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Filtering by: Creator Mills, Dallice Remove constraint Creator: Mills, Dallice Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics Subject Adenoviruses Remove constraint Subject: Adenoviruses

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  • Adenovirus replication in trans : a new replication pathway

    Creator:
    Ahern, Kevin
    Abstract:
    Replication of plasmid molecules containing either a left-end or a right-end adenovirus origin was investigated. When the plasmids were linearized to expose their respective adenovirus termini, mixed, and transfected with helper adenovirus DNA into the human 293 cell line, a new molecule was detected. The new molecule was the size...
    Resource Type:
    Dissertation
    Full Text:
    my other committee members, Dr. Ken van Holde, Dr. Chris Mathews, Dr. Dallice Mills, and Dr. Gene

  • Sequence conversion during adenovirus DNA replication

    Creator:
    Bennett, Kelly L.
    Abstract:
    The work in this thesis has provided conclusive genetic evidence that "panhandle" intermediates form during adenovirus replication. Adenovirus chromosomes lacking 51 by from their left -hand termini are infectious and capable of regenerating the missing origin sequence. Yet if an entire inverted terminal repeat is removed, the adenovirus chromosome is...
    Resource Type:
    Dissertation
    Full Text:
    Mills, and Dr. Jane Aldrich, for their efforts. A special thanks is in order for Dr. Christopher