Index Catalog // ScholarsArchive@OSU

Prostaglandin F α-induced signal transduction mechanism regulating the secretion of oxytocin from the bovine corpus lutem

Creator:: Orwig, Kyle Edwin
Resource Type:: Dissertation
Full Text:: C (PKC) present in the bovine corpus luteum (CL) and their subcellular distribution. In addition

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

Creator:: Baker, Kasie J.
Abstract:: The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
Resource Type:: Dissertation
Full Text:: THE DISSERTATION OF Kasie J. Baker for the degree of Doctor of Philosophy in Biochemistry and

Partial purification and characterization of the atrial muscarinic acetylcholine receptor

Creator:: Herron, G. Scott
Resource Type:: Dissertation
Full Text:: Muscarinic Acetylcholine Receptor AN ABSTRACT OF THE THESIS OF G. Scott Herron for the degree of Doctor of

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Creator:: Ramsdell, Howard Scott
Abstract:: Senecio jacobaea (tansy ragwort) is a common weed in the Pacific Northwest that contains toxic pyrrolizidine alkaloids (PAs). Jacobine, the major PA in Senecio jacobaea, was incubated with rat liver microsomes and metabolites were isolated by high performance liquid chromatography (HPLC) and identified by mass spectrometric analysis. Metabolites included a...
Resource Type:: Dissertation
Full Text:: by Howard Scott Ramsdell A THESIS submitted to Oregon State University in partial

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Creator:: Hanson, Eric Scott
Resource Type:: Dissertation
Full Text:: 1.7. Allosteric regulation of the T4 RNR 26 2.1. Region alignment of T4 and C. moewussi sequences that

Antioxidant mechanisms of ascorbate and (R)-α-lipoic acid in aging and transition metal ion-mediated oxidative stress

Creator:: Shu, Jung Hyuk
Abstract:: Oxidative stress is the major driving force behind the aging process and many age-related diseases. However, direct experimental evidence of whether antioxidants, such as ascorbate (AA) and lipoic acid (LA) can slow the progression of aging process and/or reduce risks of developing degenerative disease is largely absent. This suggests a...
Resource Type:: Dissertation
Full Text:: Abstract approved: Balz B. Frei c/Tory M.'Hagen Oxidative stress is the major driving force behind the

Vaccinia virus ribonucleotide reductase : regulation of the gene products and characterization of the recombinant small subunit protein

Creator:: Howell, Meredith L.
Abstract:: Ribonucleotide reductase is a remarkable enzyme that catalyzes the rate-limiting step in the synthesis of the 2'-deoxynucleoside triphosphates. The intent of this project was to characterize the ribonucleotide reductase encoded by the orthopoxvirus, vaccinia. The first objective was to study the structural and functional features of the viral small subunit...
Resource Type:: Dissertation
Full Text:: and Characterization of the Recombinant Small Subunit Protein Abstract approved: C. K. Mathews

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Creator:: Riordan, Ruben
Abstract:: Alzheimer’s Disease (AD) is a neurodegenerative pathology currently affecting nearly 44 million individuals worldwide, yet there are not currently any effective treatments or preventions for AD despite the rapid development in our understanding of the disease over the last four decades. The medical and sanitary innovations of the last century...
Resource Type:: Dissertation
Full Text:: grateful to my many colleagues and friends, Dr. Kate Shay, Dr. Malcolm Lowry, Carmen Wong, and Scott

Environmental influences on monoterpenes and phenolics of Mentha piperita

Creator:: Yao, Cheng C.
Abstract:: Vegetatively propagated peppermint (Mentha piperita L., cv. Black Mitcham) was used to determine the effects of night temperatures (8°C vs 25°C) on the plant growth in terms of fresh weight and leaf area, and on metabolite contents. The plants were sampled after 14 days, 21 days and 28 days in...
Resource Type:: Masters Thesis
Full Text:: Mentha piperita AN ABSTRACT OF THE THESIS OF Cheng C. Yao for the degree of Master of Science in

Identifying the Enzymes Responsible for Reduction of Doxorubicin to its Cardiotoxic Metabolite Doxorubicinol using a Novel Immunoclearing Approach

Creator:: Breysse, Daniel H.
Abstract:: Doxorubicin is a widely used cancer therapeutic, but its effectiveness is limited by cardiotoxic side effects. Evidence suggests cardiotoxicity is due not to doxorubicin, but rather its metabolite, doxorubicinol. Identification of the enzymes responsible for doxorubicinol formation is important in developing strategies to prevent cardiotoxicity. In this study, the contributions...
Resource Type:: Masters Thesis
Full Text:: ……………………...61 C. Abbreviations…………………………………………………………….64 ix LIST OF FIGURES

ScholarsArchive@OSU

Prostaglandin F α-induced signal transduction mechanism regulating the secretion of oxytocin from the bovine corpus lutem

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

Partial purification and characterization of the atrial muscarinic acetylcholine receptor

Toxicity and in vitro metabolism of Senecio jacobaea pyrrolizidine alkaloids in the rat and mouse

Bacteriophage T4 ribonucleotide reductase : genes and proteins

Antioxidant mechanisms of ascorbate and (R)-α-lipoic acid in aging and transition metal ion-mediated oxidative stress

Vaccinia virus ribonucleotide reductase : regulation of the gene products and characterization of the recombinant small subunit protein

The Role of Cellular Senescence in the Development of Alzheimer's Disease

Environmental influences on monoterpenes and phenolics of Mentha piperita

Identifying the Enzymes Responsible for Reduction of Doxorubicin to its Cardiotoxic Metabolite Doxorubicinol using a Novel Immunoclearing Approach

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