Index Catalog // ScholarsArchive@OSU

Studies of genes expressed in the brain and regulated by transforming growth factor β

Creator:: Solem, Michele Lee
Resource Type:: Dissertation
Full Text:: the Brain and Regulated by Transforming Growth Factor 5. Abstract approved: David W. Barnes Human

Nonsenecent serum-free mouse proastroblasts : extended culture, growth responses in vitro, and application to the culture of human embryonic astrocytes

Creator:: Loo, Deryk Thomas
Abstract:: Mouse embryo cells cultured in vitro in serum-supplemented media undergo growth crisis, resulting in the loss of genomically normal cells prior to the appearance of established, aneuploid cell lines. I used the technique of serum-free cell culture to develop a serum-free mouse embryo (SFME) cell line in which serum was...
Resource Type:: Dissertation
Full Text:: . Abstract approved:4Redacted for Privacy David W. Barnes Mouse embryo cells cultured in vitro in serum

Purification and identification of a 100 kDa protein, which is tyrosine-phosphorylated by EGF stimulation in SFME cell

Creator:: Murayama, Kaoru
Abstract:: Serum-free mouse embryo (SFME) cells, which were derived from 16-day-old Balb/c mouse embryo brain, grow in absence of serum without losing genomic normality or proliferative potential, and require epidermal growth factor (EGF) for normal growth. EGF is a well studied mitogen that binds to a specific receptor on the cell...
Resource Type:: Masters Thesis
Full Text:: Stimulation in SFME Cells. Abstract approved: David W. Barnes Serum-free mouse embryo (SFME) cells

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Creator:: Wise, Mitchell L.
Resource Type:: Dissertation
Full Text:: concerning enzyme kinetics and Dr. David Williams for pointing out the flavin binding motif in the N

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

Creator:: Wolk, Chelsea
Abstract:: A fundamental difference between prokaryotic and eukaryotic cells is the presence of membrane bound organelles in eukaryotes. The dynamics of membrane trafficking within the cell are responsible for everything from intercellular communication and cell homeostasis, to mitosis, cell migration, and differentiation. These processes require exocytosis and compensatory endocytosis, often working...
Resource Type:: Dissertation
Full Text:: . Weihong Qiu, and Dr. David Hendrix. Also, this type of graduate work would not be possible without

UVB Radiation Affects the Quality of the Female Sexual Attractiveness Pheromone of the Red-Sided Garter Snake

Creator:: Vigeland, Anna E.
Abstract:: In this study, pheromone and skin lipid samples collected from red-sided garter snakes (Thamnophis sirtalis parietalis) were exposed directly to either full-spectrum light or full-spectrum plus UVB light. In addition, female and male snakes were exposed to daily doses of either full-spectrum or full-spectrum and UVB light, after which the...
Resource Type:: Honors College Thesis
Full Text:: (Kerr and McElroy, 1993). This rise in UVB levels has been linked to physiological stress in aquatic

Ti plasmid coded protein in Agrobacterium tumefaciens

Creator:: Engelgau, Michael Maurice
Abstract:: Agrobacterium tumefaciens is a plant pathogenic bacteria which incites crown gall tumors. Although virulence has been associated with a 97-156 Mdalton "tumor-inducing" (Ti) plasmid, few potential plasmid gene products have been identified. The objective of this study was to identify plasmid-coded gene products through a comparison of protein fingerprints of...
Resource Type:: Masters Thesis
Full Text:: mediated event stimulated in the tumor tissue environment. In view of this, the in planta "Kerr Cross

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Creator:: Otto, Shauna C.
Abstract:: Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Resource Type:: Dissertation

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Creator:: Vulpanovici, Florina Alexandra
Abstract:: This thesis details investigations of marine cyanobacterial secondary metabolism, with emphasis on a strain of Phormidium sp. collected in Indonesia. These studies assessed the effects of nineteen putative elicitor compounds on the growth and metabolite production of five species of marine cyanobacteria, biosynthetic investigation of an intriguing secondary metabolite, phormidolide,...
Resource Type:: Dissertation
Full Text:: their friendship, and Lisa Nogle, Rebecca Medina, David Blanchard, Jennifer Turcot, Mitam Musafija

Biological activity of avian myeloblastosis virus RNA in cell-free systems for protein synthesis

Creator:: Olson, Kenneth Charles
Abstract:: Avian myeloblastosis virus RNA was fractionated into a high molecular weight RNA and a low molecular weight RNA fraction by sucrose density centrifugation. The larger RNA component had a sedimentation constant of 65S and the low molecular weight RNA about 4S. The low molecular RNA has two biological properties of...
Resource Type:: Masters Thesis

DNA precu[r]sor compartmentation in mammalian cells : metabolic and anti-metabolic studies of nuclear and mitochondrial DNA synthesis

Creator:: Bestwick, Richard Keith
Abstract:: This dissertation describes an investigation of DNA precursor supply for mitochondrial and nuclear DNA synthesis in HeLa cells and Mouse L-cells. HeLa cells were used for the quantitation of cellular and mitochondrial deoxyribonucleoside triphosphate (dNTP) and ribonucleoside triphosphate (rNTP) pools and of changes in pools in response to treatment with...
Resource Type:: Dissertation

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:: Riordan, Ruben
Abstract:: Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...
Resource Type:: Dissertation

Building a bridge from chromosomes to microtubules in Neurospora crassa

Creator:: Friedman, Steven
Abstract:: DNA is often described as the “blueprint for life”. In eukaryotes this information is contained within linear chromosomes of varying size and number. During cell division, the chromosomes must be faithfully segregated into each daughter cell to avoid disease and sustain life. This process is carried out by the kinetochore...
Resource Type:: Dissertation
Full Text:: sequencing data obtained by David Catcheside (Flinders University, South Australia) and Jane Landolin

ScholarsArchive@OSU

Studies of genes expressed in the brain and regulated by transforming growth factor β

Nonsenecent serum-free mouse proastroblasts : extended culture, growth responses in vitro, and application to the culture of human embryonic astrocytes

Purification and identification of a 100 kDa protein, which is tyrosine-phosphorylated by EGF stimulation in SFME cell

Biosynthesis and enzymology of conjugated polyenoic fatty acid production in macrophytic marine algae

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

UVB Radiation Affects the Quality of the Female Sexual Attractiveness Pheromone of the Red-Sided Garter Snake

Ti plasmid coded protein in Agrobacterium tumefaciens

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Biosynthesis, production and structural studies of secondary metabolites in cultured marine cyanobacteria

Biological activity of avian myeloblastosis virus RNA in cell-free systems for protein synthesis

DNA precu[r]sor compartmentation in mammalian cells : metabolic and anti-metabolic studies of nuclear and mitochondrial DNA synthesis

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Building a bridge from chromosomes to microtubules in Neurospora crassa

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