Index Catalog // Hyrax

An Evaluation of Community Attitudes Towards Gender-Based Violence in Partnership with the Community of Maunatlala, Botswana

Creatore:: Petrina, Grace E.
Abstract:: Gender-based violence (GBV) is a pervasive public health issue that continues to affect women globally. GBV is estimated to impact 37% of Botswanan women, exceeding the average global prevalence of 30%. This investigation takes place within the Botswana Global Health Initiative, a collaboration led by OSU researchers, the community of...
Resource Type:: Honors College Thesis

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

Creatore:: Ewton, Jessica
Abstract:: Gonadotropin-releasing hormone (GnRH) neurons are able to trigger the release of luteinizing hormone and follicle-stimulating hormone which control the maturation of oocytes and ovulation which is vital for reproduction. They are the most downstream neurons that project to the median eminence into the pituitary portal where they release GnRH. Modulation...
Resource Type:: Honors College Thesis

Characterization and Functionalization of Fabric for use in an Immunoassay

Creatore:: White, Natalie
Abstract:: Paper-based microfluidic assays, like the common pregnancy test, allow for rapid screening at the point- of-care at low cost and with no instrumentation. Fabric has many similar properties to paper, but is more flexible and durable, making it a promising option for use in a variety of diagnostic and screening...
Resource Type:: Honors College Thesis

Selection of an Orthogonal tRNA Synthetase for Trifluoromethyl-phenylalanine in Methanomethylophilus Alvus System

Creatore:: Eyberg, Daniel R.
Abstract:: Genetic code expansion is a technology that allows for site-specific incorporation of noncanonical amino acids into recombinant proteins at amber stop codons using engineered translational machinery. The technology allows for expanded study into proteins, derived from the integration of novel chemical functions found in noncanonical amino acids, such as fluorescence,...
Resource Type:: Honors College Thesis

A taxonomy of biomolecular features

Creatore:: North, Jacob L.
Abstract:: The scientific method applies hypothesis testing to material samples through experimentation, measurement, and data analysis, which produce representations—or features—that describe phenomena of interest. Biomolecular features come in numerous forms such as values, matrices, graphs, three-dimensional structures, trajectories, and molecular surfaces. Researchers have tested thousands of features related to protein molecules...
Resource Type:: Honors College Thesis

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Creatore:: Pinckney, Seth H.
Abstract:: The nucleocapsid protein (N protein) of the severe acute respiratory syndrome coronavirus 2 is known to play an essential part of the virus’ functions. The N protein can protect and package the large 29,903 nucleotide genomic RNA whilst also interacting with structural membrane protein M and the spike protein S....
Resource Type:: Honors College Thesis

Impaired epidermal homeostasis in Bcl11bR3S/R3S homozygous mutant mice

Creatore:: Kelly, Avalon G.
Abstract:: BCL11B, also known as CTIP2, is a transcription factor which plays a critical role in the regulation and development of many tissues and organ systems, including the skin. A 2019 study by Goos et. al. uncovered a novel point mutation in BCL11B gene that converted the Arginine(R)-3 residue to a...
Resource Type:: Honors College Thesis

A Panel of Histone H3 Mutations to Investigate Centromere Maintenance and Gene Silencing

Creatore:: Geisler, Mark S.
Abstract:: Histones, as part of nucleosomes, are responsible for DNA packaging in chromosomes. They also affect DNA expression by a multitude of post-translational modifications, especially prevalent on the amino terminus of histones. Co-activator protein complexes “write”, “read”, or “erase” histone modifications, and in balance determine which sections of DNA are free...
Resource Type:: Honors College Thesis

A Bayesian Treatise on the Replication Crisis in Science

Creatore:: Gibson, True E.
Abstract:: Over the past decade, it has come to light that many published scientific findings cannot be reproduced. This has led to the replication crisis in science. Many researchers feel that they can no longer trust much of what they read in scientific journals, and the public is becoming ever more...
Resource Type:: Honors College Thesis

The Cathelicidin Anti-microbial peptide gene alters the mouse gut microbiome

Creatore:: Rouches, Miles V.
Abstract:: The gut microbiome influences human disease including Type 2 diabetes, obesity and metabolic syndrome and interacts with the innate immune system. The human cathelicidin antimicrobial peptide (hCAMP), an important component of the innate immune system, and vitamin D and xanthohumol, a natural compound found in beer hops, regulate its expression....
Resource Type:: Honors College Thesis

Hyrax

An Evaluation of Community Attitudes Towards Gender-Based Violence in Partnership with the Community of Maunatlala, Botswana

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

Characterization and Functionalization of Fabric for use in an Immunoassay

Selection of an Orthogonal tRNA Synthetase for Trifluoromethyl-phenylalanine in Methanomethylophilus Alvus System

A taxonomy of biomolecular features

Characterization of the SARS-CoV-2 Nucleocapsid Protein and the Binding to Different Sections of the SARS-CoV-2 Genome

Impaired epidermal homeostasis in Bcl11bR3S/R3S homozygous mutant mice

A Panel of Histone H3 Mutations to Investigate Centromere Maintenance and Gene Silencing

A Bayesian Treatise on the Replication Crisis in Science

The Cathelicidin Anti-microbial peptide gene alters the mouse gut microbiome

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