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Filtering by: Creator Bloomquist, Gilbert Ruben Remove constraint Creator: Bloomquist, Gilbert Ruben Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics Non-Academic Affiliation Oregon State University. Graduate School Remove constraint Non-Academic Affiliation: Oregon State University. Graduate School

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  • Structural requirements for adenovirus DNA replication

    Creator:
    Hu, Chin-Hwa
    Abstract:
    The adenovirus replication origins reside in the inverted terminal repetition (ITR) sequences. Replication proceeds unidirectionally by a strand-displacement mechanism from either or both origins to produce duplex daughter DNA plus a displaced parental strand. The displaced strand can be duplicated by two different routes. The cis pathway involves intramolecular hybridization...
    Resource Type:
    Dissertation
    Full Text:
    been found in infected cells (Ruben et al., 1983; Graham, 1984). The circular forms of the viral DNA

  • Functional analysis of novel β-catenin mutants

    Creator:
    Al-Fageeh, Mohamed B.
    Abstract:
    β-catenin is a multi functional protein that is involved in cell-cell adhesion and cell signaling. In non-stimulated cells, β-catenin is tightly down-regulated by GSK-3β-dependent phosphorylation at Ser and Thr residues, followed by rapid ubiquitination and proteasomal degradation. It is well established that mutations within the regulatory GSK-3β region lead to...
    Resource Type:
    Masters Thesis