Index Catalog // ScholarsArchive@OSU

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

Creator:: Ewton, Jessica
Abstract:: Gonadotropin-releasing hormone (GnRH) neurons are able to trigger the release of luteinizing hormone and follicle-stimulating hormone which control the maturation of oocytes and ovulation which is vital for reproduction. They are the most downstream neurons that project to the median eminence into the pituitary portal where they release GnRH. Modulation...
Resource Type:: Honors College Thesis
Full Text:: Hormone Expressing Neurons. Abstract approved: a Patrick Chappell Gonadotropin-releasing hormone (GnRH

The mechanism of interaction of the linker histone with DNA and nucleosomes

Creator:: Ellen, Thomas Patrick
Abstract:: This dissertation examines the interaction of the linker histone with DNA and with nucleosomes. The first goal of the project was to characterize the interaction of the linker histone with DNA. Three factors previously reported to influence the linker histone's interaction with DNA were examined: ratio of linker histone to...
Resource Type:: Dissertation
Full Text:: with DNA and Nucleosomes by Thomas Patrick Ellen A DISSERTATION submitted to Oregon State

Enzyme associations in deoxyribonucleotide biosynthesis : anti-idiotypic antibodies as probes for direct protein-protein interactions

Creator:: Young, James Patrick
Abstract:: The ability to faithfully replicate DNA is dependent upon the maintenance and regulation of its precursors, the deoxyribonucleoside triphosphates. Enzymes encoded by the bacteriophage T4 have been widely used as models of biochemical processes. A body of evidence supports the concept that the bacteriophage T4 enzymes involved in deoxyribonucleotide biosynthesis...
Resource Type:: Dissertation
Full Text:: James Patrick Young A THESIS submitted to Oregon State University in partial fulfillment of the

Studies on the growth inhibition and differentiation of serum-free mouse embryo (SFME) cells

Creator:: Varga Weisz, Patrick D.
Abstract:: Serum-free mouse embryo (SFME) cells are derived in medium in which serum is replaced with growth factors and other supplements. They display unusual properties. They do not lose proliferative potential or show gross chromosomal aberration upon extended culture, they depend on epidermal growth factor (EGF) for survival, and are reversibly...
Resource Type:: Dissertation
Full Text:: Serum-free Mouse Embryo (SFME) Cells by Patrick D. Varga Weisz A THESIS submitted to Oregon State

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Creator:: Padgitt-Cobb, Lillian K.
Abstract:: Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an extensive history of cultivation and use in brewing, as a textile, and for its therapeutic properties. Hop is prized for its ability to produce a variety of aromatic and flavor compounds, as well as compounds with anti-microbial...
Resource Type:: Dissertation
Full Text:: : David A. Hendrix Hop (Humulus lupulus L. var. lupulus) is a diploid, dioecious plant with an exten

Understanding Circadian and Light-activated Transcriptional Regulatory Changes During Aging in Drosophila melanogaster

Creator:: Fey, Rosalyn M.
Abstract:: Systems biology is a powerful approach which considers and sheds light on all of the puzzle pieces which make up complex biological processes, and is an effective alternative to unraveling these processes using traditional molecular approaches alone. It is a natural companion approach for computational biology, which leverages the power...
Resource Type:: Dissertation
Full Text:: Drosophila melanogaster Abstract approved: David A. Hendrix Systems biology is a powerful approach which

Specificity, Allostery, and Multivalency in Binding to the Hub Protein LC8

Creator:: Estelle, Aidan B.
Abstract:: Interactions between proteins are essential to life, driving and regulating a majority of processes within all living cells. Study of protein-protein interactions reveals that some proteins act as hubs within networks of interactions, binding to many partner proteins. These hubs therefore are of particular importance to understanding protein function, interwoven...
Resource Type:: Dissertation
Full Text:: time when I was a slow learner. Patrick, thank you for teaching me so much about NMR, and also for

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Creator:: Otto, Shauna C.
Abstract:: Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Resource Type:: Dissertation
Full Text:: approved: Colin P. Johnson Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiqui

Exposure to the Mycotoxin Zearalenone Impairs Embryonic Development in Zebrafish

Creator:: Sidebotham, Nicole A.
Abstract:: A study was conducted to evaluate the developmental toxicity of three commonly detected mycotoxins in food (deoxynivalenol, patulin, and zearalenone) using the zebrafish (Danio rerio) model. Mycotoxin exposures were carried out at five concentrations (0.0064, 0.064, 0.64, 6.4, and 64 μM). Morphological and photomotor screenings were conducted at 24 hours...
Resource Type:: Honors College Thesis
Full Text:: Zebrafish by Nicole Sidebotham A PROJECT submitted to

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

Creator:: Baker, Kasie J.
Abstract:: The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
Resource Type:: Dissertation
Full Text:: Signaling Abstract approved: ______________________________________________________ Afua A

ScholarsArchive@OSU

The analysis of kisspeptin neuronal exosomes and their effects on neuronal plasticity of downstream gonadotropin-releasing hormone expressing neurons

The mechanism of interaction of the linker histone with DNA and nucleosomes

Enzyme associations in deoxyribonucleotide biosynthesis : anti-idiotypic antibodies as probes for direct protein-protein interactions

Studies on the growth inhibition and differentiation of serum-free mouse embryo (SFME) cells

Towards Resolving Functional and Evolutionary Mysteries of the Large and Heterozygous Genome of Hop (Humulus lupulus) and the Cannabaceae Family Using Genomic Data Science

Understanding Circadian and Light-activated Transcriptional Regulatory Changes During Aging in Drosophila melanogaster

Specificity, Allostery, and Multivalency in Binding to the Hub Protein LC8

Conformational Consequences: Calcium Regulates the Association Between Dysferlin C2A & PI(4,5)P2

Exposure to the Mycotoxin Zearalenone Impairs Embryonic Development in Zebrafish

Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

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