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Filtering by: Creator Fujita, Rod Remove constraint Creator: Fujita, Rod Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics Rights Statement In Copyright Remove constraint Rights Statement: In Copyright

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Cytoskeletal regulation in cell motility and invasion

Creator:

Jang, Hyo Sang

Abstract:

Cell motility and invasion are important for development, immunity, wound healing, and tumor cell metastasis. Cells on two dimensional substrates migrate in three steps: protrusion of the front end, translocation of the cell body, and retraction of the rear end. For cells to migrate efficiently, these steps need to be...

Resource Type:

Dissertation

Full Text:

-terminal rod domain (Rod). Vinculin binds to the SLR of α-actinin or the talin Rod domain via the N
Building a bridge from chromosomes to microtubules in Neurospora crassa

Creator:

Friedman, Steven

Abstract:

DNA is often described as the “blueprint for life”. In eukaryotes this information is contained within linear chromosomes of varying size and number. During cell division, the chromosomes must be faithfully segregated into each daughter cell to avoid disease and sustain life. This process is carried out by the kinetochore...

Resource Type:

Dissertation
Antioxidant mechanisms of ascorbate and (R)-α-lipoic acid in aging and transition metal ion-mediated oxidative stress

Creator:

Shu, Jung Hyuk

Abstract:

Oxidative stress is the major driving force behind the aging process and many age-related diseases. However, direct experimental evidence of whether antioxidants, such as ascorbate (AA) and lipoic acid (LA) can slow the progression of aging process and/or reduce risks of developing degenerative disease is largely absent. This suggests a...

Resource Type:

Dissertation
Transcriptional regulation of the human cathelicidin antimicrobial peptide gene

Creator:

Guo, Chunxiao

Abstract:

Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...

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Dissertation

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Academic Affiliation

Biochemistry and Biophysics4

Advisor

Frei, Balz B.1
Freitag, Michael1
Gombart, Adrian F.1
Greenwood, Jeffrey1
Hagen, Tory M.1

Commencement Year

Commencement Year range begin – Commencement Year range end

Current results range from 2004 to 2018

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Committee Member

Barbar, Elisar1
Buermeyer, Andrew1
Dashwood, Roderick1
Dolan, Brian1
Freitag, Michael1
more Committee Members »

Creator

Friedman, Steven1
Guo, Chunxiao1
Jang, Hyo Sang1
Shu, Jung Hyuk1

Date

Date range begin – Date range end

Current results range from 2003 to 2017

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Decade

2010-20192
2000-20092

Degree Field

Biochemistry and Biophysics[remove]4

Degree Level

Doctoral4

Degree Name

Doctor of Philosophy (Ph.D.)4

Language

English [eng]4

License

All rights reserved4

Non-Academic Affiliation

Oregon State University. Graduate School4

Peer Reviewed

No4

Resource Type

Dissertation4

Rights Statement

In Copyright[remove]4

Subject

Actin1
Aging -- Prevention1
Calpain1
Cell migration1
Cells -- Motility1
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