormone and follicle-stimulating hormone which control the maturation of oocytes and ovulation which is vital for reproduction. They are the most downstream neurons that project to the median eminence into the pituitary portal where they release GnRH. Modulation...
Resource Type:: Honors College Thesis
Full Text:: .; Herde, M. K.; Herbison, A. E.; Campbell, R. E. Dendritic Spine Plasticity in Gonadatropin-Releasing

Interaction of the human Voltage-Dependent Anion Channel 1 protein (VDAC-1) with Mycobacterium avium and its role in bacterial survival within phagocytic cells

Creator:: Pham, Tuan
Abstract:: M. avium is an opportunistic pathogen that primarily infects macrophages. In order to survive within the macrophage, M. avium secretes proteins into the host cell cytoplasm to inhibit specific functions such as phagosome acidification, altering pathways as well as initiating apoptosis. However, little is known about how those secreted proteins...
Resource Type:: Honors College Thesis
Full Text:: , siRNA Corresponding e-mail address: phamtuan@onid.oregonstated.edu

The Creation of a Bilingual Children’s Book to Promote Mental Health Services among U.S. Latin@s

Creator:: Tolmach, Oresta S.
Abstract:: Although U.S. Latin@s are more affected by major depressive disorder than non-Latin@ whites, they are less likely to utilize mental health services. The purpose of this project is to create a children’s book that promotes the utilization of mental health services among U.S. Latin@s with major depressive disorder. This book...
Resource Type:: Honors College Thesis
Full Text:: , health promotion, mental health services Corresponding e-mail address: tolmacho@onid.oregonstate.edu

Comparative analysis of genes regulating HDL function and metabolism in macaques and humans

Creator:: Clarke, Jordyn M.
Abstract:: The role of the high density lipoprotein (HDL) molecule is currently an area of great interest within the scientific community. Previously, mouse and human studies have demonstrated an inverse association between HDL cholesterol (HDL-C) levels and cardiovascular disease. Recent clinical trials, which increased HDL-C, have failed to reduce the number...
Resource Type:: Honors College Thesis
Full Text:: , cardiovascular disease, conservation Corresponding e-mail address: clarkejo@oregonstate.edu

A quantitative analysis of three-dimensional contact guidance by breast cancer cells

Creator:: Krnacik, Emma A.
Abstract:: Exploring and quantifying the parameters regarding contact guidance may provide valuable insight to the precise mechanisms controlling cell movement, especially in a three-dimensional environment. The objective of this project was to quantify the relationship between MDA-MB-231 cell morphogenesis and the geometry of the cell’s local microenvironment, which was modeled by...
Resource Type:: Honors College Thesis

Investigating the Role of the MutLα Endonuclease

Creator:: Mankaney, Gautam Naresh
Abstract:: Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Resource Type:: Honors College Thesis
Full Text:: Repair, MutL(-E705K, MutL( endonucleolytic activity Corresponding e-mail address: mankaneg@onid.orst.edu

ScholarsArchive@OSU

Dissecting DNA Damage Responses in Arabidopsis: A High-Throughput Sequencing Approach

A Bayesian Treatise on the Replication Crisis in Science

UVB Radiation Affects the Quality of the Female Sexual Attractiveness Pheromone of the Red-Sided Garter Snake

Nongenomic Actions of Steroid Hormones in the Ovine Endometrium

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

Interaction of the human Voltage-Dependent Anion Channel 1 protein (VDAC-1) with Mycobacterium avium and its role in bacterial survival within phagocytic cells

The Creation of a Bilingual Children’s Book to Promote Mental Health Services among U.S. Latin@s

Comparative analysis of genes regulating HDL function and metabolism in macaques and humans

A quantitative analysis of three-dimensional contact guidance by breast cancer cells

Investigating the Role of the MutLα Endonuclease

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